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Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3. PECAM-1 plays a key role in removing aged neutrophils from the body.
The analysis highlights Role of CD31 in diseases, Function and Tissue distribution as prominent areas in the source structure around CD31.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CD31 shows recurring relationship patterns in the source. For example, CD31 → angiogenesis, cell adhesion, cell junction, cell periphery, cell recognition, cell-cell adhesion via plasma-membrane adhesion molecules, cell-cell contact zone, cytoplasm, diapedesis, endothelial cell migration, endothelial cell morphogenesis, endothelial cell-matrix adhesion, external side of plasma membrane, extracellular exosome, extracellular matrix organization, extracellular space, glomerular endothelium development, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, leukocyte cell-cell adhesion Another extracted example is CD31 → aortic valve, ascending aorta, digastric muscle, epithelium of colon, glomerular capillary, left lung, left lung lobe, lower lobe of lung, mesenteric lymph nodes, monocyte, muscle of thigh, parietal pleura, pericardium, right lung, right lung lobe, tendon of biceps brachii, upper lobe of left lung, upper lobe of lung, vasculature of trunk, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
pecam-1 endothelial cell protein adhesion bp gene leukocyte human interactions chr angiogenesis band pecam1 neutrophils domain high cells found platelet
TTTA extracted 130 structured relationships around CD31. Examples in this analysis include CD31 → Aliases → PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1 and CD31 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KY5, 5C14. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD31 | Aliases | PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1 | 1.00 | infobox |
| CD31 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KY5, 5C14 | 1.00 | infobox |
| CD31 | Band | 17q23.3 | 1.00 | infobox |
| CD31 | Band | 11|11 E1 | 1.00 | infobox |
| CD31 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| CD31 | Bgee | visceral pleura | 1.00 | infobox |
| CD31 | Bgee | lower lobe of lung | 1.00 | infobox |
| CD31 | Bgee | pericardium | 1.00 | infobox |
| CD31 | Bgee | right lung | 1.00 | infobox |
| CD31 | Bgee | parietal pleura | 1.00 | infobox |
| CD31 | Bgee | monocyte | 1.00 | infobox |
| CD31 | Bgee | upper lobe of lung | 1.00 | infobox |
| CD31 | Bgee | epithelium of colon | 1.00 | infobox |
| CD31 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CD31 | Bgee | right lung lobe | 1.00 | infobox |
| CD31 | Bgee | left lung | 1.00 | infobox |
| CD31 | Bgee | left lung lobe | 1.00 | infobox |
| CD31 | Bgee | vasculature of trunk | 1.00 | infobox |
| CD31 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CD31 | Bgee | muscle of thigh | 1.00 | infobox |
| CD31 | Bgee | ascending aorta | 1.00 | infobox |
| CD31 | Bgee | aortic valve | 1.00 | infobox |
| CD31 | Bgee | glomerular capillary | 1.00 | infobox |
| CD31 | Bgee | digastric muscle | 1.00 | infobox |
| CD31 | BioGPS | More reference expression data | 1.00 | infobox |
| CD31 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| CD31 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| CD31 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD31 | End | 64,413,776 bp | 1.00 | infobox |
| CD31 | End | 106,641,454 bp | 1.00 | infobox |
The concept neighborhoods around CD31 bring nearby vocabulary together. In this analysis, examples include Cells, Immunohistochemistry and Endothelial. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CD31, one of the stronger structural bridges in this analysis connects CD31 with Role of CD31 in diseases. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CD31 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role of CD31 in diseases, Function & Tissue distribution, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CD31 · EN edition · Analysis: TopicsToTalkAbout