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Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions in a variety of cellular pathways related to both cell survival and death. In terms of cell death, RIPK1 plays a role in apoptosis, necroptosis, and PANoptosis. Some of the cell survival pathways RIPK1 participates in include NF-κB, Akt, and JNK.
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cell complex death kinase activation survival protein nf-kb ripk3 domain necroptosis receptor gene apoptosis also bp activity chromosome traf2 signalling
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| RIPK1 | 2.7.11.1 | ↗ | 1.00 | infobox |
| RIPK1 | Aliases | RIPK1, RIP, RIP1, RIP-1, receptor interacting serine/threonine kinase 1, IMD57, AIEFL | 1.00 | infobox |
| RIPK1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ITH, 4ITI, 4ITJ, 4NEU, 5HX6 | 1.00 | infobox |
| RIPK1 | Band | 6p25.2 | 1.00 | infobox |
| RIPK1 | Band | 13 A3.3|13 14.01 cM | 1.00 | infobox |
| RIPK1 | Bgee | granulocyte | 1.00 | infobox |
| RIPK1 | Bgee | sural nerve | 1.00 | infobox |
| RIPK1 | Bgee | right lobe of liver | 1.00 | infobox |
| RIPK1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| RIPK1 | Bgee | gastric mucosa | 1.00 | infobox |
| RIPK1 | Bgee | Achilles tendon | 1.00 | infobox |
| RIPK1 | Bgee | right coronary artery | 1.00 | infobox |
| RIPK1 | Bgee | skin of abdomen | 1.00 | infobox |
| RIPK1 | Bgee | skin of leg | 1.00 | infobox |
| RIPK1 | Bgee | apex of heart | 1.00 | infobox |
| RIPK1 | Bgee | renal corpuscle | 1.00 | infobox |
| RIPK1 | Bgee | Paneth cell | 1.00 | infobox |
| RIPK1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| RIPK1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| RIPK1 | Bgee | left lobe of liver | 1.00 | infobox |
| RIPK1 | Bgee | epithelium of stomach | 1.00 | infobox |
| RIPK1 | Bgee | jejunum | 1.00 | infobox |
| RIPK1 | Bgee | conjunctival fornix | 1.00 | infobox |
| RIPK1 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| RIPK1 | BioGPS | More reference expression data | 1.00 | infobox |
| RIPK1 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| RIPK1 | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| RIPK1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| RIPK1 | End | 3,115,187 bp | 1.00 | infobox |
| RIPK1 | End | 34,221,130 bp | 1.00 | infobox |
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