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2C-E: History & Applications

2C-E, also known as 4-ethyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally.

Language: English [EN]
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2C-E topic overview

The analysis highlights History and Applications as prominent areas in the source structure around 2C-E.

Related topics
69
Source areas
7
Connected nodes
76
Extracted relationships
86
Concept neighborhoods
23
Bridge connections
76

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 23 topics
Use and effects · 18 topics
Interactions · 11 topics
Chemistry · 8 topics
Side effects · 6 topics
Pharmacology · 2 topics
History · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
None
CAS Number
71539-34-9 Y
ChEMBL
ChEMBL124063 Y
ChemSpider
21106222 Y
CompTox Dashboard (EPA)
DTXSID40221772

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Use and effects

Side effects

Interactions

Pharmacology

Chemistry

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How 2C-E connects Entity context

The extracted context around 2C-E shows recurring relationship patterns in the source. For example, 2C-E → Bluelight2C-E, Dandy, Erowid2C-E, Isomer Design2C-E, Isomer DesignThe Big, Myron, PiHKAL, Psychedelic Exploration, Psychedelic Information, PsychonautWiki2C, Safety, Stolaroff, Thanatos To Eros, Thread, TripsitterA Most Remarkable Material, Years Another extracted example is 2C-E → Adverse, Alexander Shulgin, At, E's, Have Known, However, In, Loved, Phenethylamines, PiHKAL, Several, Shulgin, The, While. Use these groups to spot repeated connection types before inspecting the individual relationships.

2C-E

Top relations

related to External links · 16
2C-E → Bluelight2C-E, Dandy, Erowid2C-E, Isomer Design2C-E, Isomer DesignThe Big, Myron, PiHKAL, Psychedelic Exploration, Psychedelic Information, PsychonautWiki2C, Safety, Stolaroff, Thanatos To Eros, Thread, TripsitterA Most Remarkable Material, Years
has effect · 14
2C-E → Adverse, Alexander Shulgin, At, E's, Have Known, However, In, Loved, Phenethylamines, PiHKAL, Several, Shulgin, The, While
related to history · 9
2C-E → Alexander Shulgin, Have Known, It, Later, Loved, Phenethylamines, PiHKAL, Shulgin, Then
Legal status · 6
2C-E → BR: Class F2 (Prohibited psychotropics), CA: Schedule III, DE: Anlage I (Authorized scientific use only), NZ: Class C, UK: Class A, US: Schedule I
related to Analogues · 6
2C-E → Analogues, DMPEA, DOET, DOM, E-FLY, NBOMe
related to Interactions · 6
2C-E → MAO, MAO-A, MAO-B, MAOIs, Monoamine, This
is a · 4
2C-E → Class A controlled substance, controlled substance, controlled substance in China, Schedule I substance under the Food and Drug Administration Safety and Innovation Act of 2012
related to Pharmacodynamics · 4
2C-E → Activation, HT2, HT2A, It
related to Properties · 3
2C-E → Crystalline, HCl, Shulgin
3D model (JSmol) · 1
2C-E → Interactive image

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

shulgin drug psychedelic effects pihkal described serotonin also alexander known synthesis schedule receptor agonist controlled substance first book phenethylamine orally

2C-E relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around 2C-E. Examples in this analysis include 2C-E → 3D model (JSmol) → Interactive image and 2C-E → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
2C-E3D model (JSmol)Interactive image1.00infobox
2C-EATC codeNone1.00infobox
2C-ECAS Number71539-34-9 Y1.00infobox
2C-EChEMBLChEMBL124063 Y1.00infobox
2C-EChemSpider21106222 Y1.00infobox
2C-ECompTox Dashboard (EPA)DTXSID402217721.00infobox
2C-EDrug classSerotonin 5-HT2 receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen1.00infobox
2C-EDuration of action8–12 hours1.00infobox
2C-EECHA InfoCard100.221.0161.00infobox
2C-EFormulaC12H19NO21.00infobox
2C-ELegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
2C-ELegal statusCA: Schedule III1.00infobox
2C-ELegal statusDE: Anlage I (Authorized scientific use only)1.00infobox
2C-ELegal statusNZ: Class C1.00infobox
2C-ELegal statusUK: Class A1.00infobox
2C-ELegal statusUS: Schedule I1.00infobox
2C-EMolar mass209.289 g·mol−11.00infobox
2C-EOnset of action<2 hours1.00infobox
2C-EOther names4-Ethyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-ethylphenethylamine; 2C-DOET; 2C-DOEt; Aquarust1.00infobox
2C-EPubChem CID247292331.00infobox
2C-ERoutes of administrationOral1.00infobox
2C-ESolubility in water>70 mg/mL (20 °C)1.00infobox
2C-EUNIII190284UXX1.00infobox
2C-Eis acontrolled substance0.90text
2C-Eis aSchedule I substance under the Food and Drug Administration Safety and Innovation Act of 20120.90text
2C-Eis acontrolled substance in China0.90text
2C-Eis aClass A controlled substance0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around 2C-E bring nearby vocabulary together. In this analysis, examples include Drug, Effects and Controlled. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • 2C-E
    • Drug
    • Effects
    • Controlled
    • Schedule
    • Pihkal
    • Shulgin
    • Psychedelic
    • Act
    • Include
    • Substance
    • Described
    • Analogues
  • 2c-e
    • Drug
    • Effects
    • Controlled
    • Schedule
    • Pihkal
    • Shulgin
    • Psychedelic
    • Act
    • Include
    • Substance
    • Described
    • Analogues
  • psychedelic drug
    • Known
    • Schedule
    • Receptor
    • Serotonin
    • Synthesis
    • 5-ht2
    • 5-ht2a
    • Agonist
    • Analogues
    • Class
    • Loved
    • Phenethylamine
  • agonist
    • 5-ht2
    • Receptor
    • Serotonin
    • 5-ht2a
    • Duration
    • Hours
    • Analogues
    • Class
    • Loved
    • Mg
    • Onset
    • Orally
  • 5-ht2 receptors
    • Agonist
    • Receptor
    • Serotonin
    • 5-ht2a
    • Duration
    • Hours
    • Analogues
    • Class
    • Loved
    • Mg
    • Onset
    • Orally
  • 5-ht2a receptor
    • Serotonin
    • Receptor
    • Agonist
    • Duration
    • Hours
    • Psychedelic
    • Analogues
    • Class
    • Effects
    • Loved
    • Mg
    • Onset
  • alexander shulgin
    • Synthesized
    • Shulgin
    • Loved
    • Phenethylamines
    • Book
    • First
    • Known
    • Synthesis
    • Pihkal
    • Psychedelic
    • Described
    • Duration
  • united states
    • Class
    • Schedule
    • Substance
    • 4-ethyl-2
    • 5-dimethoxyphenethylamine
    • Duration
    • Hours
    • 5-ht2
    • 5-ht2a
    • Agonist
    • Analogues
    • Loved

Connections between topic areas Semantic bridges

For 2C-E, one of the stronger structural bridges in this analysis connects 2C-E with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
2C-EOverview · splits 53 ⟂ 24
2C-EUse and effects · splits 58 ⟂ 19
2C-EInteractions · splits 65 ⟂ 12
2C-EChemistry · splits 68 ⟂ 9
2C-ESide effects · splits 70 ⟂ 7
2C-EPharmacology · splits 74 ⟂ 3

Map overview Semantic statistics

2C-E

Nodes77
Edges76
Triples86
Avg. degree1.97
Density0.025974
Components1

Source & methodology

TTTA analyzes the structure around 2C-E to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — 2C-E · EN edition · Analysis: TopicsToTalkAbout

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