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TFE3: Geography, Interactions & Function

Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene.

Language: English [EN]
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TFE3 topic overview

The analysis highlights Geography, Interactions and Function as prominent areas in the source structure around TFE3.

Related topics
9
Source areas
4
Connected nodes
13
Extracted relationships
87
Concept neighborhoods
9
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Function · 2 topics
Overview · 2 topics
Translocations · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3, MRXSPF
Band
Xp11.23 · X A1.1|X 3.5 cM
Bgee
inferior olivary nucleus · dorsal motor nucleus of vagus nerve · olfactory bulb · seminal vesicula · stromal cell of endometrium
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Translocations

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TFE3 connects Entity context

The extracted context around TFE3 shows recurring relationship patterns in the source. For example, TFE3 → adaptive immune response, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, humoral immune response, immune system process, negative regulation of cold-induced thermogenesis, nucleoplasm, nucleus, positive regulation of cell adhesion, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, protein dimerization activity, regulation of osteoclast differentiation, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription by RNA polymerase II Another extracted example is TFE3 → ankle, cartilage tissue, cumulus cell, dorsal motor nucleus of vagus nerve, epiblast, external globus pallidus, granulocyte, inferior olivary nucleus, left uterine tube, molar, olfactory bulb, primary oocyte, right adrenal cortex, secondary oocyte, seminal vesicula, stromal cell of endometrium, thin ascending limb of loop of Henle, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

TFE3

Top relations

Gene ontology · 21
TFE3 → adaptive immune response, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, humoral immune response, immune system process, negative regulation of cold-induced thermogenesis, nucleoplasm, nucleus, positive regulation of cell adhesion, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, protein dimerization activity, regulation of osteoclast differentiation, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription by RNA polymerase II
Bgee · 19
TFE3 → ankle, cartilage tissue, cumulus cell, dorsal motor nucleus of vagus nerve, epiblast, external globus pallidus, granulocyte, inferior olivary nucleus, left uterine tube, molar, olfactory bulb, primary oocyte, right adrenal cortex, secondary oocyte, seminal vesicula, stromal cell of endometrium, thin ascending limb of loop of Henle, yolk sac, zygote
RNA expression pattern · 19
TFE3 → ankle, cartilage tissue, cumulus cell, dorsal motor nucleus of vagus nerve, epiblast, external globus pallidus, granulocyte, inferior olivary nucleus, left uterine tube, molar, olfactory bulb, primary oocyte, right adrenal cortex, secondary oocyte, seminal vesicula, stromal cell of endometrium, thin ascending limb of loop of Henle, yolk sac, zygote
related to Function · 3
TFE3 → E3, Henthorn, OMIM
related to Translocations · 3
TFE3 → PRCC, RCC, Xp11
Band · 2
TFE3 → X A1.1|X 3.5 cM, Xp11.23
Chr. · 2
TFE3 → X chromosome (human), X chromosome (mouse)
End · 2
TFE3 → 49,043,410 bp, 7,641,441 bp
related to Interactions · 2
TFE3 → E2F3, Microphthalmia-associated
Aliases · 1
TFE3 → TFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3, MRXSPF

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band chromosome transcription factor location protein mouse function binding external 043 410 end 49 a1 641

TFE3 relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around TFE3. Examples in this analysis include TFE3 → Aliases → TFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3, MRXSPF and TFE3 → Band → Xp11.23. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TFE3AliasesTFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3, MRXSPF1.00infobox
TFE3BandXp11.231.00infobox
TFE3BandX A1.1|X 3.5 cM1.00infobox
TFE3Bgeeinferior olivary nucleus1.00infobox
TFE3Bgeedorsal motor nucleus of vagus nerve1.00infobox
TFE3Bgeeolfactory bulb1.00infobox
TFE3Bgeeseminal vesicula1.00infobox
TFE3Bgeestromal cell of endometrium1.00infobox
TFE3Bgeesecondary oocyte1.00infobox
TFE3Bgeeleft uterine tube1.00infobox
TFE3Bgeecartilage tissue1.00infobox
TFE3Bgeeexternal globus pallidus1.00infobox
TFE3Bgeeright adrenal cortex1.00infobox
TFE3Bgeezygote1.00infobox
TFE3Bgeegranulocyte1.00infobox
TFE3Bgeeprimary oocyte1.00infobox
TFE3Bgeethin ascending limb of loop of Henle1.00infobox
TFE3Bgeemolar1.00infobox
TFE3Bgeeepiblast1.00infobox
TFE3Bgeecumulus cell1.00infobox
TFE3Bgeeankle1.00infobox
TFE3Bgeeyolk sac1.00infobox
TFE3BioGPSMore reference expression data1.00infobox
TFE3Chr.X chromosome (human)1.00infobox
TFE3Chr.X chromosome (mouse)1.00infobox
TFE3DatabasesNCBI: entry; OMA: entry1.00infobox
TFE3End49,043,410 bp1.00infobox
TFE3End7,641,441 bp1.00infobox
TFE3EnsemblENSG000000683231.00infobox
TFE3Entrez70301.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TFE3 bring nearby vocabulary together. In this analysis, examples include Transcription, Gene and Binding. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Tfe3
    • Transcription
    • Chromosome
    • Human
    • A1
    • Binding
    • Bp
    • Chr
    • End
    • Enhancer
    • External
  • microphthalmia-associated transcription factor
    • Tfe3
    • Transcription
    • Gene
    • Binding
    • Enhancer
    • External
    • Function
    • Omim
    • Protein
    • Translocations
    • Location
    • Chromosome
  • function
    • Binding
    • Enhancer
    • External
    • Omim
    • Translocations
    • Location
    • Tfe3
    • Transcription
    • Cell
    • Chromosome
    • Expressed
    • Gene
  • TFE3
    • Transcription
    • Gene
    • Binding
    • Enhancer
    • External
    • Function
    • Omim
    • Translocations
    • Location
    • Chromosome
    • Human
    • Bp
  • tfe3
    • Transcription
    • Gene
    • Binding
    • Enhancer
    • External
    • Function
    • Omim
    • Translocations
    • Location
    • Chromosome
    • Human
    • Bp
  • protein
    • Tfe3
    • Transcription
    • Cell
    • Encoded
    • Expressed
    • Gene
    • Humans
    • A1
    • Binding
    • End
    • Enhancer
    • External
  • transcription factors
    • Omim
    • Translocations
    • Location
    • Cell
    • Expressed
    • A1
    • End
    • Mouse
    • Xp11
    • Band
  • interactions
    • Reading
    • References
    • Omim
    • Translocations
    • Location
    • Tfe3
    • Transcription
    • Human

Connections between topic areas Semantic bridges

For TFE3, one of the stronger structural bridges in this analysis connects TFE3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TFE3Interactions · splits 9 ⟂ 5
TFE3Overview · splits 11 ⟂ 3
TFE3Function · splits 11 ⟂ 3

Map overview Semantic statistics

TFE3

Nodes14
Edges13
Triples87
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around TFE3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TFE3 · EN edition · Analysis: TopicsToTalkAbout

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