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ETS1

Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. The protein encoded by this gene belongs to the ETS transcription factor family.

Interaction with DNA repair promoters and proteins, Interactions & Knockout mice

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Interaction with DNA repair promoters and proteins

15 related topics

Interactions

4 related topics

Knockout mice

2 related topics

Function

1 related topics

Key facts & relationships

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Aliases
ETS1, ETS-1, EWSR2, p54, c-ets-1, ETS proto-oncogene 1, transcription factor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z,…
Band
11q24.3 · 9 A4|9 17.97 cM
Bgee
visceral pleura · parietal pleura · tibia · epithelium of nasopharynx · lower lobe of lung
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)

Topics to explore

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Overview

Function

Knockout mice

Interactions

Interaction with DNA repair promoters and proteins

Advanced semantic analysis

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Map overview Semantic statistics

ETS1

Nodes31
Edges30
Triples222
Avg. degree1.94
Density0.064516
Components1

How this topic connects Entity context

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ETS1

Top relations

Gene ontology · 56
ETS1 → angiogenesis involved in wound healing, cell differentiation, cell motility, cellular response to hydrogen peroxide, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, estrous cycle, female pregnancy, histone acetyltransferase binding, hypothalamus development, identical protein binding, immune response, immune system process, negative regulation of cell cycle, negative regulation of cell population proliferation, negative regulation of inflammatory response, nucleoplasm
related to Function · 30
ETS1 → AGGAAG, AP1, C-terminal, CGGAAG, ChIP-Seq, Contrary, DNA, Erk2, ETS, Ets/AP1, Ets1-responsive GGAA/T, First, For, GGAA/T, However, If, It, Many Ras, On, Phosphorylation
Bgee · 20
ETS1 → atrioventricular valve, atrium, blood, endocardial cushion, epithelium of colon, epithelium of nasopharynx, Gonadal ridge, left lung lobe, lower lobe of lung, lymph node, mesenteric lymph nodes, parietal pleura, pericardium, right lung lobe, spleen, superficial temporal artery, thymus, tibia, vena cava, visceral pleura
RNA expression pattern · 20
ETS1 → atrioventricular valve, atrium, blood, endocardial cushion, epithelium of colon, epithelium of nasopharynx, Gonadal ridge, left lung lobe, lower lobe of lung, lymph node, mesenteric lymph nodes, parietal pleura, pericardium, right lung lobe, spleen, superficial temporal artery, thymus, tibia, vena cava, visceral pleura
related to DNA repair protein interactions · 17
ETS1 → Active PARP1, ADP-ribosylation, As, DNA, DNA-dependent, DNA-PK, DNA-PKcs, In, Ku, Ku70, Ku80, Legrand, PARP1, Such, The Ku80, XRCC5, XRCC6
related to Interactions · 15
ETS1 → Acetyltransferases CBP, Also, AP1, C-terminal, Death-associated, Pax5, Runx1, STAT5, TFE3, Their, TTRAP, UBE2I, USF1, VDR, When Ets1
related to DNA repair promoters · 14
ETS1 → As, BARD1, CpG, DNA, ERCC1, If, Increased ETS1, MUTYH, PARP1, RNA, The, These, Wilson, XPA
related to Knockout mice · 10
ETS1 → Although Ets1, Ets, IL-2, In CD4/CD8, T-cell, Th1, Th17, Th2, There, Treg
related to External links · 7
ETS1 → Drosophila, Medicine, Medicine Medical Subject Headings, MeSH, National Library, The Interactive FlyFactorBookETS1 This, United States National Library
related to Clinical significance · 6
ETS1 → European, Meta-analyses, Mmps, SNPs, Th17, This

Important terminology Word statistics

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Important terminology

dna protein parp1 gene transcription ets bp binding human factor repair expression chr band promoter bind domain sites interacts chromosome

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ETS1AliasesETS1, ETS-1, EWSR2, p54, c-ets-1, ETS proto-oncogene 1, transcription factor1.00infobox
ETS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z,…1.00infobox
ETS1Band11q24.31.00infobox
ETS1Band9 A4|9 17.97 cM1.00infobox
ETS1Bgeevisceral pleura1.00infobox
ETS1Bgeeparietal pleura1.00infobox
ETS1Bgeetibia1.00infobox
ETS1Bgeeepithelium of nasopharynx1.00infobox
ETS1Bgeelower lobe of lung1.00infobox
ETS1Bgeesuperficial temporal artery1.00infobox
ETS1Bgeeepithelium of colon1.00infobox
ETS1Bgeepericardium1.00infobox
ETS1Bgeevena cava1.00infobox
ETS1Bgeelymph node1.00infobox
ETS1Bgeeleft lung lobe1.00infobox
ETS1Bgeethymus1.00infobox
ETS1Bgeemesenteric lymph nodes1.00infobox
ETS1Bgeeblood1.00infobox
ETS1Bgeespleen1.00infobox
ETS1BgeeGonadal ridge1.00infobox
ETS1Bgeeright lung lobe1.00infobox
ETS1Bgeeatrium1.00infobox
ETS1Bgeeatrioventricular valve1.00infobox
ETS1Bgeeendocardial cushion1.00infobox
ETS1BioGPSMore reference expression data1.00infobox
ETS1Chr.Chromosome 11 (human)1.00infobox
ETS1Chr.Chromosome 9 (mouse)1.00infobox
ETS1DatabasesNCBI: entry; OMA: entry1.00infobox
ETS1End128,587,558 bp1.00infobox
ETS1End32,757,820 bp1.00infobox

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