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MED1

Mediator of RNA polymerase II transcription subunit 1 also known as DRIP205 or Trap220 is a subunit of the Mediator complex and is a protein that in humans is encoded by the MED1 gene. MED1 functions as a nuclear receptor coactivator.

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Aliases
MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, mediator complex subunit 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RJK, 1RK3, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 3A2H, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3W0G, 3W0H, 3W0I,…
Band
17q12 · 11 D|11 61.75 cM
Bgee
tendon of biceps brachii · nipple · visceral pleura · lower lobe of lung · mucosa of paranasal sinus
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Function

Interactions

Protein family

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Map overview Semantic statistics

MED1

Nodes31
Edges30
Triples176
Avg. degree1.94
Density0.064516
Components1

How this topic connects Entity context

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MED1

Top relations

Gene ontology · 98
MED1 → androgen biosynthetic process, androgen receptor signaling pathway, angiogenesis, animal organ morphogenesis, animal organ regeneration, brain development, camera-type eye development, cell morphogenesis, cellular response to epidermal growth factor stimulus, cellular response to hepatocyte growth factor stimulus, cellular response to steroid hormone stimulus, cellular response to thyroid hormone stimulus, chromatin, chromatin binding, chromatin DNA binding, development of the heart, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic heart tube development, embryonic hemopoiesis
Bgee · 20
MED1 → buccal mucosa cell, cumulus cell, genital tubercle, hair follicle, human penis, internal carotid artery, lower lobe of lung, mucosa of paranasal sinus, nipple, otic placode, parietal pleura, Rostral migratory stream, spermatid, spermatocyte, superficial temporal artery, tail of embryo, tendon of biceps brachii, trabecular bone, vestibular membrane of cochlear duct, visceral pleura
RNA expression pattern · 20
MED1 → buccal mucosa cell, cumulus cell, genital tubercle, hair follicle, human penis, internal carotid artery, lower lobe of lung, mucosa of paranasal sinus, nipple, otic placode, parietal pleura, Rostral migratory stream, spermatid, spermatocyte, superficial temporal artery, tail of embryo, tendon of biceps brachii, trabecular bone, vestibular membrane of cochlear duct, visceral pleura
related to Interactions · 9
MED1 → Androgen, Calcitriol, Cyclin-dependent, Estrogen, Glucocorticoid, Hepatocyte, P53, PPARGC1A, TGS1
related to Protein family · 6
MED1 → It, Med9, Mediator, Srb/Med, The Med1, This
Band · 2
MED1 → 11 D|11 61.75 cM, 17q12
Chr. · 2
MED1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
MED1 → 39,451,272 bp, 98,084,119 bp
Aliases · 1
MED1 → MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, mediator complex subunit 1
Available structures · 1
MED1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RJK, 1RK3, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 3A2H, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3W0G, 3W0H, 3W0I,…

Important terminology Word statistics

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Important terminology

bp protein complex gene chr human band mediator chromosome 17 rna polymerase ii transcription subunit nuclear receptor location function dna

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MED1AliasesMED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, mediator complex subunit 11.00infobox
MED1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RJK, 1RK3, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 3A2H, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3W0G, 3W0H, 3W0I,…1.00infobox
MED1Band17q121.00infobox
MED1Band11 D|11 61.75 cM1.00infobox
MED1Bgeetendon of biceps brachii1.00infobox
MED1Bgeenipple1.00infobox
MED1Bgeevisceral pleura1.00infobox
MED1Bgeelower lobe of lung1.00infobox
MED1Bgeemucosa of paranasal sinus1.00infobox
MED1Bgeesuperficial temporal artery1.00infobox
MED1Bgeeparietal pleura1.00infobox
MED1Bgeetrabecular bone1.00infobox
MED1Bgeehuman penis1.00infobox
MED1Bgeebuccal mucosa cell1.00infobox
MED1BgeeRostral migratory stream1.00infobox
MED1Bgeecumulus cell1.00infobox
MED1Bgeespermatocyte1.00infobox
MED1Bgeespermatid1.00infobox
MED1Bgeevestibular membrane of cochlear duct1.00infobox
MED1Bgeehair follicle1.00infobox
MED1Bgeetail of embryo1.00infobox
MED1Bgeeotic placode1.00infobox
MED1Bgeeinternal carotid artery1.00infobox
MED1Bgeegenital tubercle1.00infobox
MED1BioGPSMore reference expression data1.00infobox
MED1Chr.Chromosome 17 (human)1.00infobox
MED1Chr.Chromosome 11 (mouse)1.00infobox
MED1DatabasesNCBI: entry; OMA: entry1.00infobox
MED1End39,451,272 bp1.00infobox
MED1End98,084,119 bp1.00infobox

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