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KHDRBS1: Research, Clinical significance & Gene knockout studies

KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene.

Language: English [EN]
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KHDRBS1 topic overview

The analysis highlights Research, Clinical significance and Gene knockout studies as prominent areas in the source structure around KHDRBS1.

Related topics
36
Source areas
4
Connected nodes
40
Extracted relationships
104
Concept neighborhoods
21
Bridge connections
40

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 20 topics
Overview · 7 topics
Gene knockout studies · 6 topics
Function · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
KHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2XA6, 3QHE
Band
1p35.2 · 4|4 D2.2
Bgee
germinal epithelium · ganglionic eminence · parietal pleura · tendon of biceps brachii · visceral pleura
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Gene knockout studies

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How KHDRBS1 connects Entity context

The extracted context around KHDRBS1 shows recurring relationship patterns in the source. For example, KHDRBS1 → cell cycle, cell population proliferation, cell surface receptor signaling pathway, cytoplasm, cytosol, DNA binding, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, Grb2-Sos complex, identical protein binding, membrane, mRNA processing, negative regulation of transcription, DNA-templated, nucleic acid binding, nucleoplasm, nucleus, poly(A) binding, poly(U) RNA binding, positive regulation of RNA export from nucleus, positive regulation of signal transduction Another extracted example is KHDRBS1 → abdominal wall, atrium, ganglionic eminence, germinal epithelium, gingival epithelium, human fetus, lower lobe of lung, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, parietal pleura, primitive streak, somite, superficial temporal artery, tendon of biceps brachii, ventricular zone, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

KHDRBS1

Top relations

Gene ontology · 35
KHDRBS1 → cell cycle, cell population proliferation, cell surface receptor signaling pathway, cytoplasm, cytosol, DNA binding, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, Grb2-Sos complex, identical protein binding, membrane, mRNA processing, negative regulation of transcription, DNA-templated, nucleic acid binding, nucleoplasm, nucleus, poly(A) binding, poly(U) RNA binding, positive regulation of RNA export from nucleus, positive regulation of signal transduction
Bgee · 18
KHDRBS1 → abdominal wall, atrium, ganglionic eminence, germinal epithelium, gingival epithelium, human fetus, lower lobe of lung, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, parietal pleura, primitive streak, somite, superficial temporal artery, tendon of biceps brachii, ventricular zone, visceral pleura
RNA expression pattern · 18
KHDRBS1 → abdominal wall, atrium, ganglionic eminence, germinal epithelium, gingival epithelium, human fetus, lower lobe of lung, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, parietal pleura, primitive streak, somite, superficial temporal artery, tendon of biceps brachii, ventricular zone, visceral pleura
related to Function · 8
KHDRBS1 → AA, KH, KH-type RNA, Mitosis, RNA, Sam68, Src-Associated, U/A
Band · 2
KHDRBS1 → 1p35.2, 4|4 D2.2
Chr. · 2
KHDRBS1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
KHDRBS1 → 129,636,096 bp, 32,060,850 bp
Aliases · 1
KHDRBS1 → KHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 1
Available structures · 1
KHDRBS1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2XA6, 3QHE
BioGPS · 1
KHDRBS1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

sam68 alternative splicing gene protein mice human rna signal bp cancer sam68- chr band cell expression shown domain binding chromosome

KHDRBS1 relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around KHDRBS1. Examples in this analysis include KHDRBS1 → Aliases → KHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 1 and KHDRBS1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2XA6, 3QHE. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
KHDRBS1AliasesKHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 11.00infobox
KHDRBS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2XA6, 3QHE1.00infobox
KHDRBS1Band1p35.21.00infobox
KHDRBS1Band4|4 D2.21.00infobox
KHDRBS1Bgeegerminal epithelium1.00infobox
KHDRBS1Bgeeganglionic eminence1.00infobox
KHDRBS1Bgeeparietal pleura1.00infobox
KHDRBS1Bgeetendon of biceps brachii1.00infobox
KHDRBS1Bgeevisceral pleura1.00infobox
KHDRBS1Bgeeventricular zone1.00infobox
KHDRBS1Bgeesuperficial temporal artery1.00infobox
KHDRBS1Bgeemucosa of paranasal sinus1.00infobox
KHDRBS1Bgeegingival epithelium1.00infobox
KHDRBS1Bgeelower lobe of lung1.00infobox
KHDRBS1Bgeemandibular prominence1.00infobox
KHDRBS1Bgeemaxillary prominence1.00infobox
KHDRBS1Bgeemedial ganglionic eminence1.00infobox
KHDRBS1Bgeesomite1.00infobox
KHDRBS1Bgeeprimitive streak1.00infobox
KHDRBS1Bgeeabdominal wall1.00infobox
KHDRBS1Bgeehuman fetus1.00infobox
KHDRBS1Bgeeatrium1.00infobox
KHDRBS1BioGPSMore reference expression data1.00infobox
KHDRBS1Chr.Chromosome 1 (human)1.00infobox
KHDRBS1Chr.Chromosome 4 (mouse)1.00infobox
KHDRBS1DatabasesNCBI: entry; OMA: entry1.00infobox
KHDRBS1End32,060,850 bp1.00infobox
KHDRBS1End129,636,096 bp1.00infobox
KHDRBS1EnsemblENSG000001217741.00infobox
KHDRBS1Entrez106571.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around KHDRBS1 bring nearby vocabulary together. In this analysis, examples include Signal, Function and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • KHDRBS1
    • Signal
    • Function
    • Location
    • Transduction
    • Binding
    • Chromosome
    • Domain
    • Bp
    • Chr
    • Human
    • Rna
    • Rna-binding
  • khdrbs1
    • Signal
    • Function
    • Location
    • Transduction
    • Binding
    • Chromosome
    • Domain
    • Bp
    • Chr
    • Human
    • Rna
    • Rna-binding
  • protein
    • Signal
    • Rna
    • Cellular
    • Binding
    • Cell
    • Expression
    • Rna-binding
    • Khdrbs1
    • Processes
    • Transduction
    • Human
    • Alternative
  • gene
    • Kh
    • Human
    • Signal
    • Khdrbs1
    • Location
    • Chromosome
    • Domain
    • Protein
    • Bp
    • Chr
    • Rna
    • Rna-binding
  • alternative splicing
    • Splicing
    • Sam68
    • Rna
    • Cellular
    • Processes
    • Cd44
    • Exon
    • Regulate
    • Cell
    • Shown
    • Protein
    • Function
  • cell cycle
    • Expression
    • Cellular
    • Protein
    • Cd44
    • Human
    • Rna
    • Shown
    • Gene
    • Splicing
    • Function
    • Khdrbs1
    • Location
  • human immunodeficiency virus
    • Chromosome
    • Bp
    • Chr
    • Location
    • Band
    • Rna
    • Function
    • Khdrbs1
    • Mouse
    • Transduction
    • Binding
    • Domain
  • signal transduction
    • Binding
    • Signal
    • Transduction
    • Cellular
    • Function
    • Khdrbs1
    • Location
    • Rna
    • Chromosome
    • Domain
    • Kh
    • Bp

Connections between topic areas Semantic bridges

For KHDRBS1, one of the stronger structural bridges in this analysis connects KHDRBS1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
KHDRBS1Clinical significance · splits 20 ⟂ 21
KHDRBS1Overview · splits 33 ⟂ 8
KHDRBS1Gene knockout studies · splits 34 ⟂ 7
KHDRBS1Function · splits 37 ⟂ 4

Map overview Semantic statistics

KHDRBS1

Nodes41
Edges40
Triples104
Avg. degree1.95
Density0.04878
Components1

Source & methodology

TTTA analyzes the structure around KHDRBS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Clinical significance & Gene knockout studies, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — KHDRBS1 · EN edition · Analysis: TopicsToTalkAbout

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