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Insulin-like growth factor 1 (IGF1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. In the 1950s IGF1 was called "sulfation factor" because it stimulated sulfation of cartilage in vitro, and in the 1970s due to its effects it was…
The analysis highlights Applications and Art as prominent areas in the source structure around Insulin-like growth factor 1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Insulin-like growth factor 1 shows recurring relationship patterns in the source. For example, Insulin-like growth factor 1 → activation of protein kinase B activity, alphav-beta3 integrin-IGF-1-IGF1R complex, bone mineralization involved in bone maturation, cell activation, cell population proliferation, cellular response to amyloid-beta, DNA replication, ERK1 and ERK2 cascade, exocytic vesicle, extracellular region, extracellular space, glycolate metabolic process, growth factor activity, hormone activity, insulin receptor binding, insulin-like growth factor binding protein complex, insulin-like growth factor receptor binding, insulin-like growth factor receptor signaling pathway, insulin-like growth factor ternary complex, integrin binding Another extracted example is Insulin-like growth factor 1 → caput epididymis, corpus epididymis, efferent ductule, endometrium, external carotid artery, gallbladder, gastric mucosa, genital tubercle, internal carotid artery, iris, left lobe of liver, pericardium, seminal vesicula, stria vascularis, stroma of bone marrow, superficial temporal artery, tail of epididymis, tendon of biceps brachii, urethra, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
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TTTA extracted 161 structured relationships around Insulin-like growth factor 1. Examples in this analysis include Insulin-like growth factor 1 → Aliases → IGF1, IGF-I, IGF1A, IGFI, MGF, insulin like growth factor 1, IGF and Insulin-like growth factor 1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1B9G, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSR, 2GF1, 3GF1, 3LRI, 1BQT, 4XSS. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Insulin-like growth factor 1 | Aliases | IGF1, IGF-I, IGF1A, IGFI, MGF, insulin like growth factor 1, IGF | 1.00 | infobox |
| Insulin-like growth factor 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1B9G, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSR, 2GF1, 3GF1, 3LRI, 1BQT, 4XSS | 1.00 | infobox |
| Insulin-like growth factor 1 | Band | 12q23.2 | 1.00 | infobox |
| Insulin-like growth factor 1 | Band | 10 C1|10 43.7 cM | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | pericardium | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | tail of epididymis | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | gastric mucosa | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | superficial temporal artery | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | seminal vesicula | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | urethra | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | caput epididymis | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | corpus epididymis | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | endometrium | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | stria vascularis | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | internal carotid artery | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | efferent ductule | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | external carotid artery | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | iris | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | left lobe of liver | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | gallbladder | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | genital tubercle | 1.00 | infobox |
| Insulin-like growth factor 1 | Bgee | white adipose tissue | 1.00 | infobox |
| Insulin-like growth factor 1 | BioGPS | More reference expression data | 1.00 | infobox |
| Insulin-like growth factor 1 | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| Insulin-like growth factor 1 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| Insulin-like growth factor 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Insulin-like growth factor 1 | End | 102,481,744 bp | 1.00 | infobox |
| Insulin-like growth factor 1 | End | 87,772,904 bp | 1.00 | infobox |
The concept neighborhoods around Insulin-like growth factor 1 bring nearby vocabulary together. In this analysis, examples include Hormone, Factor and Growth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Insulin-like growth factor 1, one of the stronger structural bridges in this analysis connects Insulin-like growth factor 1 with Mechanism of action. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Insulin-like growth factor 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Insulin-like growth factor 1 · EN edition · Analysis: TopicsToTalkAbout