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HOXA9: Interactions, Function & Clinical significance

Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene.

Language: English [EN]
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HOXA9 topic overview

The analysis highlights Interactions, Function and Clinical significance as prominent areas in the source structure around HOXA9.

Related topics
57
Source areas
4
Connected nodes
61
Extracted relationships
81
Concept neighborhoods
20
Bridge connections
61

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 23 topics
Function · 15 topics
Clinical significance · 12 topics
Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
Hoxa9lRGD1310001homeobox A9
Band
4q24 · 6 B3|6 25.4 cM
Chr.
Chromosome 4 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry
End
81,326,358 bp · 52,208,069 bp
Ensembl
ENSRNOG00000064322

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HOXA9 connects Entity context

The extracted context around HOXA9 shows recurring relationship patterns in the source. For example, HOXA9 → Adult, Furthermore, However, HSC, HSCs, In, It, Most, The, There, This, Throughout Another extracted example is HOXA9 → AML, However, HSCs, NUP98, NUP98-HOXA9, Ordinarily, The, The HOXA9, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

HOXA9

Top relations

related to Expression in adult, fetal and embryonic stages · 12
HOXA9 → Adult, Furthermore, However, HSC, HSCs, In, It, Most, The, There, This, Throughout
related to Role in acute myeloid leukemia · 9
HOXA9 → AML, However, HSCs, NUP98, NUP98-HOXA9, Ordinarily, The, The HOXA9, This
Gene ontology · 8
HOXA9 → DNA binding, multicellular organism development, nucleus, prostate gland development, regulation of transcription, DNA-templated, response to testosterone, sequence-specific DNA binding, transcription, DNA-templated
related to Role in hematopoiesis · 8
HOXA9 → As HOXA9, ErythronDB, HOXA, HOXA7, HSCs, Indeed, The, This
related to Morphology alteration · 7
HOXA9 → AML, By, HSC, NUP98-HOXA9, Proerythroblasts, These, Thus
related to External links · 6
HOXA9 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Pure erythroid leukemia · 6
HOXA9 → AML, Furthermore, Hence, In, One, There
Band · 2
HOXA9 → 4q24, 6 B3|6 25.4 cM
Chr. · 2
HOXA9 → Chromosome 4 (human), Chromosome 6 (mouse)
End · 2
HOXA9 → 52,208,069 bp, 81,326,358 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

expression gene erythroid differentiation myeloid oncogene stages genes adult hscs chromosome development erythrocyte human cells bp fetal ovarian leukemia transcription

HOXA9 relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around HOXA9. Examples in this analysis include HOXA9 → Aliases → Hoxa9lRGD1310001homeobox A9 and HOXA9 → Band → 4q24. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HOXA9AliasesHoxa9lRGD1310001homeobox A91.00infobox
HOXA9Band4q241.00infobox
HOXA9Band6 B3|6 25.4 cM1.00infobox
HOXA9Chr.Chromosome 4 (human)1.00infobox
HOXA9Chr.Chromosome 6 (mouse)1.00infobox
HOXA9DatabasesNCBI: entry; OMA: entry1.00infobox
HOXA9End81,326,358 bp1.00infobox
HOXA9End52,208,069 bp1.00infobox
HOXA9EnsemblENSRNOG000000643221.00infobox
HOXA9Entrez2970991.00infobox
HOXA9External IDsMGI: 96180; GeneCards:1.00infobox
HOXA9Gene location (Human)Gene location (Human)Chr.Chromosome 4 (human)Band4q24Start81,323,382 bpEnd81,326,358 bp1.00infobox
HOXA9Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 6 (mouse)Band6 B3|6 25.4 cMStart52,200,080 bpEnd52,208,069 bp1.00infobox
HOXA9Gene ontologyDNA binding1.00infobox
HOXA9Gene ontologysequence-specific DNA binding1.00infobox
HOXA9Gene ontologynucleus1.00infobox
HOXA9Gene ontologytranscription, DNA-templated1.00infobox
HOXA9Gene ontologyregulation of transcription, DNA-templated1.00infobox
HOXA9Gene ontologymulticellular organism development1.00infobox
HOXA9Gene ontologyprostate gland development1.00infobox
HOXA9Gene ontologyresponse to testosterone1.00infobox
HOXA9Location (UCSC)Chr 4: 81.32 – 81.33 Mb1.00infobox
HOXA9OrthologsOrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez29709915405EnsemblENSRNOG00000064322ENSMUSG00000038227UniProtD3ZSU5P09631RefSeq (mRNA)XM_003752183 XM_039108678NM…1.00infobox
HOXA9RefSeq (mRNA)XM_003752183 XM_0391086781.00infobox
HOXA9RefSeq (protein)XP_008761169 XP_017448488 XP_017458295 XP_017458296 XP_003749799 XP_017448487 XP_003752231 XP_017457951 XP_0389646061.00infobox
HOXA9SpeciesHuman1.00infobox
HOXA9UniProtD3ZSU51.00infobox
HOXA9is acandidate for one of the genes responsible for these morphological differences between the erythrocyte lineages0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around HOXA9 bring nearby vocabulary together. In this analysis, examples include Expression, Erythrocyte and Lineage. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HOXA9
    • Expression
    • Erythrocyte
    • Lineage
    • Genes
    • Hscs
    • Protein
    • Erythroid
    • Ovarian
    • Cells
    • Myeloid
    • Differentiation
    • Stages
  • hoxa9
    • Expression
    • Erythrocyte
    • Lineage
    • Genes
    • Hscs
    • Protein
    • Erythroid
    • Ovarian
    • Cells
    • Myeloid
    • Differentiation
    • Stages
  • gene
    • Chromosome
    • Nup98
    • Expression
    • Bp
    • Chr
    • Human
    • Transcription
    • Hoxa9
    • Myeloid
    • Band
    • Homeobox
    • Protein
  • homeobox genes
    • Protein
    • Human
    • Transcription
    • Faaborg
    • Al
    • Et
    • Hoxa9
    • Band
    • Gene
    • Found
    • However
    • Bp
  • differentiation
    • Hscs
    • Oncogene
    • Lineage
    • May
    • Found
    • Transcription
    • Hoxa9
    • Erythroid
    • Study
    • Cells
    • Myeloid
    • Gene
  • chromosome 7
    • Bp
    • Chr
    • Gene
    • Human
    • Band
    • Nup98
    • Transcription
    • Differentiation
    • Expression
    • Homeobox
    • May
    • Protein
  • chromosome 11
    • Bp
    • Chr
    • Gene
    • Human
    • Band
    • Nup98
    • Transcription
    • Differentiation
    • Expression
    • Homeobox
    • May
    • Protein
  • gene translocation
    • Chromosome
    • Nup98
    • Expression
    • Bp
    • Chr
    • Human
    • Transcription
    • Hoxa9
    • Myeloid
    • Band
    • Homeobox
    • Protein

Connections between topic areas Semantic bridges

For HOXA9, one of the stronger structural bridges in this analysis connects HOXA9 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HOXA9Interactions · splits 38 ⟂ 24
HOXA9Function · splits 46 ⟂ 16
HOXA9Clinical significance · splits 49 ⟂ 13
HOXA9Overview · splits 54 ⟂ 8

Map overview Semantic statistics

HOXA9

Nodes62
Edges61
Triples81
Avg. degree1.97
Density0.032258
Components1

Source & methodology

TTTA analyzes the structure around HOXA9 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HOXA9 · EN edition · Analysis: TopicsToTalkAbout

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