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CD31

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3. PECAM-1 plays a key role in removing aged neutrophils from the body.

Role of CD31 in diseases, Function & Tissue distribution

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Aliases
PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KY5, 5C14
Band
17q23.3 · 11|11 E1
Bgee
tendon of biceps brachii · visceral pleura · lower lobe of lung · pericardium · right lung
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Structure

Tissue distribution

Function

Role of CD31 in diseases

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Map overview Semantic statistics

CD31

Nodes54
Edges53
Triples130
Avg. degree1.96
Density0.037037
Components1

How this topic connects Entity context

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CD31

Top relations

Gene ontology · 39
CD31 → angiogenesis, cell adhesion, cell junction, cell periphery, cell recognition, cell-cell adhesion via plasma-membrane adhesion molecules, cell-cell contact zone, cytoplasm, diapedesis, endothelial cell migration, endothelial cell morphogenesis, endothelial cell-matrix adhesion, external side of plasma membrane, extracellular exosome, extracellular matrix organization, extracellular space, glomerular endothelium development, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, leukocyte cell-cell adhesion
Bgee · 20
CD31 → aortic valve, ascending aorta, digastric muscle, epithelium of colon, glomerular capillary, left lung, left lung lobe, lower lobe of lung, mesenteric lymph nodes, monocyte, muscle of thigh, parietal pleura, pericardium, right lung, right lung lobe, tendon of biceps brachii, upper lobe of left lung, upper lobe of lung, vasculature of trunk, visceral pleura
RNA expression pattern · 20
CD31 → aortic valve, ascending aorta, digastric muscle, epithelium of colon, glomerular capillary, left lung, left lung lobe, lower lobe of lung, mesenteric lymph nodes, monocyte, muscle of thigh, parietal pleura, pericardium, right lung, right lung lobe, tendon of biceps brachii, upper lobe of left lung, upper lobe of lung, vasculature of trunk, visceral pleura
related to Function · 4
CD31 → CD38, PECAM-1, T-cells, The
related to Immunohistochemistry · 4
CD31 → In, It, Malignant, This
Band · 2
CD31 → 11|11 E1, 17q23.3
Chr. · 2
CD31 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
CD31 → 106,641,454 bp, 64,413,776 bp
related to Tissue distribution · 2
CD31 → Kupffer, NK
Aliases · 1
CD31 → PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1

Important terminology Word statistics

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Important terminology

pecam-1 endothelial cell protein adhesion bp gene leukocyte human interactions chr angiogenesis band pecam1 neutrophils domain high cells found platelet

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD31AliasesPECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-11.00infobox
CD31Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KY5, 5C141.00infobox
CD31Band17q23.31.00infobox
CD31Band11|11 E11.00infobox
CD31Bgeetendon of biceps brachii1.00infobox
CD31Bgeevisceral pleura1.00infobox
CD31Bgeelower lobe of lung1.00infobox
CD31Bgeepericardium1.00infobox
CD31Bgeeright lung1.00infobox
CD31Bgeeparietal pleura1.00infobox
CD31Bgeemonocyte1.00infobox
CD31Bgeeupper lobe of lung1.00infobox
CD31Bgeeepithelium of colon1.00infobox
CD31Bgeeupper lobe of left lung1.00infobox
CD31Bgeeright lung lobe1.00infobox
CD31Bgeeleft lung1.00infobox
CD31Bgeeleft lung lobe1.00infobox
CD31Bgeevasculature of trunk1.00infobox
CD31Bgeemesenteric lymph nodes1.00infobox
CD31Bgeemuscle of thigh1.00infobox
CD31Bgeeascending aorta1.00infobox
CD31Bgeeaortic valve1.00infobox
CD31Bgeeglomerular capillary1.00infobox
CD31Bgeedigastric muscle1.00infobox
CD31BioGPSMore reference expression data1.00infobox
CD31Chr.Chromosome 17 (human)1.00infobox
CD31Chr.Chromosome 11 (mouse)1.00infobox
CD31DatabasesNCBI: entry; OMA: entry1.00infobox
CD31End64,413,776 bp1.00infobox
CD31End106,641,454 bp1.00infobox

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