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NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded by the IKBKG gene. NEMO is a subunit of the IκB kinase complex that activates NF-κB. The human gene for IKBKG is located on the chromosome band Xq28. Multiple transcript variants encoding different…
The analysis highlights Music, Regions and Measurement as prominent areas in the source structure around IKBKG.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around IKBKG shows recurring relationship patterns in the source. For example, IKBKG → anoikis, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, apoptotic process, cellular response to DNA damage stimulus, cytoplasm, cytosol, establishment of vesicle localization, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, identical protein binding, IkappaB kinase complex, immune response, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, intracellular anatomical structure, JNK cascade, K63-linked polyubiquitin modification-dependent protein binding, linear polyubiquitin binding, metal ion binding Another extracted example is IKBKG → blood, cardiac muscle tissue of left ventricle, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, granulocyte, left adrenal cortex, left adrenal gland, left lobe of liver, lumbar subsegment of spinal cord, monocyte, neural layer of retina, right adrenal cortex, right lobe of liver, right lung, spleen, stroma of bone marrow, transitional epithelium of urinary bladder, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
nemo nf-κb gene peptide nbd human complex subunit band kinase bp chromosome chr binding ikk ikk-γ mouse activity activation inflammation
TTTA extracted 135 structured relationships around IKBKG. Examples in this analysis include IKBKG → Aliases → IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKKAP1, IKKG, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,… and IKBKG → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JVX, 2JVY, 3BRT, 3BRV, 3CL3, 3FX0, 4BWN, 5AAY. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IKBKG | Aliases | IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKKAP1, IKKG, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,… | 1.00 | infobox |
| IKBKG | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JVX, 2JVY, 3BRT, 3BRV, 3CL3, 3FX0, 4BWN, 5AAY | 1.00 | infobox |
| IKBKG | Band | Xq28 | 1.00 | infobox |
| IKBKG | Band | X|X A7.3 | 1.00 | infobox |
| IKBKG | Bgee | granulocyte | 1.00 | infobox |
| IKBKG | Bgee | blood | 1.00 | infobox |
| IKBKG | Bgee | spleen | 1.00 | infobox |
| IKBKG | Bgee | right lobe of liver | 1.00 | infobox |
| IKBKG | Bgee | upper lobe of left lung | 1.00 | infobox |
| IKBKG | Bgee | right adrenal cortex | 1.00 | infobox |
| IKBKG | Bgee | left adrenal gland | 1.00 | infobox |
| IKBKG | Bgee | left adrenal cortex | 1.00 | infobox |
| IKBKG | Bgee | monocyte | 1.00 | infobox |
| IKBKG | Bgee | right lung | 1.00 | infobox |
| IKBKG | Bgee | left lobe of liver | 1.00 | infobox |
| IKBKG | Bgee | neural layer of retina | 1.00 | infobox |
| IKBKG | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| IKBKG | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| IKBKG | Bgee | lumbar subsegment of spinal cord | 1.00 | infobox |
| IKBKG | Bgee | transitional epithelium of urinary bladder | 1.00 | infobox |
| IKBKG | Bgee | stroma of bone marrow | 1.00 | infobox |
| IKBKG | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| IKBKG | BioGPS | More reference expression data | 1.00 | infobox |
| IKBKG | Chr. | X chromosome (human) | 1.00 | infobox |
| IKBKG | Chr. | X chromosome (mouse) | 1.00 | infobox |
| IKBKG | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IKBKG | End | 154,565,046 bp | 1.00 | infobox |
| IKBKG | End | 73,497,460 bp | 1.00 | infobox |
| IKBKG | Ensembl | ENSG00000269335 | 1.00 | infobox |
| IKBKG | Entrez | 8517 | 1.00 | infobox |
The concept neighborhoods around IKBKG bring nearby vocabulary together. In this analysis, examples include Gene, Human and Inhibitor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IKBKG, one of the stronger structural bridges in this analysis connects IKBKG with As a drug target. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IKBKG to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Music, Regions & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IKBKG · EN edition · Analysis: TopicsToTalkAbout