IKBKG

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Explore the main themes, entities and connections around IKBKG. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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As a drug target

Signal transduction cascade Phosphorylation IκBα P105 RELA

27 related topics

Interactions

Interact BCL10 CDC37 CHUK IKK2

12 related topics

Clinical significance

Incontinentia pigmenti Hypohidrotic ectodermal dysplasia TNF-alpha Apoptosis NEMO deficiency syndrome

5 related topics

Overview

Protein Gene IκB kinase NF-κB Xq28

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKKAP1, IKKG, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,…
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JVX, 2JVY, 3BRT, 3BRV, 3CL3, 3FX0, 4BWN, 5AAY
Band: Xq28 · X|X A7.3
Bgee: granulocyte · blood · spleen · right lobe of liver · upper lobe of left lung
BioGPS: More reference expression data
Chr.: X chromosome (human) · X chromosome (mouse)

Topics to explore

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Overview

Clinical significance

Interactions

Interact Protein-protein interaction
BCL10
CDC37
CHUK
IKK2
IRAK1
NCOA3 Nuclear receptor coactivator 3
PPM1B
TANK TANK (gene)
TNFAIP3
TRAF3IP2
TRAF6

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes54

Edges53

Triples135

Avg. degree1.96

Density0.037037

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

IKBKG

Top relations

Gene ontology · 49

IKBKG → anoikis, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, apoptotic process, cellular response to DNA damage stimulus, cytoplasm, cytosol, establishment of vesicle localization, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, identical protein binding, IkappaB kinase complex, immune response, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, intracellular anatomical structure, JNK cascade, K63-linked polyubiquitin modification-dependent protein binding, linear polyubiquitin binding, metal ion binding

Bgee · 18

IKBKG → blood, cardiac muscle tissue of left ventricle, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, granulocyte, left adrenal cortex, left adrenal gland, left lobe of liver, lumbar subsegment of spinal cord, monocyte, neural layer of retina, right adrenal cortex, right lobe of liver, right lung, spleen, stroma of bone marrow, transitional epithelium of urinary bladder, upper lobe of left lung

RNA expression pattern · 18

related to Interactions · 9

IKBKG → BCL10, CDC37, CHUK, IRAK1, NCOA3, PPM1B, TANK, TNFAIP3, TRAF3IP2

related to External links · 8

IKBKG → Anophthalmia, GeneReviews/NCBI/NIH/UW, GeneReviews/NIH/NCBI/UW, Incontinentia PigmentiOMIM IKBKG, Medicine Medical Subject Headings, MeSH, Microphthalmia Overview, National Library

related to Clinical significance · 7

IKBKG → Incontinentia Pigmenti, IP, Mutations, NF-κB, Since IKBKG, TNF-alpha, X-linked

Band · 2

IKBKG → Xq28, X|X A7.3

Chr. · 2

IKBKG → X chromosome (human), X chromosome (mouse)

End · 2

IKBKG → 154,565,046 bp, 73,497,460 bp

Aliases · 1

IKBKG → IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKKAP1, IKKG, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,…

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nemo nf-κb gene peptide nbd human complex subunit band kinase bp chromosome chr binding ikk ikk-γ mouse activity activation inflammation

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
IKBKG	Aliases	IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKKAP1, IKKG, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma,…	1.00	infobox
IKBKG	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JVX, 2JVY, 3BRT, 3BRV, 3CL3, 3FX0, 4BWN, 5AAY	1.00	infobox
IKBKG	Band	Xq28	1.00	infobox
IKBKG	Band	X\|X A7.3	1.00	infobox
IKBKG	Bgee	granulocyte	1.00	infobox
IKBKG	Bgee	blood	1.00	infobox
IKBKG	Bgee	spleen	1.00	infobox
IKBKG	Bgee	right lobe of liver	1.00	infobox
IKBKG	Bgee	upper lobe of left lung	1.00	infobox
IKBKG	Bgee	right adrenal cortex	1.00	infobox
IKBKG	Bgee	left adrenal gland	1.00	infobox
IKBKG	Bgee	left adrenal cortex	1.00	infobox
IKBKG	Bgee	monocyte	1.00	infobox
IKBKG	Bgee	right lung	1.00	infobox
IKBKG	Bgee	left lobe of liver	1.00	infobox
IKBKG	Bgee	neural layer of retina	1.00	infobox
IKBKG	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
IKBKG	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
IKBKG	Bgee	lumbar subsegment of spinal cord	1.00	infobox
IKBKG	Bgee	transitional epithelium of urinary bladder	1.00	infobox
IKBKG	Bgee	stroma of bone marrow	1.00	infobox
IKBKG	Bgee	cardiac muscle tissue of left ventricle	1.00	infobox
IKBKG	BioGPS	More reference expression data	1.00	infobox
IKBKG	Chr.	X chromosome (human)	1.00	infobox
IKBKG	Chr.	X chromosome (mouse)	1.00	infobox
IKBKG	Databases	NCBI: entry; OMA: entry	1.00	infobox
IKBKG	End	154,565,046 bp	1.00	infobox
IKBKG	End	73,497,460 bp	1.00	infobox
IKBKG	Ensembl	ENSG00000269335	1.00	infobox
IKBKG	Entrez	8517	1.00	infobox

Related concept clusters Concept neighborhoods

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Connections between topic areas Semantic bridges

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