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TRAF2

TNF receptor-associated factor 2 is a protein that in humans is encoded by the TRAF2 gene.

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Interactions

35 related topics

Function

5 related topics

Overview

2 related topics

Key facts & relationships

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2.3.2.27
Aliases
TRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF117
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D, 1CA4, 1CA9, 1CZY, 1CZZ, 1D00, 1D01, 1D0A, 1D0J, 1F3V, 1QSC, 3KNV, 3M06, 3M0A
Band
9q34.3 · 2|2 A3
Bgee
mucosa of transverse colon · lymph node · right testis · cerebellar hemisphere · right hemisphere of cerebellum
BioGPS
More reference expression data

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Overview

Function

Interactions

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Map overview Semantic statistics

TRAF2

Nodes46
Edges45
Triples176
Avg. degree1.96
Density0.043478
Components1

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TRAF2

Top relations

Gene ontology · 67
TRAF2 → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of NF-kappaB-inducing kinase activity, AIP1-IRE1 complex, apoptotic process, CD40 receptor binding, CD40 receptor complex, cell cortex, cellular response to nitric oxide, cytoplasm, cytoplasmic side of plasma membrane, cytosol, death-inducing signaling complex assembly, enzyme binding, I-kappaB kinase/NF-kappaB signaling, identical protein binding, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, IRE1-TRAF2-ASK1 complex, lipid binding, membrane raft, metal ion binding
related to Interactions · 35
TRAF2 → ASK1, Baculoviral IAP, BCL10, BIRC2, CASP8AP2, Caveolin, CD134, CD137, CD27, CD40, CFLAR, CHUK, EDARADD, HIVEP3, IKK2, Low, MAP3K1, MAP3K14, MAP3K7IP2, MAP4K2
Bgee · 18
TRAF2 → cerebellar hemisphere, crypt of lieberkuhn of small intestine, ganglionic eminence, gonad, granulocyte, intestinal villus, lactiferous gland, left testis, lymph node, mesenteric lymph nodes, mucosa of transverse colon, right hemisphere of cerebellum, right kidney, right testis, spermatocyte, spleen, thymus, ventricular zone
RNA expression pattern · 18
TRAF2 → cerebellar hemisphere, crypt of lieberkuhn of small intestine, ganglionic eminence, gonad, granulocyte, intestinal villus, lactiferous gland, left testis, lymph node, mesenteric lymph nodes, mucosa of transverse colon, right hemisphere of cerebellum, right kidney, right testis, spermatocyte, spleen, thymus, ventricular zone
related to Function · 13
TRAF2 → IAP, IAPs, MAPK8/JNK, Multiple, NF-κB, The, This, TNF, TNF-alpha-mediated, TNF-induced, TRADD, TRAF, TRAF1
Band · 2
TRAF2 → 2|2 A3, 9q34.3
Chr. · 2
TRAF2 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
TRAF2 → 136,926,607 bp, 25,436,952 bp
2.3.2.27 · 1
TRAF2 → ↗
Aliases · 1
TRAF2 → TRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF117

Important terminology Word statistics

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Important terminology

protein bp gene tnf chr human band receptor factor chromosome location traf mouse associated signal activation receptors function encoded search

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TRAF22.3.2.271.00infobox
TRAF2AliasesTRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF1171.00infobox
TRAF2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D, 1CA4, 1CA9, 1CZY, 1CZZ, 1D00, 1D01, 1D0A, 1D0J, 1F3V, 1QSC, 3KNV, 3M06, 3M0A1.00infobox
TRAF2Band9q34.31.00infobox
TRAF2Band2|2 A31.00infobox
TRAF2Bgeemucosa of transverse colon1.00infobox
TRAF2Bgeelymph node1.00infobox
TRAF2Bgeeright testis1.00infobox
TRAF2Bgeecerebellar hemisphere1.00infobox
TRAF2Bgeeright hemisphere of cerebellum1.00infobox
TRAF2Bgeegranulocyte1.00infobox
TRAF2Bgeeleft testis1.00infobox
TRAF2Bgeeganglionic eminence1.00infobox
TRAF2Bgeegonad1.00infobox
TRAF2Bgeespleen1.00infobox
TRAF2Bgeethymus1.00infobox
TRAF2Bgeemesenteric lymph nodes1.00infobox
TRAF2Bgeelactiferous gland1.00infobox
TRAF2Bgeespermatocyte1.00infobox
TRAF2Bgeecrypt of lieberkuhn of small intestine1.00infobox
TRAF2Bgeeintestinal villus1.00infobox
TRAF2Bgeeright kidney1.00infobox
TRAF2Bgeeventricular zone1.00infobox
TRAF2BioGPSMore reference expression data1.00infobox
TRAF2Chr.Chromosome 9 (human)1.00infobox
TRAF2Chr.Chromosome 2 (mouse)1.00infobox
TRAF2DatabasesNCBI: entry; OMA: entry1.00infobox
TRAF2End136,926,607 bp1.00infobox
TRAF2End25,436,952 bp1.00infobox
TRAF2EnsemblENSG000001271911.00infobox

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