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ATP-dependent RNA helicase DDX3X is an enzyme that in humans is encoded by the DDX3X gene.
The analysis highlights Role in cancer, Function and Clinical significance as prominent areas in the source structure around DDX3X.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around DDX3X shows recurring relationship patterns in the source. For example, DDX3X → apoptotic process, ATP binding, ATPase activity, cadherin binding, cellular response to arsenic-containing substance, cellular response to osmotic stress, chromosome segregation, CTPase activity, cytoplasm, cytoplasmic stress granule, cytosol, cytosolic small ribosomal subunit, DNA binding, DNA duplex unwinding, DNA helicase activity, eukaryotic initiation factor 4E binding, eukaryotic translation initiation factor 3 complex, extracellular exosome, extracellular region, extrinsic apoptotic signaling pathway via death domain receptors Another extracted example is DDX3X → cumulus cell, Epithelium of choroid plexus, epithelium of colon, epithelium of stomach, genital tubercle, human fetus, lacrimal gland, lactiferous duct, mandibular prominence, maxillary prominence, mucosa of paranasal sinus, oocyte, palpebral conjunctiva, primitive streak, secondary oocyte, skin of hip, sperm, tail of embryo, tibia, ureter. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp helicase expression translation chr human band melanoma chromosome rna cells activity mrna location vemurafenib mitf binding protein nuclear
TTTA extracted 174 structured relationships around DDX3X. Examples in this analysis include DDX3X → 3.6.4.13 → ↗ and DDX3X → Aliases → DDX3X, DBX, DDX14, DDX3, HLP2, CAP-Rf, MRX102, DEAD-box helicase 3, X-linked, DEAD-box helicase 3 X-linked, MRXSSB. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DDX3X | 3.6.4.13 | ↗ | 1.00 | infobox |
| DDX3X | Aliases | DDX3X, DBX, DDX14, DDX3, HLP2, CAP-Rf, MRX102, DEAD-box helicase 3, X-linked, DEAD-box helicase 3 X-linked, MRXSSB | 1.00 | infobox |
| DDX3X | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I4I, 2JGN, 3JRV, 4O2C, 4O2E, 4O2F, 4PX9, 4PXA, 5E7J, 5E7M, 5E7I | 1.00 | infobox |
| DDX3X | Band | Xp11.4 | 1.00 | infobox |
| DDX3X | Band | X A1.1|X 8.17 cM | 1.00 | infobox |
| DDX3X | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| DDX3X | Bgee | oocyte | 1.00 | infobox |
| DDX3X | Bgee | sperm | 1.00 | infobox |
| DDX3X | Bgee | secondary oocyte | 1.00 | infobox |
| DDX3X | Bgee | palpebral conjunctiva | 1.00 | infobox |
| DDX3X | Bgee | lactiferous duct | 1.00 | infobox |
| DDX3X | Bgee | tibia | 1.00 | infobox |
| DDX3X | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| DDX3X | Bgee | skin of hip | 1.00 | infobox |
| DDX3X | Bgee | epithelium of colon | 1.00 | infobox |
| DDX3X | Bgee | maxillary prominence | 1.00 | infobox |
| DDX3X | Bgee | cumulus cell | 1.00 | infobox |
| DDX3X | Bgee | human fetus | 1.00 | infobox |
| DDX3X | Bgee | tail of embryo | 1.00 | infobox |
| DDX3X | Bgee | mandibular prominence | 1.00 | infobox |
| DDX3X | Bgee | primitive streak | 1.00 | infobox |
| DDX3X | Bgee | lacrimal gland | 1.00 | infobox |
| DDX3X | Bgee | genital tubercle | 1.00 | infobox |
| DDX3X | Bgee | epithelium of stomach | 1.00 | infobox |
| DDX3X | Bgee | ureter | 1.00 | infobox |
| DDX3X | BioGPS | More reference expression data | 1.00 | infobox |
| DDX3X | Chr. | X chromosome (human) | 1.00 | infobox |
| DDX3X | Chr. | X chromosome (mouse) | 1.00 | infobox |
| DDX3X | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| DDX3X | End | 41,364,472 bp | 1.00 | infobox |
The concept neighborhoods around DDX3X bring nearby vocabulary together. In this analysis, examples include Helicase, Activity and Expression. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For DDX3X, one of the stronger structural bridges in this analysis connects DDX3X with Role in cancer. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around DDX3X to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role in cancer, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — DDX3X · EN edition · Analysis: TopicsToTalkAbout