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Mediator of RNA polymerase II transcription subunit 1 also known as DRIP205 or Trap220 is a subunit of the Mediator complex and is a protein that in humans is encoded by the MED1 gene. MED1 functions as a nuclear receptor coactivator.
The analysis highlights Measurement, Function and Interactions as prominent areas in the source structure around MED1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MED1 shows recurring relationship patterns in the source. For example, MED1 → androgen biosynthetic process, androgen receptor signaling pathway, angiogenesis, animal organ morphogenesis, animal organ regeneration, brain development, camera-type eye development, cell morphogenesis, cellular response to epidermal growth factor stimulus, cellular response to hepatocyte growth factor stimulus, cellular response to steroid hormone stimulus, cellular response to thyroid hormone stimulus, chromatin, chromatin binding, chromatin DNA binding, development of the heart, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic heart tube development, embryonic hemopoiesis Another extracted example is MED1 → buccal mucosa cell, cumulus cell, genital tubercle, hair follicle, human penis, internal carotid artery, lower lobe of lung, mucosa of paranasal sinus, nipple, otic placode, parietal pleura, Rostral migratory stream, spermatid, spermatocyte, superficial temporal artery, tail of embryo, tendon of biceps brachii, trabecular bone, vestibular membrane of cochlear duct, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp protein complex gene chr human band mediator chromosome 17 rna polymerase ii transcription subunit nuclear receptor location function dna
TTTA extracted 176 structured relationships around MED1. Examples in this analysis include MED1 → Aliases → MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, mediator complex subunit 1 and MED1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RJK, 1RK3, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 3A2H, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3W0G, 3W0H, 3W0I,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MED1 | Aliases | MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, mediator complex subunit 1 | 1.00 | infobox |
| MED1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RJK, 1RK3, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 3A2H, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3W0G, 3W0H, 3W0I,… | 1.00 | infobox |
| MED1 | Band | 17q12 | 1.00 | infobox |
| MED1 | Band | 11 D|11 61.75 cM | 1.00 | infobox |
| MED1 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| MED1 | Bgee | nipple | 1.00 | infobox |
| MED1 | Bgee | visceral pleura | 1.00 | infobox |
| MED1 | Bgee | lower lobe of lung | 1.00 | infobox |
| MED1 | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| MED1 | Bgee | superficial temporal artery | 1.00 | infobox |
| MED1 | Bgee | parietal pleura | 1.00 | infobox |
| MED1 | Bgee | trabecular bone | 1.00 | infobox |
| MED1 | Bgee | human penis | 1.00 | infobox |
| MED1 | Bgee | buccal mucosa cell | 1.00 | infobox |
| MED1 | Bgee | Rostral migratory stream | 1.00 | infobox |
| MED1 | Bgee | cumulus cell | 1.00 | infobox |
| MED1 | Bgee | spermatocyte | 1.00 | infobox |
| MED1 | Bgee | spermatid | 1.00 | infobox |
| MED1 | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| MED1 | Bgee | hair follicle | 1.00 | infobox |
| MED1 | Bgee | tail of embryo | 1.00 | infobox |
| MED1 | Bgee | otic placode | 1.00 | infobox |
| MED1 | Bgee | internal carotid artery | 1.00 | infobox |
| MED1 | Bgee | genital tubercle | 1.00 | infobox |
| MED1 | BioGPS | More reference expression data | 1.00 | infobox |
| MED1 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| MED1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| MED1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MED1 | End | 39,451,272 bp | 1.00 | infobox |
| MED1 | End | 98,084,119 bp | 1.00 | infobox |
The concept neighborhoods around MED1 bring nearby vocabulary together. In this analysis, examples include Mediator, Nuclear and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MED1, one of the stronger structural bridges in this analysis connects MED1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MED1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MED1 · EN edition · Analysis: TopicsToTalkAbout