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Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene. originally discovered in the laboratory of Dan A. Liebermann (Lord et al. Oncogene 1990) as a Myeloid differentiation primary response gene.
The analysis highlights Function, Interactions and Gene polymorphisms as prominent areas in the source structure around MYD88.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MYD88 shows recurring relationship patterns in the source. For example, MYD88 → 3'-UTR-mediated mRNA stabilization, apoptotic process, cell surface receptor signaling pathway, cellular response to mechanical stimulus, cellular response to oxidised low-density lipoprotein particle stimulus, cytoplasm, cytosol, death receptor binding, defense response to bacterium, defense response to Gram-positive bacterium, endosome membrane, identical protein binding, immune system process, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, MyD88-dependent toll-like receptor signaling pathway, negative regulation of apoptotic process, nucleus, phagocytosis Another extracted example is MYD88 → ankle joint, blood, duodenum, esophagus, gingival epithelium, granulocyte, lip, monocyte, mononuclear cell, mucosa of ileum, nasal epithelium, palpebral conjunctiva, periodontal fiber, right lung lobe, stroma of bone marrow, tibiofemoral joint, uterus, white blood cell. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene protein human bp tlrs chr band immune response chromosome myeloid differentiation primary innate mouse cell location function various tlr3
TTTA extracted 117 structured relationships around MYD88. Examples in this analysis include MYD88 → Aliases → MYD88, MYD88D, myeloid differentiation primary response 88, innate immune signal transduction adaptor, MYD88 innate immune signal transduction adaptor, IMD68 and MYD88 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JS7, 2Z5V, 3MOP, 4DOM, 4EO7. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MYD88 | Aliases | MYD88, MYD88D, myeloid differentiation primary response 88, innate immune signal transduction adaptor, MYD88 innate immune signal transduction adaptor, IMD68 | 1.00 | infobox |
| MYD88 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JS7, 2Z5V, 3MOP, 4DOM, 4EO7 | 1.00 | infobox |
| MYD88 | Band | 3p22.2 | 1.00 | infobox |
| MYD88 | Band | 9 F3|9 71.33 cM | 1.00 | infobox |
| MYD88 | Bgee | white blood cell | 1.00 | infobox |
| MYD88 | Bgee | mononuclear cell | 1.00 | infobox |
| MYD88 | Bgee | monocyte | 1.00 | infobox |
| MYD88 | Bgee | granulocyte | 1.00 | infobox |
| MYD88 | Bgee | blood | 1.00 | infobox |
| MYD88 | Bgee | gingival epithelium | 1.00 | infobox |
| MYD88 | Bgee | mucosa of ileum | 1.00 | infobox |
| MYD88 | Bgee | periodontal fiber | 1.00 | infobox |
| MYD88 | Bgee | nasal epithelium | 1.00 | infobox |
| MYD88 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| MYD88 | Bgee | stroma of bone marrow | 1.00 | infobox |
| MYD88 | Bgee | right lung lobe | 1.00 | infobox |
| MYD88 | Bgee | lip | 1.00 | infobox |
| MYD88 | Bgee | ankle joint | 1.00 | infobox |
| MYD88 | Bgee | uterus | 1.00 | infobox |
| MYD88 | Bgee | esophagus | 1.00 | infobox |
| MYD88 | Bgee | tibiofemoral joint | 1.00 | infobox |
| MYD88 | Bgee | duodenum | 1.00 | infobox |
| MYD88 | BioGPS | More reference expression data | 1.00 | infobox |
| MYD88 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| MYD88 | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| MYD88 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MYD88 | End | 38,143,022 bp | 1.00 | infobox |
| MYD88 | End | 119,170,477 bp | 1.00 | infobox |
| MYD88 | Ensembl | ENSG00000172936 | 1.00 | infobox |
| MYD88 | Entrez | 4615 | 1.00 | infobox |
The concept neighborhoods around MYD88 bring nearby vocabulary together. In this analysis, examples include Protein, Immune and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MYD88, one of the stronger structural bridges in this analysis connects MYD88 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MYD88 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Gene polymorphisms, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MYD88 · EN edition · Analysis: TopicsToTalkAbout