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Phospholipase C, gamma 1, also known as PLCG1 and PLCgamma1, is a protein that in humans involved in cell growth, migration, apoptosis, and proliferation. It is encoded by the PLCG1 gene and is part of the PLC superfamily.
The analysis highlights Art, Function and Interactions as prominent areas in the source structure around PLCG1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PLCG1 shows recurring relationship patterns in the source. For example, PLCG1 → activation of phospholipase C activity, axon guidance, calcium ion binding, calcium ion transport, calcium-mediated signaling, cell migration, cell projection, cell-cell junction, cellular response to epidermal growth factor stimulus, COP9 signalosome, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, Fc-epsilon receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, glutamate receptor binding, glutamatergic synapse, hydrolase activity, in utero embryonic development, inositol phosphate metabolic process Another extracted example is PLCG1 → Aldrich, BAG3, Cbl, CD117, CD31, Eukaryotic, FLT1, GAB1, GIT1, Grb2, HER2/neu, IRS2, ITK, KHDRBS1, Linker, Lymphocyte, PDGFRA, PLD2, RHOA, SOS1. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
plcγ1 growth cell cells protein gene bp also tyrosine chr human band proliferation cancer receptor factor involved cish phospholipase chromosome
TTTA extracted 164 structured relationships around PLCG1. Examples in this analysis include PLCG1 → 3.1.4.11 → ↗ and PLCG1 → Aliases → PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1, phospholipase C gamma 1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PLCG1 | 3.1.4.11 | ↗ | 1.00 | infobox |
| PLCG1 | Aliases | PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1, phospholipase C gamma 1 | 1.00 | infobox |
| PLCG1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HSQ, 2HSP, 4EY0, 4FBN | 1.00 | infobox |
| PLCG1 | Band | 20q12 | 1.00 | infobox |
| PLCG1 | Band | 2 H2|2 80.97 cM | 1.00 | infobox |
| PLCG1 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| PLCG1 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| PLCG1 | Bgee | ganglionic eminence | 1.00 | infobox |
| PLCG1 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| PLCG1 | Bgee | right ovary | 1.00 | infobox |
| PLCG1 | Bgee | ventricular zone | 1.00 | infobox |
| PLCG1 | Bgee | canal of the cervix | 1.00 | infobox |
| PLCG1 | Bgee | body of uterus | 1.00 | infobox |
| PLCG1 | Bgee | left ovary | 1.00 | infobox |
| PLCG1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| PLCG1 | Bgee | otolith organ | 1.00 | infobox |
| PLCG1 | Bgee | hand | 1.00 | infobox |
| PLCG1 | Bgee | utricle | 1.00 | infobox |
| PLCG1 | Bgee | aortic valve | 1.00 | infobox |
| PLCG1 | Bgee | ascending aorta | 1.00 | infobox |
| PLCG1 | Bgee | Rostral migratory stream | 1.00 | infobox |
| PLCG1 | Bgee | fossa | 1.00 | infobox |
| PLCG1 | Bgee | cumulus cell | 1.00 | infobox |
| PLCG1 | Bgee | internal carotid artery | 1.00 | infobox |
| PLCG1 | Bgee | condyle | 1.00 | infobox |
| PLCG1 | BioGPS | More reference expression data | 1.00 | infobox |
| PLCG1 | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| PLCG1 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| PLCG1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PLCG1 | End | 41,196,801 bp | 1.00 | infobox |
The concept neighborhoods around PLCG1 bring nearby vocabulary together. In this analysis, examples include Receptor, Activated and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PLCG1, one of the stronger structural bridges in this analysis connects PLCG1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PLCG1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PLCG1 · EN edition · Analysis: TopicsToTalkAbout