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Importin: Regions, Structure & Human importin genes

Importin is a type of karyopherin involved in the nuclear transport of moving protein molecules from a cell's cytoplasm to the nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS).

Language: English [EN]
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Importin topic overview

The analysis highlights Regions, Structure and Human importin genes as prominent areas in the source structure around Importin.

Related topics
74
Source areas
6
Connected nodes
80
Extracted relationships
126
Concept neighborhoods
22
Bridge connections
80

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 15 topics
Overview · 14 topics
Human importin genes · 13 topics
Disease · 12 topics
Discovery · 10 topics
Nuclear protein import cycle · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
HGNC
6394
Locus
Chr. 3 q21.1
NCBI gene
3836
OMIM
600686
RefSeq
NP_002255

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Structure

Nuclear protein import cycle

Disease

Human importin genes

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Importin connects Entity context

The extracted context around Importin shows recurring relationship patterns in the source. For example, Importin → Dirk Görlich, Enno Hartmann, Importin-α, Importin-β, IPO4, IPO7, It, Max Delbrück Center, Michael Rexach, Molecular Medicine, NLS, Other, Ran, Since, SRP1p, TC4, The, These, Xenopus Another extracted example is Importin → Although, IPO11, IPO13Karyopherin-α, IPO4, IPO5, IPO7, IPO8, IPO9, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KPNA6Karyopherin-β, KPNB1, Note, Various. Use these groups to spot repeated connection types before inspecting the individual relationships.

Importin

Top relations

related to Discovery · 19
Importin → Dirk Görlich, Enno Hartmann, Importin-α, Importin-β, IPO4, IPO7, It, Max Delbrück Center, Michael Rexach, Molecular Medicine, NLS, Other, Ran, Since, SRP1p, TC4, The, These, Xenopus
related to Human importin genes · 17
Importin → Although, IPO11, IPO13Karyopherin-α, IPO4, IPO5, IPO7, IPO8, IPO9, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KPNA6Karyopherin-β, KPNB1, Note, Various
related to Recycling · 14
Importin → CAS, Finally, GAP, GEF, GTP, Importin-β, In, It, Once, Ran, Ran-GDP, Ran-GTP, Ran-GTP/CAS, RanGAP
related to Importin-α · 12
Importin → ARM, As, C-terminus, IBB, Importin-α, Importin-β, N-terminal, N-terminus, NLS, The, These, This
related to Cargo release · 10
Importin → IBB, In, NLS, NLS-binding, Now, Nup2, Nup50, The, The N-terminal, This
related to Importin-β · 9
Importin → Crystallographic, Each, FG, HEAT, Importin-β, In, It, Phe-Gly, The
related to Cargo transport · 7
Importin → Importin-β, NPC, Once, Ran-GTP, Ras-family GTPase, The, This
related to External links · 6
Importin → Importins, Medicine Medical Subject Headings, MeSH, Month Importins, National Library, PDB Molecule
related to Disease · 4
Importin → As, Drosophila, Importins, There
related to Neuronal functions · 4
Importin → After, Subcellular, These, UTR

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein importin-α importin-β cargo nucleus proteins cytoplasm nls nuclear binding transport also structure form complex two bind import ran-gtp ran

Importin relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around Importin. Examples in this analysis include Importin → Domains → InterPro and Importin → HGNC → 6394. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ImportinDomainsInterPro1.00infobox
ImportinHGNC63941.00infobox
ImportinLocusChr. 3 q21.11.00infobox
ImportinNCBI gene38361.00infobox
ImportinOMIM6006861.00infobox
ImportinRefSeqNP_0022551.00infobox
ImportinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
ImportinStructuresSwiss-model1.00infobox
ImportinSymbolKPNA11.00infobox
ImportinUniProtP522941.00infobox
Importinis atype of karyopherin involved in the nuclear transport of moving protein molecules from a cell's cytoplasm to the nucleus0.90text
Nup2instance ofspecific release factors0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Importin bring nearby vocabulary together. In this analysis, examples include Β1, Proteins and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Importin
    • Β1
    • Proteins
    • Function
    • Protein
    • Cargo
    • Import
    • Nucleus
    • Structure
    • Also
    • Cytoplasm
    • Importin-β
    • Nuclear
  • importin
    • Β1
    • Proteins
    • Function
    • Protein
    • Cargo
    • Import
    • Nucleus
    • Structure
    • Also
    • Cytoplasm
    • Importin-β
    • Nuclear
  • nuclear transport
    • Localization
    • Import
    • Pore
    • Protein
    • Nuclear
    • Transport
    • Nucleus
    • Order
    • Ran
    • Importin-β
    • Form
    • Nls
  • protein
    • Nucleus
    • Cargo
    • Importin-β
    • Importin-α
    • Function
    • Import
    • Transport
    • Nls
    • Adaptor
    • Localization
    • Region
    • Release
  • nucleus
    • Protein
    • Complex
    • Transport
    • Cargo
    • Importin-α
    • Proteins
    • Importin-β
    • Gtp
    • Pore
    • Localization
    • Order
    • Ran
  • nuclear localization sequences
    • Pore
    • Localization
    • Nuclear
    • Import
    • Nls
    • Protein
    • Transport
    • Function
    • Nucleus
    • Importin-β
    • Adaptor
    • Heterodimer
  • nuclear localization signal
    • Pore
    • Localization
    • Nuclear
    • Import
    • Nls
    • Protein
    • Transport
    • Function
    • Nucleus
    • Importin-β
    • Adaptor
    • Heterodimer
  • adaptor protein
    • Nucleus
    • Cargo
    • Importin-β
    • Importin-α
    • Function
    • Heterodimer
    • Pore
    • Nls
    • Import
    • Localization
    • Repeats
    • Transport

Connections between topic areas Semantic bridges

For Importin, one of the stronger structural bridges in this analysis connects Importin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ImportinStructure · splits 65 ⟂ 16
ImportinOverview · splits 66 ⟂ 15
ImportinHuman importin genes · splits 67 ⟂ 14
ImportinDisease · splits 68 ⟂ 13
ImportinDiscovery · splits 70 ⟂ 11
ImportinNuclear protein import cycle · splits 70 ⟂ 11

Map overview Semantic statistics

Importin

Nodes81
Edges80
Triples126
Avg. degree1.98
Density0.024691
Components1

Source & methodology

TTTA analyzes the structure around Importin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Structure & Human importin genes, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Importin · EN edition · Analysis: TopicsToTalkAbout

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