TFEB

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Explore the main themes, entities and connections around TFEB. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Lysosomal Biogenesis Transcription factor Autophagy Lysosomal storage diseases

23 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TFEB, ALPHABHLHE35, TCFEB, transcription factor EB
Band: 6p21.1 · 17 C|17 23.99 cM
Bgee: muscle of thigh · gastrocnemius muscle · apex of heart · granulocyte · blood
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 17 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Lysosomal Lysosome
Biogenesis
Transcription factor
Autophagy
Lysosomal storage diseases
Nicotinic acid adenine dinucleotide phosphate
Inflammatory Inflammation
Cytokines Cytokine
Huntington's Huntington's disease
Parkinson's Parkinson's disease
Alzheimer's diseases Alzheimer's disease
PGC1-alpha PPARGC1A
Htt Huntingtin
Neurotoxicity
Birt–Hogg–Dubé syndrome
MTORC1
ERK2 MAPK1
14-3-3 proteins
AKT/PKB Protein kinase B
Batten disease
Sanfilippo syndrome
Trex1
MTORC1 MTOR

Advanced semantic analysis

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Map overview Semantic statistics

Nodes28

Edges27

Triples90

Avg. degree1.93

Density0.071429

Components1

How this topic connects Entity context

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TFEB

Top relations

Gene ontology · 18

TFEB → adaptive immune response, autophagy, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, humoral immune response, immune system process, lysosome localization, lysosome organization, nucleus, positive regulation of autophagy, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein dimerization activity, regulation of transcription, DNA-templated, transcription, DNA-templated

Bgee · 17

TFEB → ankle, apex of heart, blood, C1 segment, ciliary body, esophagus, gastrocnemius muscle, granulocyte, inferior ganglion of vagus nerve, inferior olivary nucleus, iris, monocyte, muscle of thigh, spleen, temporal muscle, triceps brachii muscle, vastus lateralis muscle

RNA expression pattern · 17

related to Function · 10

TFEB → Alzheimer's, Ca2, Huntington's, In, It, NAADP, Parkinson's, PGC1-alpha, Upon, Viral-mediated TFEB

Band · 2

TFEB → 17 C|17 23.99 cM, 6p21.1

Chr. · 2

TFEB → Chromosome 17 (mouse), Chromosome 6 (human)

End · 2

TFEB → 41,736,259 bp, 48,103,344 bp

Aliases · 1

TFEB → TFEB, ALPHABHLHE35, TCFEB, transcription factor EB

BioGPS · 1

TFEB → More reference expression data

Databases · 1

TFEB → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

lysosomal bp gene chr human band autophagy mouse transcription factor chromosome biogenesis protein location nuclear mtorc1 expression activity cellular eb

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
TFEB	Aliases	TFEB, ALPHABHLHE35, TCFEB, transcription factor EB	1.00	infobox
TFEB	Band	6p21.1	1.00	infobox
TFEB	Band	17 C\|17 23.99 cM	1.00	infobox
TFEB	Bgee	muscle of thigh	1.00	infobox
TFEB	Bgee	gastrocnemius muscle	1.00	infobox
TFEB	Bgee	apex of heart	1.00	infobox
TFEB	Bgee	granulocyte	1.00	infobox
TFEB	Bgee	blood	1.00	infobox
TFEB	Bgee	C1 segment	1.00	infobox
TFEB	Bgee	inferior olivary nucleus	1.00	infobox
TFEB	Bgee	spleen	1.00	infobox
TFEB	Bgee	inferior ganglion of vagus nerve	1.00	infobox
TFEB	Bgee	monocyte	1.00	infobox
TFEB	Bgee	esophagus	1.00	infobox
TFEB	Bgee	triceps brachii muscle	1.00	infobox
TFEB	Bgee	temporal muscle	1.00	infobox
TFEB	Bgee	vastus lateralis muscle	1.00	infobox
TFEB	Bgee	ankle	1.00	infobox
TFEB	Bgee	iris	1.00	infobox
TFEB	Bgee	ciliary body	1.00	infobox
TFEB	BioGPS	More reference expression data	1.00	infobox
TFEB	Chr.	Chromosome 6 (human)	1.00	infobox
TFEB	Chr.	Chromosome 17 (mouse)	1.00	infobox
TFEB	Databases	NCBI: entry; OMA: entry	1.00	infobox
TFEB	End	41,736,259 bp	1.00	infobox
TFEB	End	48,103,344 bp	1.00	infobox
TFEB	Ensembl	ENSG00000112561	1.00	infobox
TFEB	Entrez	7942	1.00	infobox
TFEB	External IDs	OMIM: 600744; MGI: 103270; GeneCards: TFEB	1.00	infobox
TFEB	Gene location (Human)	Gene location (Human)Chr.Chromosome 6 (human)Band6p21.1Start41,683,978 bpEnd41,736,259 bp	1.00	infobox

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