Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

UBE2I: Interactions, Function & Expression

SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene. It is also sometimes referred to as "ubiquitin conjugating enzyme E2I" or "ubiquitin carrier protein 9", even though these names do not accurately describe its function.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

UBE2I topic overview

The analysis highlights Interactions, Function and Expression as prominent areas in the source structure around UBE2I.

Related topics
41
Source areas
4
Connected nodes
45
Extracted relationships
152
Concept neighborhoods
10
Bridge connections
45

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 25 topics
Function · 12 topics
Expression · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
UBE2I, C358B7.1, P18, UBC9, ubiquitin conjugating enzyme E2 I
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A3S, 1KPS, 1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2O25, 2PE6, 2PX9, 2XWU, 3A4S, 3UIN, 3UIO, 3UIP, 4Y1L, 4W5V,…
Band
16p13.3 · 17|17 A3.3
Bgee
oocyte · ganglionic eminence · left ovary · ventricular zone · monocyte
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Expression

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How UBE2I connects Entity context

The extracted context around UBE2I shows recurring relationship patterns in the source. For example, UBE2I → ATP binding, bHLH transcription factor binding, cell cycle, cell division, chromosome segregation, cytoplasm, cytosol, dendrite, enzyme binding, fibrillar center, global genome nucleotide-excision repair, HLH domain binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear body, nuclear envelope, nucleoplasm, nucleotide binding, nucleus, PML body Another extracted example is UBE2I → Androgen, ATF2, BLMH, DACH1, DAXX, DNMT3A, DNMT3B, ETS1, FHIT, IPO13, MAP3K1, P53, PIAS1, PIAS2, RAD51, RANBP2, RANGAP1, SAE2, SALL1, SUMO1. Use these groups to spot repeated connection types before inspecting the individual relationships.

UBE2I

Top relations

Gene ontology · 46
UBE2I → ATP binding, bHLH transcription factor binding, cell cycle, cell division, chromosome segregation, cytoplasm, cytosol, dendrite, enzyme binding, fibrillar center, global genome nucleotide-excision repair, HLH domain binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear body, nuclear envelope, nucleoplasm, nucleotide binding, nucleus, PML body
related to Interactions · 23
UBE2I → Androgen, ATF2, BLMH, DACH1, DAXX, DNMT3A, DNMT3B, ETS1, FHIT, IPO13, MAP3K1, P53, PIAS1, PIAS2, RAD51, RANBP2, RANGAP1, SAE2, SALL1, SUMO1
related to Function · 19
UBE2I → C-terminal, DNA, E1, E2, E3, For, In, It, Small Ubiquitin-like MOdifier, SUMO, SUMO's, Sumoylation, The, The UBC9, There, This, UBC9, Ubc9's, When SUMO
Bgee · 18
UBE2I → embryo, ganglionic eminence, genital tubercle, left adrenal gland, left ovary, left uterine tube, lip, monocyte, oocyte, right ovary, spermatid, spermatocyte, stromal cell of endometrium, tail of embryo, thymus, ventricular zone, yolk sac, zygote
RNA expression pattern · 18
UBE2I → embryo, ganglionic eminence, genital tubercle, left adrenal gland, left ovary, left uterine tube, lip, monocyte, oocyte, right ovary, spermatid, spermatocyte, stromal cell of endometrium, tail of embryo, thymus, ventricular zone, yolk sac, zygote
related to Clinical significance relevance · 5
UBE2I → HIV, HPV, It, The, UBC9
Band · 2
UBE2I → 16p13.3, 17|17 A3.3
Chr. · 2
UBE2I → Chromosome 16 (human), Chromosome 17 (mouse)
End · 2
UBE2I → 1,327,018 bp, 25,493,596 bp
Aliases · 1
UBE2I → UBE2I, C358B7.1, P18, UBC9, ubiquitin conjugating enzyme E2 I

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene ubc9 bp sumoylation enzyme chr human band chromosome 16 sumo function ubiquitin conjugating process location proteins motif encoded

UBE2I relationships Subject–Predicate–Object triples

TTTA extracted 152 structured relationships around UBE2I. Examples in this analysis include UBE2I → Aliases → UBE2I, C358B7.1, P18, UBC9, ubiquitin conjugating enzyme E2 I and UBE2I → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A3S, 1KPS, 1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2O25, 2PE6, 2PX9, 2XWU, 3A4S, 3UIN, 3UIO, 3UIP, 4Y1L, 4W5V,…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
UBE2IAliasesUBE2I, C358B7.1, P18, UBC9, ubiquitin conjugating enzyme E2 I1.00infobox
UBE2IAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A3S, 1KPS, 1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2O25, 2PE6, 2PX9, 2XWU, 3A4S, 3UIN, 3UIO, 3UIP, 4Y1L, 4W5V,…1.00infobox
UBE2IBand16p13.31.00infobox
UBE2IBand17|17 A3.31.00infobox
UBE2IBgeeoocyte1.00infobox
UBE2IBgeeganglionic eminence1.00infobox
UBE2IBgeeleft ovary1.00infobox
UBE2IBgeeventricular zone1.00infobox
UBE2IBgeemonocyte1.00infobox
UBE2IBgeeright ovary1.00infobox
UBE2IBgeethymus1.00infobox
UBE2IBgeestromal cell of endometrium1.00infobox
UBE2IBgeeleft uterine tube1.00infobox
UBE2IBgeeleft adrenal gland1.00infobox
UBE2IBgeezygote1.00infobox
UBE2IBgeetail of embryo1.00infobox
UBE2IBgeegenital tubercle1.00infobox
UBE2IBgeeembryo1.00infobox
UBE2IBgeespermatid1.00infobox
UBE2IBgeespermatocyte1.00infobox
UBE2IBgeeyolk sac1.00infobox
UBE2IBgeelip1.00infobox
UBE2IBioGPSMore reference expression data1.00infobox
UBE2IChr.Chromosome 16 (human)1.00infobox
UBE2IChr.Chromosome 17 (mouse)1.00infobox
UBE2IDatabasesNCBI: entry; OMA: entry1.00infobox
UBE2IEnd1,327,018 bp1.00infobox
UBE2IEnd25,493,596 bp1.00infobox
UBE2IEnsemblENSG000001032751.00infobox
UBE2IEntrez73291.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around UBE2I bring nearby vocabulary together. In this analysis, examples include Search, Location and Ubiquitin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Conjugating
    • Function
    • Ubiquitin
    • Expression
    • Search
    • Gene
    • Ube2i
    • E2
    • Location
    • Chromosome
    • Human
    • Bp
  • protein
    • Sumo
    • Ube2i
    • Expressed
    • Di-glycine
    • E2
    • Function
    • Step
    • Ubc9
    • Ubiquitin
    • Process
    • Sumoylation
    • A3
  • gene
    • Ube2i
    • Location
    • Chromosome
    • Human
    • Ubc9
    • Bp
    • Chr
    • A3
    • End
    • Expression
    • Mouse
    • Search
  • expression
    • Search
    • E2
    • Function
    • Location
    • Ubiquitin
    • Chromosome
    • Human
    • Bp
    • Chr
    • A3
    • Cell
    • End
  • function
    • Ubiquitin
    • Expression
    • Search
    • E2
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Gene
    • Ube2i
    • A3
  • UBE2I
    • Search
    • Location
    • Ubiquitin
    • Human
    • Sumoylation
    • A3
    • Cell
    • End
    • Expressed
    • Interact
    • Mouse
    • Band
  • ube2i
    • Search
    • Location
    • Ubiquitin
    • Human
    • Sumoylation
    • A3
    • Cell
    • End
    • Expressed
    • Interact
    • Mouse
    • Band
  • small ubiquitin-like modifier (sumo)
    • Di-glycine
    • Step
    • Sumoylation
    • Process
    • Proteins
    • Ubiquitin
    • Motif
    • Ube2i
    • Ubc9

Connections between topic areas Semantic bridges

For UBE2I, one of the stronger structural bridges in this analysis connects UBE2I with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
UBE2IInteractions · splits 20 ⟂ 26
UBE2IFunction · splits 33 ⟂ 13
UBE2IOverview · splits 43 ⟂ 3
UBE2IExpression · splits 43 ⟂ 3

Map overview Semantic statistics

UBE2I

Nodes46
Edges45
Triples152
Avg. degree1.96
Density0.043478
Components1

Source & methodology

TTTA analyzes the structure around UBE2I to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Expression, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — UBE2I · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.