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Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the MITF gene.
The analysis highlights The LysRS-Ap4A-MITF signaling pathway, Phosphorylation and Translational regulation as prominent areas in the source structure around Microphthalmia-associated transcription factor.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Microphthalmia-associated transcription factor shows recurring relationship patterns in the source. For example, Microphthalmia-associated transcription factor → bone remodeling, camera-type eye development, canonical Wnt signaling pathway involved in negative regulation of apoptotic process, cell differentiation, cell fate commitment, chromatin binding, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, E-box binding, melanocyte differentiation, multicellular organism development, negative regulation of apoptotic process, negative regulation of cell migration, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus, osteoclast differentiation Another extracted example is Microphthalmia-associated transcription factor → atrioventricular valve, ciliary body, decidua, deltoid muscle, Epithelium of choroid plexus, gastrula, glutes, iris, myocardium, myocardium of left ventricle, pineal gland, retinal pigment epithelium, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, stria vascularis, urethra, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
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TTTA extracted 107 structured relationships around Microphthalmia-associated transcription factor. Examples in this analysis include Microphthalmia-associated transcription factor → Aliases → MITF, CMM8, MI, WS2, WS2A, bHLHe32, microphthalmia-associated transcription factor, melanogenesis associated transcription factor, COMMAD, melanocyte inducing transcription fact… and Microphthalmia-associated transcription factor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4C7N. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Microphthalmia-associated transcription factor | Aliases | MITF, CMM8, MI, WS2, WS2A, bHLHe32, microphthalmia-associated transcription factor, melanogenesis associated transcription factor, COMMAD, melanocyte inducing transcription fact… | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4C7N | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Band | 3p13 | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Band | 6 D3|6 45.05 cM | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | retinal pigment epithelium | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | right ventricle | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | glutes | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | myocardium | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | vastus lateralis muscle | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | myocardium of left ventricle | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | deltoid muscle | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | urethra | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | pineal gland | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | gastrula | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | decidua | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | iris | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | ciliary body | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | stria vascularis | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Bgee | atrioventricular valve | 1.00 | infobox |
| Microphthalmia-associated transcription factor | BioGPS | More reference expression data | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Microphthalmia-associated transcription factor | End | 69,968,336 bp | 1.00 | infobox |
| Microphthalmia-associated transcription factor | End | 97,998,310 bp | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Ensembl | ENSG00000187098 | 1.00 | infobox |
| Microphthalmia-associated transcription factor | Entrez | 4286 | 1.00 | infobox |
The concept neighborhoods around Microphthalmia-associated transcription factor bring nearby vocabulary together. In this analysis, examples include Factor, Transcription and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Microphthalmia-associated transcription factor, one of the stronger structural bridges in this analysis connects Microphthalmia-associated transcription factor with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Microphthalmia-associated transcription factor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as The LysRS-Ap4A-MITF signaling pathway, Phosphorylation & Translational regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Microphthalmia-associated transcription factor · EN edition · Analysis: TopicsToTalkAbout