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Prochlorperazine

Prochlorperazine, formerly sold under the brand name Compazine among others, is a medication used to treat nausea, migraines, schizophrenia, psychosis and anxiety. It is a less preferred medication for anxiety. It may be taken by mouth, rectally, injection into a vein, or injection into a muscle.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AB04 (WHO)
Bioavailability
Unknown, but presumed substantial
CAS Number
58-38-8 Y
ChEBI
CHEBI:8435 Y

Topics to explore

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Overview

Medical uses

Side effects

Pharmacology

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Prochlorperazine

Nodes58
Edges57
Triples109
Avg. degree1.97
Density0.034483
Components1

How this topic connects Entity context

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Prochlorperazine

Top relations

related to Marketing · 39
Prochlorperazine → Ametil, Antinaus, As, Buccastem, Bukatel, Chlormeprazine, Chloropernazine, Compazine, Compro, Daolin, Dhaperazine, Emedrotec, Emetiral, Eminorm, Lotamin, Mitil, Mormal, Nautisol, Novamin, Novomit
has effect · 8
Prochlorperazine → Adverse, Drug Administration, NMS, Research, Sedation, Some, United States Food, Veterans Administration
related to Historical formulations · 8
Prochlorperazine → Darbazine, Eskatrol, French Laboratories, Kline, Smith, United States, Until, Vestil-A
related to External links · 5
Prochlorperazine → Archived, Drug Information Portal, June, Medicine, National Library
Legal status · 4
Prochlorperazine → AU: S4 (Prescription only) / S3, BR: Class C1 (Other controlled substances), UK: POM (Prescription only) / P, US: ℞-only
related to Society and culture · 4
Prochlorperazine → Australia, In, UK, United Kingdom
related to Pharmacology · 3
Prochlorperazine → D2, Hyperprolactinemia, This D2
related to Research · 3
Prochlorperazine → Alexza Pharmaceuticals, AT-001, Phase II
related to Synthesis · 3
Prochlorperazine → Chloro-10, Chloropropyl, The
related to Labyrinthitis · 2
Prochlorperazine → In, UK

Important terminology Word statistics

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Important terminology

effects medication may include side united antipsychotic used use states name injection migraine nausea symptoms action available commonly anxiety drug

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Prochlorperazine3D model (JSmol)Interactive image1.00infobox
ProchlorperazineAHFS/Drugs.comMonograph1.00infobox
ProchlorperazineATC codeN05AB04 (WHO)1.00infobox
ProchlorperazineBioavailabilityUnknown, but presumed substantial1.00infobox
ProchlorperazineCAS Number58-38-8 Y1.00infobox
ProchlorperazineChEBICHEBI:8435 Y1.00infobox
ProchlorperazineChEMBLChEMBL728 Y1.00infobox
ProchlorperazineChemSpider4748 Y1.00infobox
ProchlorperazineCompTox Dashboard (EPA)DTXSID70235141.00infobox
ProchlorperazineDrug classTypical antipsychotic1.00infobox
ProchlorperazineDrugBankDB00433 Y1.00infobox
ProchlorperazineECHA InfoCard100.000.3451.00infobox
ProchlorperazineElimination half-life4–8 hours, differs with the method of administration; 24 hours accounting for enterohepatic recirculation1.00infobox
ProchlorperazineExcretionBile duct, (colored) inactive metabolites in urine1.00infobox
ProchlorperazineFormulaC20H24ClN3S1.00infobox
ProchlorperazineIUPHAR/BPS72791.00infobox
ProchlorperazineKEGGD00493 Y1.00infobox
ProchlorperazineLegal statusAU: S4 (Prescription only) / S31.00infobox
ProchlorperazineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
ProchlorperazineLegal statusUK: POM (Prescription only) / P1.00infobox
ProchlorperazineLegal statusUS: ℞-only1.00infobox
ProchlorperazineLicense dataUS DailyMed: Prochlorperazine1.00infobox
ProchlorperazineMedlinePlusa6821161.00infobox
ProchlorperazineMetabolismMainly Liver (CYP2D6 and/or CYP3A4)1.00infobox
ProchlorperazineMolar mass373.94 g·mol−11.00infobox
ProchlorperazinePregnancy categoryAU: C1.00infobox
ProchlorperazineProtein binding91–99%1.00infobox
ProchlorperazinePubChem CID49171.00infobox
ProchlorperazineRoutes of administrationOral administration, rectal administration, intramuscular injection, intravenous injection (IV)1.00infobox
ProchlorperazineTrade namesCompazine, Stemetil, others1.00infobox

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