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SHC-transforming protein 1 is a protein that in humans is encoded by the SHC1 gene. SHC has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells.
The analysis highlights Gene and expression, Function and Overview as prominent areas in the source structure around SHC1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SHC1 shows recurring relationship patterns in the source. For example, SHC1 → actin cytoskeleton reorganization, angiogenesis, axon guidance, cell-cell adhesion, cellular response to growth factor stimulus, cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response to bacterium, development of the heart, ephrin receptor binding, epidermal growth factor binding, epidermal growth factor receptor binding, epidermal growth factor receptor signaling pathway, ERBB2 signaling pathway, Fc-epsilon receptor signaling pathway, insulin receptor binding, insulin receptor signaling pathway, insulin-like growth factor receptor binding, interleukin-15-mediated signaling pathway Another extracted example is SHC1 → anterior pituitary, canal of the cervix, cartilage tissue, Descending thoracic aorta, epiblast, gallbladder, gastric mucosa, genital tubercle, granulocyte, islet of Langerhans, left uterine tube, lens, lung, right lobe of thyroid gland, smooth muscle tissue, stomach, stromal cell of endometrium, tail of embryo, uterus, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
p66shc shc proteins gene protein stress oxidative cell bp signaling pathway mct-1 chr human band expression cells chromosome regulation also
TTTA extracted 160 structured relationships around SHC1. Examples in this analysis include SHC1 → Aliases → SHC1, SHC, SHCA, SHC adaptor protein 1 and SHC1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MIL, 1N3H, 1OY2, 1QG1, 1SHC, 1TCE, 2L1C, 4JMH, 4XWX, 5CZI. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SHC1 | Aliases | SHC1, SHC, SHCA, SHC adaptor protein 1 | 1.00 | infobox |
| SHC1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MIL, 1N3H, 1OY2, 1QG1, 1SHC, 1TCE, 2L1C, 4JMH, 4XWX, 5CZI | 1.00 | infobox |
| SHC1 | Band | 1q21.3 | 1.00 | infobox |
| SHC1 | Band | 3 F1|3 39.11 cM | 1.00 | infobox |
| SHC1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| SHC1 | Bgee | gallbladder | 1.00 | infobox |
| SHC1 | Bgee | smooth muscle tissue | 1.00 | infobox |
| SHC1 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| SHC1 | Bgee | gastric mucosa | 1.00 | infobox |
| SHC1 | Bgee | anterior pituitary | 1.00 | infobox |
| SHC1 | Bgee | left uterine tube | 1.00 | infobox |
| SHC1 | Bgee | cartilage tissue | 1.00 | infobox |
| SHC1 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| SHC1 | Bgee | canal of the cervix | 1.00 | infobox |
| SHC1 | Bgee | lens | 1.00 | infobox |
| SHC1 | Bgee | tail of embryo | 1.00 | infobox |
| SHC1 | Bgee | granulocyte | 1.00 | infobox |
| SHC1 | Bgee | uterus | 1.00 | infobox |
| SHC1 | Bgee | genital tubercle | 1.00 | infobox |
| SHC1 | Bgee | lung | 1.00 | infobox |
| SHC1 | Bgee | yolk sac | 1.00 | infobox |
| SHC1 | Bgee | islet of Langerhans | 1.00 | infobox |
| SHC1 | Bgee | epiblast | 1.00 | infobox |
| SHC1 | Bgee | stomach | 1.00 | infobox |
| SHC1 | BioGPS | More reference expression data | 1.00 | infobox |
| SHC1 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| SHC1 | Chr. | Chromosome 3 (mouse) | 1.00 | infobox |
| SHC1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SHC1 | End | 154,974,395 bp | 1.00 | infobox |
| SHC1 | End | 89,337,334 bp | 1.00 | infobox |
The concept neighborhoods around SHC1 bring nearby vocabulary together. In this analysis, examples include Proteins, Cell and Signaling. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SHC1, one of the stronger structural bridges in this analysis connects SHC1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SHC1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Gene and expression, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SHC1 · EN edition · Analysis: TopicsToTalkAbout