Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

MYD88

Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene. originally discovered in the laboratory of Dan A. Liebermann (Lord et al. Oncogene 1990) as a Myeloid differentiation primary response gene.

Function, Interactions & Gene polymorphisms

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around MYD88. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MYD88, MYD88D, myeloid differentiation primary response 88, innate immune signal transduction adaptor, MYD88 innate immune signal transduction adaptor, IMD68
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JS7, 2Z5V, 3MOP, 4DOM, 4EO7
Band
3p22.2 · 9 F3|9 71.33 cM
Bgee
white blood cell · mononuclear cell · monocyte · granulocyte · blood
BioGPS
More reference expression data
Chr.
Chromosome 3 (human) · Chromosome 9 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Gene polymorphisms

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

MYD88

Nodes43
Edges42
Triples117
Avg. degree1.95
Density0.046512
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

MYD88

Top relations

Gene ontology · 41
MYD88 → 3'-UTR-mediated mRNA stabilization, apoptotic process, cell surface receptor signaling pathway, cellular response to mechanical stimulus, cellular response to oxidised low-density lipoprotein particle stimulus, cytoplasm, cytosol, death receptor binding, defense response to bacterium, defense response to Gram-positive bacterium, endosome membrane, identical protein binding, immune system process, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, MyD88-dependent toll-like receptor signaling pathway, negative regulation of apoptotic process, nucleus, phagocytosis
Bgee · 18
MYD88 → ankle joint, blood, duodenum, esophagus, gingival epithelium, granulocyte, lip, monocyte, mononuclear cell, mucosa of ileum, nasal epithelium, palpebral conjunctiva, periodontal fiber, right lung lobe, stroma of bone marrow, tibiofemoral joint, uterus, white blood cell
RNA expression pattern · 18
MYD88 → ankle joint, blood, duodenum, esophagus, gingival epithelium, granulocyte, lip, monocyte, mononuclear cell, mucosa of ileum, nasal epithelium, palpebral conjunctiva, periodontal fiber, right lung lobe, stroma of bone marrow, tibiofemoral joint, uterus, white blood cell
related to Function · 8
MYD88 → DAMPs, In, PAMPs, Pathogen-associated, PRR, The MYD88, TLRs, Toll-like
related to External links · 4
MYD88 → Medicine Medical Subject Headings, MeSH, National Library, Protein
related to Gene polymorphisms · 3
MYD88 → For, SNPs, Various
Band · 2
MYD88 → 3p22.2, 9 F3|9 71.33 cM
Chr. · 2
MYD88 → Chromosome 3 (human), Chromosome 9 (mouse)
End · 2
MYD88 → 119,170,477 bp, 38,143,022 bp
related to Interactions · 2
MYD88 → IRAC1TLR, IRAK1IRAK2Interleukin

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein human bp tlrs chr band immune response chromosome myeloid differentiation primary innate mouse cell location function various tlr3

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MYD88AliasesMYD88, MYD88D, myeloid differentiation primary response 88, innate immune signal transduction adaptor, MYD88 innate immune signal transduction adaptor, IMD681.00infobox
MYD88Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JS7, 2Z5V, 3MOP, 4DOM, 4EO71.00infobox
MYD88Band3p22.21.00infobox
MYD88Band9 F3|9 71.33 cM1.00infobox
MYD88Bgeewhite blood cell1.00infobox
MYD88Bgeemononuclear cell1.00infobox
MYD88Bgeemonocyte1.00infobox
MYD88Bgeegranulocyte1.00infobox
MYD88Bgeeblood1.00infobox
MYD88Bgeegingival epithelium1.00infobox
MYD88Bgeemucosa of ileum1.00infobox
MYD88Bgeeperiodontal fiber1.00infobox
MYD88Bgeenasal epithelium1.00infobox
MYD88Bgeepalpebral conjunctiva1.00infobox
MYD88Bgeestroma of bone marrow1.00infobox
MYD88Bgeeright lung lobe1.00infobox
MYD88Bgeelip1.00infobox
MYD88Bgeeankle joint1.00infobox
MYD88Bgeeuterus1.00infobox
MYD88Bgeeesophagus1.00infobox
MYD88Bgeetibiofemoral joint1.00infobox
MYD88Bgeeduodenum1.00infobox
MYD88BioGPSMore reference expression data1.00infobox
MYD88Chr.Chromosome 3 (human)1.00infobox
MYD88Chr.Chromosome 9 (mouse)1.00infobox
MYD88DatabasesNCBI: entry; OMA: entry1.00infobox
MYD88End38,143,022 bp1.00infobox
MYD88End119,170,477 bp1.00infobox
MYD88EnsemblENSG000001729361.00infobox
MYD88Entrez46151.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.