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Estrone

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History & Applications

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Overview

Biological activity

Biochemistry

Chemistry

Medical use

Contraindications

Side effects

History

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Map overview Semantic statistics

Estrone

Nodes142
Edges141
Triples88
Avg. degree1.99
Density0.014085
Components1

How this topic connects Entity context

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Estrone

Top relations

related to history · 25
Estrone → Adolf Butenandt, Allen, American, An, Anner, Butenandt, C17, DHEA, Doisy, Edgar Allen, Edward Doisy, Following, German, Hans Herloff Inhoffen, International Conference, It, London, Miescher, Nobel Prize, Russell Earl Marker
related to Biological activity · 13
Estrone → According, As, Because, Clinical, ERα, ERβ, Given, In, It, Oral, These, This, With
related to Chemistry · 9
Estrone → C1, C17, C18H22O2, C3, C5, CO, CO2, It, The
related to Biosynthesis · 6
Estrone → Action, HSD, In, Mechanism, The, This
related to Medical use · 4
Estrone → Additionally, Estrogens, HRT, This
related to Metabolism · 4
Estrone → Both, HSD, P450, The
related to Breast Cancer · 3
Estrone → Post-menopausal, The, Those
related to Contraindications · 3
Estrone → Estrogens, The, VTE
related to Distribution · 3
Estrone → As, It, SHBG
related to Excretion · 3
Estrone → Enterohepatic, Following, It

Important terminology Word statistics

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Important terminology

estradiol estrogens estrogen also estriol hormone use women levels breast precursor seen risk used cancer tissues menopausal activity 10 chemical

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
hot flashesinstance ofand relief of menopausal symptoms0.80text
estrone sulfateinstance ofestrone is relatively poorly bound to SHBG.MetabolismEstrone is conjugated into estrogen conjugates0.80text
estrone glucuronide by sulfotransferasesinstance ofestrone is relatively poorly bound to SHBG.MetabolismEstrone is conjugated into estrogen conjugates0.80text
glucuronidasesinstance ofestrone is relatively poorly bound to SHBG.MetabolismEstrone is conjugated into estrogen conjugates0.80text
and can also be hydroxylated by cytochrome P450 enzymes into catechol estrogens such as 2-hydroxyestroneinstance ofestrone is relatively poorly bound to SHBG.MetabolismEstrone is conjugated into estrogen conjugates0.80text
4-hydroxyestrone or into estriolinstance ofestrone is relatively poorly bound to SHBG.MetabolismEstrone is conjugated into estrogen conjugates0.80text
estrone sulfateinstance ofThe blood half-life of estrone is about 10 to 70 minutes and is similar to that of estradiol.ExcretionEstrone is excreted in urine in the form of estrogen conjugates0.80text
estrone sulfateinstance ofMetabolismEstrone is conjugated into estrogen conjugates0.80text
estrone glucuronide by sulfotransferasesinstance ofMetabolismEstrone is conjugated into estrogen conjugates0.80text
glucuronidasesinstance ofMetabolismEstrone is conjugated into estrogen conjugates0.80text
and can also be hydroxylated by cytochrome P450 enzymes into catechol estrogens such as 2-hydroxyestroneinstance ofMetabolismEstrone is conjugated into estrogen conjugates0.80text
4-hydroxyestrone or into estriolinstance ofMetabolismEstrone is conjugated into estrogen conjugates0.80text

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