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PLD2

Phospholipase D2 is an enzyme that in humans is encoded by the PLD2 gene.

Interactions, Function & Mechanism of activation

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Interactions

11 related topics

Function

6 related topics

Mechanism of activation

2 related topics

Inhibitors

1 related topics

Key facts & relationships

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3.1.4.4
Aliases
PLD2, phospholipase D2, PLD1C
Band
17p13.2 · 11 B3|11 42.99 cM
Bgee
skin of leg · right hemisphere of cerebellum · ectocervix · right ovary · skin of abdomen
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Function

Mechanism of activation

Interactions

Inhibitors

  • PLD1 Phospholipase D1

Advanced semantic analysis

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Map overview Semantic statistics

PLD2

Nodes28
Edges27
Triples97
Avg. degree1.93
Density0.071429
Components1

How this topic connects Entity context

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PLD2

Top relations

Bgee · 20
PLD2 → ankle, apex of heart, choroid plexus of fourth ventricle, dentate gyrus of hippocampal formation granule cell, ectocervix, esophagus, left ovary, lip, minor salivary glands, primary oocyte, right hemisphere of cerebellum, right ovary, secondary oocyte, skeletal muscle tissue, skin of abdomen, skin of leg, tibial nerve, ventricular zone, vestibular membrane of cochlear duct, zygote
Gene ontology · 20
PLD2 → catalytic activity, cell motility, cytoskeleton organization, endoplasmic reticulum membrane, Fc-gamma receptor signaling pathway involved in phagocytosis, Golgi apparatus, hydrolase activity, inositol lipid-mediated signaling, lipid catabolic process, lipid metabolism, membrane, N-acylphosphatidylethanolamine-specific phospholipase D activity, phosphatidic acid biosynthetic process, phosphatidylinositol binding, phospholipase D activity, plasma membrane, presynapse, protein binding, small GTPase mediated signal transduction, synaptic vesicle recycling
RNA expression pattern · 20
PLD2 → ankle, apex of heart, choroid plexus of fourth ventricle, dentate gyrus of hippocampal formation granule cell, ectocervix, esophagus, left ovary, lip, minor salivary glands, primary oocyte, right hemisphere of cerebellum, right ovary, secondary oocyte, skeletal muscle tissue, skin of abdomen, skin of leg, tibial nerve, ventricular zone, vestibular membrane of cochlear duct, zygote
related to Interactions · 10
PLD2 → Aldolase, Aldrich, Amphiphysin, ARF1, BIN1, Caveolin, Glyceraldehyde, PLCG1, PRKCD, Src
related to Mechanism of activation · 5
PLD2 → PC, PIP2, Scaffolding, The, When PIP2
Band · 2
PLD2 → 11 B3|11 42.99 cM, 17p13.2
Chr. · 2
PLD2 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
PLD2 → 4,823,434 bp, 70,448,936 bp
3.1.4.4 · 1
PLD2 → ↗
Aliases · 1
PLD2 → PLD2, phospholipase D2, PLD1C

Important terminology Word statistics

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Important terminology

bp chr human band gene chromosome 17 phospholipase enzyme lipid location function mouse d2 pc plds substrate rafts pip2 activity

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PLD23.1.4.41.00infobox
PLD2AliasesPLD2, phospholipase D2, PLD1C1.00infobox
PLD2Band17p13.21.00infobox
PLD2Band11 B3|11 42.99 cM1.00infobox
PLD2Bgeeskin of leg1.00infobox
PLD2Bgeeright hemisphere of cerebellum1.00infobox
PLD2Bgeeectocervix1.00infobox
PLD2Bgeeright ovary1.00infobox
PLD2Bgeeskin of abdomen1.00infobox
PLD2Bgeeminor salivary glands1.00infobox
PLD2Bgeeleft ovary1.00infobox
PLD2Bgeetibial nerve1.00infobox
PLD2Bgeeapex of heart1.00infobox
PLD2Bgeeventricular zone1.00infobox
PLD2Bgeelip1.00infobox
PLD2Bgeeesophagus1.00infobox
PLD2Bgeezygote1.00infobox
PLD2Bgeesecondary oocyte1.00infobox
PLD2Bgeeankle1.00infobox
PLD2Bgeeprimary oocyte1.00infobox
PLD2Bgeevestibular membrane of cochlear duct1.00infobox
PLD2Bgeechoroid plexus of fourth ventricle1.00infobox
PLD2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PLD2Bgeeskeletal muscle tissue1.00infobox
PLD2BioGPSMore reference expression data1.00infobox
PLD2Chr.Chromosome 17 (human)1.00infobox
PLD2Chr.Chromosome 11 (mouse)1.00infobox
PLD2DatabasesNCBI: entry; OMA: entry1.00infobox
PLD2End4,823,434 bp1.00infobox
PLD2End70,448,936 bp1.00infobox

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