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TNF receptor-associated factor 2 is a protein that in humans is encoded by the TRAF2 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around TRAF2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TRAF2 shows recurring relationship patterns in the source. For example, TRAF2 → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of NF-kappaB-inducing kinase activity, AIP1-IRE1 complex, apoptotic process, CD40 receptor binding, CD40 receptor complex, cell cortex, cellular response to nitric oxide, cytoplasm, cytoplasmic side of plasma membrane, cytosol, death-inducing signaling complex assembly, enzyme binding, I-kappaB kinase/NF-kappaB signaling, identical protein binding, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, IRE1-TRAF2-ASK1 complex, lipid binding, membrane raft, metal ion binding Another extracted example is TRAF2 → ASK1, Baculoviral IAP, BCL10, BIRC2, CASP8AP2, Caveolin, CD134, CD137, CD27, CD40, CFLAR, CHUK, EDARADD, HIVEP3, IKK2, Low, MAP3K1, MAP3K14, MAP3K7IP2, MAP4K2. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
protein bp gene tnf chr human band receptor factor chromosome location traf mouse associated signal activation receptors function encoded search
TTTA extracted 176 structured relationships around TRAF2. Examples in this analysis include TRAF2 → 2.3.2.27 → ↗ and TRAF2 → Aliases → TRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF117. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TRAF2 | 2.3.2.27 | ↗ | 1.00 | infobox |
| TRAF2 | Aliases | TRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF117 | 1.00 | infobox |
| TRAF2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D, 1CA4, 1CA9, 1CZY, 1CZZ, 1D00, 1D01, 1D0A, 1D0J, 1F3V, 1QSC, 3KNV, 3M06, 3M0A | 1.00 | infobox |
| TRAF2 | Band | 9q34.3 | 1.00 | infobox |
| TRAF2 | Band | 2|2 A3 | 1.00 | infobox |
| TRAF2 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| TRAF2 | Bgee | lymph node | 1.00 | infobox |
| TRAF2 | Bgee | right testis | 1.00 | infobox |
| TRAF2 | Bgee | cerebellar hemisphere | 1.00 | infobox |
| TRAF2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| TRAF2 | Bgee | granulocyte | 1.00 | infobox |
| TRAF2 | Bgee | left testis | 1.00 | infobox |
| TRAF2 | Bgee | ganglionic eminence | 1.00 | infobox |
| TRAF2 | Bgee | gonad | 1.00 | infobox |
| TRAF2 | Bgee | spleen | 1.00 | infobox |
| TRAF2 | Bgee | thymus | 1.00 | infobox |
| TRAF2 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| TRAF2 | Bgee | lactiferous gland | 1.00 | infobox |
| TRAF2 | Bgee | spermatocyte | 1.00 | infobox |
| TRAF2 | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| TRAF2 | Bgee | intestinal villus | 1.00 | infobox |
| TRAF2 | Bgee | right kidney | 1.00 | infobox |
| TRAF2 | Bgee | ventricular zone | 1.00 | infobox |
| TRAF2 | BioGPS | More reference expression data | 1.00 | infobox |
| TRAF2 | Chr. | Chromosome 9 (human) | 1.00 | infobox |
| TRAF2 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| TRAF2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TRAF2 | End | 136,926,607 bp | 1.00 | infobox |
| TRAF2 | End | 25,436,952 bp | 1.00 | infobox |
| TRAF2 | Ensembl | ENSG00000127191 | 1.00 | infobox |
The concept neighborhoods around TRAF2 bring nearby vocabulary together. In this analysis, examples include Iap, Traf1 and Traf. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TRAF2, one of the stronger structural bridges in this analysis connects TRAF2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TRAF2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TRAF2 · EN edition · Analysis: TopicsToTalkAbout