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The nuclear receptor coactivator 1 (NCOA1), also called steroid receptor coactivator-1 (SRC-1), is a transcriptional coregulatory protein that contains several nuclear receptor–interacting domains and possesses intrinsic histone acetyltransferase activity. It is encoded by the gene NCOA1.
The analysis highlights Interactions and Overview as prominent areas in the source structure around Nuclear receptor coactivator 1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around Nuclear receptor coactivator 1 shows recurring relationship patterns in the source. For example, Nuclear receptor coactivator 1 → acyltransferase activity, androgen receptor binding, androgen receptor signaling pathway, aryl hydrocarbon receptor binding, bile acid and bile salt transport, cellular response to hormone stimulus, cellular response to Thyroglobulin triiodothyronine, cerebellum development, cerebral cortex development, chromatin binding, cytoplasm, cytosol, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, enzyme binding, estrogen receptor binding, estrous cycle, hippocampus development, histone acetyltransferase activity, histone H4 acetylation Another extracted example is Nuclear receptor coactivator 1 → anterior amygdaloid area, Brodmann area 23, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, frontal pole, lateral geniculate nucleus, lateral septal nucleus, mammillary body, middle frontal gyrus, middle temporal gyrus, motor neuron, paraflocculus of cerebellum, postcentral gyrus, Region I of hippocampus proper, retinal pigment epithelium, Rostral migratory stream, subiculum, tibialis anterior muscle, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
ncoa1 nuclear coactivator bp chr dna human band receptor gene chromosome activity protein location receptors promoter mouse histone acetyltransferase transcription
TTTA extracted 136 structured relationships around Nuclear receptor coactivator 1. Examples in this analysis include Nuclear receptor coactivator 1 → 2.3.1.48 → ↗ and Nuclear receptor coactivator 1 → Aliases → NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Nuclear receptor coactivator 1 | 2.3.1.48 | ↗ | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Aliases | NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1 | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9,… | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Band | 2p23.3 | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Band | 12|12 A1.1 | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | middle temporal gyrus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | middle frontal gyrus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | paraflocculus of cerebellum | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | Brodmann area 23 | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | entorhinal cortex | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | postcentral gyrus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | frontal pole | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | endothelial cell | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | Rostral migratory stream | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | retinal pigment epithelium | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | lateral septal nucleus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | lateral geniculate nucleus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | anterior amygdaloid area | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | motor neuron | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | ventromedial nucleus | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | mammillary body | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Bgee | subiculum | 1.00 | infobox |
| Nuclear receptor coactivator 1 | BioGPS | More reference expression data | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| Nuclear receptor coactivator 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Nuclear receptor coactivator 1 | End | 24,770,702 bp | 1.00 | infobox |
The concept neighborhoods around Nuclear receptor coactivator 1 bring nearby vocabulary together. In this analysis, examples include Coactivator, Nuclear and Ncoa1. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Nuclear receptor coactivator 1, one of the stronger structural bridges in this analysis connects Nuclear receptor coactivator 1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Nuclear receptor coactivator 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Nuclear receptor coactivator 1 · EN edition · Analysis: TopicsToTalkAbout