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TRAF1: Interactions, Function & Overview

TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.

Language: English [EN]
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TRAF1 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around TRAF1.

Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
105
Concept neighborhoods
10
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 13 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TRAF1, EBI6, MGC:10353, TNF receptor associated factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D
Band
9q33.2 · 2|2 B
Bgee
granulocyte · right coronary artery · Descending thoracic aorta · ascending aorta · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

  • IAP Inhibitor of apoptosis protein

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TRAF1 connects Entity context

The extracted context around TRAF1 shows recurring relationship patterns in the source. For example, TRAF1 → appendix, ascending aorta, blood, Dermatocranium, Descending thoracic aorta, granulocyte, left coronary artery, lumbar subsegment of spinal cord, lymph node, mandible, maxilla, membranous bone, mesenteric lymph nodes, popliteal artery, right coronary artery, right lung lobe, spleen, thymus, tibial arteries, tibial nerve Another extracted example is TRAF1 → apoptotic process, cytoplasm, cytosol, identical protein binding, positive regulation of NF-kappaB transcription factor activity, protein binding, protein-containing complex, protein-containing complex assembly, regulation of apoptotic process, regulation of extrinsic apoptotic signaling pathway, regulation of tumor necrosis factor-mediated signaling pathway, signal transduction, thioesterase binding, tumor necrosis factor receptor binding, ubiquitin protein ligase binding, zinc ion binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

TRAF1

Top relations

Bgee · 20
TRAF1 → appendix, ascending aorta, blood, Dermatocranium, Descending thoracic aorta, granulocyte, left coronary artery, lumbar subsegment of spinal cord, lymph node, mandible, maxilla, membranous bone, mesenteric lymph nodes, popliteal artery, right coronary artery, right lung lobe, spleen, thymus, tibial arteries, tibial nerve
RNA expression pattern · 20
TRAF1 → appendix, ascending aorta, blood, Dermatocranium, Descending thoracic aorta, granulocyte, left coronary artery, lumbar subsegment of spinal cord, lymph node, mandible, maxilla, membranous bone, mesenteric lymph nodes, popliteal artery, right coronary artery, right lung lobe, spleen, thymus, tibial arteries, tibial nerve
Gene ontology · 16
TRAF1 → apoptotic process, cytoplasm, cytosol, identical protein binding, positive regulation of NF-kappaB transcription factor activity, protein binding, protein-containing complex, protein-containing complex assembly, regulation of apoptotic process, regulation of extrinsic apoptotic signaling pathway, regulation of tumor necrosis factor-mediated signaling pathway, signal transduction, thioesterase binding, tumor necrosis factor receptor binding, ubiquitin protein ligase binding, zinc ion binding
related to Function · 16
TRAF1 → EBV, Epstein-Barr, IAP, LMP1, LMP1-mediated, MAPK8/JNK, NEMO, NF-kappaB, The, This, TLR, TNF, TNF-alpha-mediated, TNFR, TRAF, TRAF2
related to Interactions · 10
TRAF1 → Baculoviral IAP, BIRC2, Caspase, CFLAR, HIVEP3, RANKTNFAIP3, RBCK1, RNF31, SHARPIN, TRAF
Band · 2
TRAF1 → 2|2 B, 9q33.2
Chr. · 2
TRAF1 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
TRAF1 → 120,929,173 bp, 34,851,784 bp
Aliases · 1
TRAF1 → TRAF1, EBI6, MGC:10353, TNF receptor associated factor 1
Available structures · 1
TRAF1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp gene chr human band factor chromosome tnf location traf receptor traf2 mouse complex signal transduction function tnfr receptors

TRAF1 relationships Subject–Predicate–Object triples

TTTA extracted 105 structured relationships around TRAF1. Examples in this analysis include TRAF1 → Aliases → TRAF1, EBI6, MGC:10353, TNF receptor associated factor 1 and TRAF1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TRAF1AliasesTRAF1, EBI6, MGC:10353, TNF receptor associated factor 11.00infobox
TRAF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3M0D1.00infobox
TRAF1Band9q33.21.00infobox
TRAF1Band2|2 B1.00infobox
TRAF1Bgeegranulocyte1.00infobox
TRAF1Bgeeright coronary artery1.00infobox
TRAF1BgeeDescending thoracic aorta1.00infobox
TRAF1Bgeeascending aorta1.00infobox
TRAF1Bgeelymph node1.00infobox
TRAF1Bgeepopliteal artery1.00infobox
TRAF1Bgeetibial arteries1.00infobox
TRAF1Bgeeleft coronary artery1.00infobox
TRAF1Bgeeappendix1.00infobox
TRAF1Bgeetibial nerve1.00infobox
TRAF1Bgeemesenteric lymph nodes1.00infobox
TRAF1Bgeespleen1.00infobox
TRAF1Bgeemembranous bone1.00infobox
TRAF1BgeeDermatocranium1.00infobox
TRAF1Bgeeright lung lobe1.00infobox
TRAF1Bgeemandible1.00infobox
TRAF1Bgeemaxilla1.00infobox
TRAF1Bgeethymus1.00infobox
TRAF1Bgeeblood1.00infobox
TRAF1Bgeelumbar subsegment of spinal cord1.00infobox
TRAF1BioGPSMore reference expression data1.00infobox
TRAF1Chr.Chromosome 9 (human)1.00infobox
TRAF1Chr.Chromosome 2 (mouse)1.00infobox
TRAF1DatabasesNCBI: entry; OMA: entry1.00infobox
TRAF1End120,929,173 bp1.00infobox
TRAF1End34,851,784 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TRAF1 bring nearby vocabulary together. In this analysis, examples include Traf, Also and Iap. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Complex
    • Traf2
    • Tnf
    • Traf
    • Traf1
    • Ebv
    • Encoded
    • Expression
    • Family
    • Iap
    • Interact
    • Nf-kappab
  • gene
    • Location
    • Chromosome
    • Human
    • Tnf
    • Associated
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Receptor
    • Search
  • baculoviral iap repeat-containing protein 3
    • Traf2
    • Complex
    • Tnf
    • Traf
    • Interact
    • Traf1
    • Ebv
    • Encoded
    • Expression
    • Family
    • Iap
    • Nf-kappab
  • traf interacting protein
    • Transduction
    • Interact
    • Proteins
    • Complex
    • Traf2
    • Receptors
    • Tnf
    • Traf
    • Traf1
    • Ebv
    • Encoded
    • Expression
  • function
    • Associated
    • Receptor
    • Search
    • Location
    • Chromosome
    • Gene
    • Human
    • Tnf
    • Bp
    • Chr
    • End
    • Expression
  • traf2
    • Iap
    • Complex
    • Protein
    • Also
    • Interact
    • Nf-kappab
    • Receptors
    • Tnf
    • Traf
    • Traf1
  • interact
    • Traf
    • Proteins
    • Protein
    • Receptors
    • Signal
    • Tnfr
    • Traf2
    • Transduction
    • Traf1
  • TRAF1
    • Traf
    • Also
    • Iap
    • Interact
    • Tnfr
    • Traf2
    • Transduction

Connections between topic areas Semantic bridges

For TRAF1, one of the stronger structural bridges in this analysis connects TRAF1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TRAF1Interactions · splits 6 ⟂ 14
TRAF1Overview · splits 17 ⟂ 3

Map overview Semantic statistics

TRAF1

Nodes20
Edges19
Triples105
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around TRAF1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TRAF1 · EN edition · Analysis: TopicsToTalkAbout

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