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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a resident cell that develops and lives in connective or mucosal tissue and contains many small secretory granules for the storage and release of histamine, heparin and other mediators. Derived from myeloid progenitor cells, mast cells are granulocytes, a type of white blood cell, and part of the…

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FMA
66784
Latin
mastocytus
MeSH
D008407
System
Immune system
TH
H2.00.03.0.01010

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Map overview Semantic statistics

Mast cell

Nodes269
Edges268
Triples255
Avg. degree1.99
Density0.007435
Components1

How this topic connects Entity context

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Mast cell

Top relations

related to Mast cell mediators · 29
Mast cell → CD63, CPA3, CRH, Examples, GM-CSF, GnRH, IL-1, IL-18, IL-3, IL-4, IL-6, In, LTB4, LTC4, Mast, MCP-1, Newly, NGF, PAF, PDGF
related to Parasitic infections · 21
Mast cell → Due, FcεRI, Giardia, IgE, IgE-mediated, IL-13, IL-4, IL-5, Interactions, MAMPs, Mast, MC, MCs, PAMPs, Parasites, Parasitic, Strongyloidiasis, The, These, Trichinella
has treatment · 19
Mast cell → Avapritinib, Bilastine, Cetirizine, Fexofenadine, GCs, Given, Glucocorticosteroids, H1, IgE, Imatinib, KIT, Levocetirizine, Mast, MCs, Midostaurin, Omalizumab, Other, Rupatadine, These
related to history · 18
Mast cell → As, By, Friedrich, Holmgren, In, Mast, Mastzellen, MCs, Paul Ehrlich, Recklinghausen, Riley, Rocha, Silva, That, These, They, West, Wilander
related to Development · 14
Mast cell → CMPs, GMPs, HSCs, In, Leonard Herzenberg, Leonore Herzenberg, Mast, Mature MCs, MCps, MCs, MPPs, Once, Specific, The
related to Signaling pathways for mast cell activation · 14
Mast cell → Activation, Ags, As, Complement, DAMPs, Fc, FcεRI, G-protein, IgE, Mast, MCs, PAMPs, Specific, The
related to Allergic disease · 13
Mast cell → Allergens, Allergies, FcεRI, Icatibant, IgE, IgE-independent, In, MCs, MRGPRX2, Other, TH2, These, Type
related to Mast cell activation disorders · 11
Mast cell → Edition Classification, Haematolymphoid Tumours, ICC, International Consensus Classification, Mast, MCAD, MCAD's, MCAS, The, The World Health Organization, WHO
related to Histological staining · 10
Mast cell → Alcian Blue, Ehrlich, Giemsa, In, It, Mast, Mature, Safranin, Since, Toluidine
related to Chronic urticaria · 9
Mast cell → Chronic, CIndU, CSU, CU, FcεRI, IgE, IIb CSU, In, Symptoms

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Important terminology

mast cells cell activation mcs histamine mediators immune granules ige release progenitors fcεri mastocytosis may mcas skin tryptase tissue receptor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mast cellFMA667841.00infobox
Mast cellLatinmastocytus1.00infobox
Mast cellMeSHD0084071.00infobox
Mast cellSystemImmune system1.00infobox
Mast cellTHH2.00.03.0.010101.00infobox
mice compared to primatesinstance ofthere are differences in the embryonic development of vertebrates0.80text
histamineinstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text
serotonininstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text
and leukotrienesinstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text
followed over a period of hours by the secretion of cytokinesinstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text
chemokinesinstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text
and growth factors.FcεRI regulates the Aginstance ofActivation leads within minutes to degranulation of mast cells and the release of mediators0.80text

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