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Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene.
The analysis highlights Function, Role in cardiac development and Interactions as prominent areas in the source structure around ISL1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around ISL1 shows recurring relationship patterns in the source. For example, ISL1 → atrial septum morphogenesis, axon regeneration, axonogenesis, bHLH transcription factor binding, cardiac cell fate determination, cardiac muscle cell myoblast differentiation, cardiac right ventricle morphogenesis, cell differentiation, cellular response to glucocorticoid stimulus, chromatin binding, cis-regulatory region sequence-specific DNA binding, cytoplasm, development of the heart, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, endocardial cushion morphogenesis, estrogen receptor binding, heart morphogenesis, innervation Another extracted example is ISL1 → buccal mucosa cell, cardia, facial motor nucleus, gastric mucosa, genital tubercle, human penis, islet of Langerhans, lumbar spinal ganglion, medial ganglionic eminence, median eminence, neural layer of retina, pancreatic ductal cell, pylorus, secondary oocyte, sperm, superior cervical ganglion, trigeminal ganglion, urethra, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cardiac bp gene human chr band chromosome protein cell heart mouse neural location function cells differentiation field crest insulin isl-1
TTTA extracted 159 structured relationships around ISL1. Examples in this analysis include ISL1 → Aliases → ISL1, ISLET1, Isl-1, ISL LIM homeobox 1 and ISL1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RGT, 4JCJ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ISL1 | Aliases | ISL1, ISLET1, Isl-1, ISL LIM homeobox 1 | 1.00 | infobox |
| ISL1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RGT, 4JCJ | 1.00 | infobox |
| ISL1 | Band | 5q11.1 | 1.00 | infobox |
| ISL1 | Band | 13|13 D2.2 | 1.00 | infobox |
| ISL1 | Bgee | secondary oocyte | 1.00 | infobox |
| ISL1 | Bgee | islet of Langerhans | 1.00 | infobox |
| ISL1 | Bgee | human penis | 1.00 | infobox |
| ISL1 | Bgee | urethra | 1.00 | infobox |
| ISL1 | Bgee | pylorus | 1.00 | infobox |
| ISL1 | Bgee | cardia | 1.00 | infobox |
| ISL1 | Bgee | sperm | 1.00 | infobox |
| ISL1 | Bgee | buccal mucosa cell | 1.00 | infobox |
| ISL1 | Bgee | pancreatic ductal cell | 1.00 | infobox |
| ISL1 | Bgee | gastric mucosa | 1.00 | infobox |
| ISL1 | Bgee | superior cervical ganglion | 1.00 | infobox |
| ISL1 | Bgee | genital tubercle | 1.00 | infobox |
| ISL1 | Bgee | trigeminal ganglion | 1.00 | infobox |
| ISL1 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| ISL1 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| ISL1 | Bgee | neural layer of retina | 1.00 | infobox |
| ISL1 | Bgee | facial motor nucleus | 1.00 | infobox |
| ISL1 | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| ISL1 | Bgee | median eminence | 1.00 | infobox |
| ISL1 | BioGPS | More reference expression data | 1.00 | infobox |
| ISL1 | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| ISL1 | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| ISL1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ISL1 | End | 51,394,730 bp | 1.00 | infobox |
| ISL1 | End | 116,446,225 bp | 1.00 | infobox |
| ISL1 | Ensembl | ENSG00000016082 | 1.00 | infobox |
The concept neighborhoods around ISL1 bring nearby vocabulary together. In this analysis, examples include Cardiac, Crest and Field. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For ISL1, one of the stronger structural bridges in this analysis connects ISL1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around ISL1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Role in cardiac development & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — ISL1 · EN edition · Analysis: TopicsToTalkAbout