MED12

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Explore the main themes, entities and connections around MED12. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact Calcitriol receptor Cyclin-dependent kinase 8 Estrogen receptor alpha Gli3

10 related topics

Clinical significance

X-linked dominant Intellectual disability Lujan-Fryns syndrome FG syndrome Leiomyomas

7 related topics

Overview

Gene X chromosome

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: MED12, ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230, mediator complex subunit 12, Kto, HDKR
Band: Xq13.1 · X|X D
Bgee: right adrenal cortex · left ovary · right ovary · left adrenal gland · left adrenal cortex
BioGPS: More reference expression data
Chr.: X chromosome (human) · X chromosome (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes23

Edges22

Triples117

Avg. degree1.91

Density0.086957

Components1

How this topic connects Entity context

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MED12

Top relations

Gene ontology · 45

MED12 → androgen receptor signaling pathway, axis elongation involved in somitogenesis, beta-catenin binding, canonical Wnt signaling pathway, chromatin binding, development of the heart, embryonic brain development, embryonic neurocranium morphogenesis, embryonic organ development, endoderm development, intracellular steroid hormone receptor signaling pathway, mediator complex, membrane, negative regulation of Wnt signaling pathway, neural tube closure, neural tube development, nuclear receptor coactivator activity, nucleoplasm, nucleus, oligodendrocyte development

Bgee · 19

MED12 → adrenal gland, body of uterus, bone marrow, canal of the cervix, cerebellar cortex, genital tubercle, granulocyte, islet of Langerhans, left adrenal cortex, left adrenal gland, left ovary, neural layer of retina, right adrenal cortex, right lobe of thyroid gland, right ovary, right uterine tube, spleen, tail of embryo, thymus

RNA expression pattern · 19

related to Interactions · 7

MED12 → Calcitriol, Cyclin-dependent, G9a, Gli3, MED26, PPARGC1A, SOX9

related to Clinical significance · 5

MED12 → FG, Intellectual, Lujan-Fryns, Mutations, X-linked

Band · 2

MED12 → Xq13.1, X|X D

Chr. · 2

MED12 → X chromosome (human), X chromosome (mouse)

End · 2

MED12 → 100,341,071 bp, 71,144,103 bp

related to External links · 2

MED12 → GeneReviews/NCBI/NIH/UW, MED12-Related Disorders

Aliases · 1

MED12 → MED12, ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230, mediator complex subunit 12, Kto, HDKR

Important terminology Word statistics

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Important terminology

human bp chromosome chr band gene mediator 12 location mouse rna polymerase ii transcription subunit external complex 144 103 end

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
MED12	Aliases	MED12, ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230, mediator complex subunit 12, Kto, HDKR	1.00	infobox
MED12	Band	Xq13.1	1.00	infobox
MED12	Band	X\|X D	1.00	infobox
MED12	Bgee	right adrenal cortex	1.00	infobox
MED12	Bgee	left ovary	1.00	infobox
MED12	Bgee	right ovary	1.00	infobox
MED12	Bgee	left adrenal gland	1.00	infobox
MED12	Bgee	left adrenal cortex	1.00	infobox
MED12	Bgee	body of uterus	1.00	infobox
MED12	Bgee	right uterine tube	1.00	infobox
MED12	Bgee	spleen	1.00	infobox
MED12	Bgee	canal of the cervix	1.00	infobox
MED12	Bgee	right lobe of thyroid gland	1.00	infobox
MED12	Bgee	bone marrow	1.00	infobox
MED12	Bgee	tail of embryo	1.00	infobox
MED12	Bgee	islet of Langerhans	1.00	infobox
MED12	Bgee	genital tubercle	1.00	infobox
MED12	Bgee	neural layer of retina	1.00	infobox
MED12	Bgee	thymus	1.00	infobox
MED12	Bgee	adrenal gland	1.00	infobox
MED12	Bgee	cerebellar cortex	1.00	infobox
MED12	Bgee	granulocyte	1.00	infobox
MED12	BioGPS	More reference expression data	1.00	infobox
MED12	Chr.	X chromosome (human)	1.00	infobox
MED12	Chr.	X chromosome (mouse)	1.00	infobox
MED12	Databases	NCBI: entry; OMA: entry	1.00	infobox
MED12	End	71,144,103 bp	1.00	infobox
MED12	End	100,341,071 bp	1.00	infobox
MED12	Ensembl	ENSG00000184634	1.00	infobox
MED12	Entrez	9968	1.00	infobox

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