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EIF2A: Measurement, Function & Overview

Eukaryotic translation initiation factor 2A (eIF2A) is a protein that in humans is encoded by the EIF2A gene. The eIF2A protein is not to be confused with eIF2α, a subunit of the heterotrimeric eIF2 complex. Instead, eIF2A functions by a separate mechanism in eukaryotic translation.

Language: English [EN]
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EIF2A topic overview

The analysis highlights Measurement, Function and Overview as prominent areas in the source structure around EIF2A.

Related topics
9
Source areas
2
Connected nodes
11
Extracted relationships
83
Concept neighborhoods
8
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 5 topics
Function · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EIF2A, EIF-2A, MST089, MSTP004, MSTP089, CDA02, eukaryotic translation initiation factor 2A
Band
3q25.1 · 3 D|3 28.58 cM
Bgee
secondary oocyte · tibialis anterior muscle · pancreatic epithelial cell · skin of arm · body of pancreas
BioGPS
More reference expression data
Chr.
Chromosome 3 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EIF2A connects Entity context

The extracted context around EIF2A shows recurring relationship patterns in the source. For example, EIF2A → Achilles tendon, body of pancreas, deltoid muscle, epiblast, esophagus, genital tubercle, hand, lobe of prostate, monocyte, mucosa of ileum, muscle of thigh, myocardium of left ventricle, otolith organ, pancreatic epithelial cell, secondary oocyte, skin of arm, tail of embryo, tibialis anterior muscle, utricle, ventricular zone Another extracted example is EIF2A → blood microparticle, cadherin binding, cytoplasm, cytosolic small ribosomal subunit, eukaryotic translation initiation factor 2 complex, extracellular space, mRNA binding, positive regulation of signal transduction, protein binding, protein biosynthesis, protein phosphorylation, regulation of translation, response to amino acid starvation, ribosome assembly, ribosome binding, SREBP signaling pathway, translation initiation factor activity, translational initiation, tRNA binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

EIF2A

Top relations

Bgee · 20
EIF2A → Achilles tendon, body of pancreas, deltoid muscle, epiblast, esophagus, genital tubercle, hand, lobe of prostate, monocyte, mucosa of ileum, muscle of thigh, myocardium of left ventricle, otolith organ, pancreatic epithelial cell, secondary oocyte, skin of arm, tail of embryo, tibialis anterior muscle, utricle, ventricular zone
RNA expression pattern · 20
EIF2A → Achilles tendon, body of pancreas, deltoid muscle, epiblast, esophagus, genital tubercle, hand, lobe of prostate, monocyte, mucosa of ileum, muscle of thigh, myocardium of left ventricle, otolith organ, pancreatic epithelial cell, secondary oocyte, skin of arm, tail of embryo, tibialis anterior muscle, utricle, ventricular zone
Gene ontology · 19
EIF2A → blood microparticle, cadherin binding, cytoplasm, cytosolic small ribosomal subunit, eukaryotic translation initiation factor 2 complex, extracellular space, mRNA binding, positive regulation of signal transduction, protein binding, protein biosynthesis, protein phosphorylation, regulation of translation, response to amino acid starvation, ribosome assembly, ribosome binding, SREBP signaling pathway, translation initiation factor activity, translational initiation, tRNA binding
related to Function · 4
EIF2A → HCV IRES, It, OMIM, Zoll
Band · 2
EIF2A → 3 D|3 28.58 cM, 3q25.1
Chr. · 2
EIF2A → Chromosome 3 (human), Chromosome 3 (mouse)
End · 2
EIF2A → 150,586,016 bp, 58,464,922 bp
Aliases · 1
EIF2A → EIF2A, EIF-2A, MST089, MSTP004, MSTP089, CDA02, eukaryotic translation initiation factor 2A
BioGPS · 1
EIF2A → More reference expression data
Databases · 1
EIF2A → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp translation chr human band protein eukaryotic gene initiation chromosome factor location mouse 2a subunit complex function 586 016 end

EIF2A relationships Subject–Predicate–Object triples

TTTA extracted 83 structured relationships around EIF2A. Examples in this analysis include EIF2A → Aliases → EIF2A, EIF-2A, MST089, MSTP004, MSTP089, CDA02, eukaryotic translation initiation factor 2A and EIF2A → Band → 3q25.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EIF2AAliasesEIF2A, EIF-2A, MST089, MSTP004, MSTP089, CDA02, eukaryotic translation initiation factor 2A1.00infobox
EIF2ABand3q25.11.00infobox
EIF2ABand3 D|3 28.58 cM1.00infobox
EIF2ABgeesecondary oocyte1.00infobox
EIF2ABgeetibialis anterior muscle1.00infobox
EIF2ABgeepancreatic epithelial cell1.00infobox
EIF2ABgeeskin of arm1.00infobox
EIF2ABgeebody of pancreas1.00infobox
EIF2ABgeeAchilles tendon1.00infobox
EIF2ABgeedeltoid muscle1.00infobox
EIF2ABgeemyocardium of left ventricle1.00infobox
EIF2ABgeemucosa of ileum1.00infobox
EIF2ABgeemonocyte1.00infobox
EIF2ABgeegenital tubercle1.00infobox
EIF2ABgeetail of embryo1.00infobox
EIF2ABgeeventricular zone1.00infobox
EIF2ABgeeepiblast1.00infobox
EIF2ABgeehand1.00infobox
EIF2ABgeemuscle of thigh1.00infobox
EIF2ABgeeotolith organ1.00infobox
EIF2ABgeeutricle1.00infobox
EIF2ABgeelobe of prostate1.00infobox
EIF2ABgeeesophagus1.00infobox
EIF2ABioGPSMore reference expression data1.00infobox
EIF2AChr.Chromosome 3 (human)1.00infobox
EIF2AChr.Chromosome 3 (mouse)1.00infobox
EIF2ADatabasesNCBI: entry; OMA: entry1.00infobox
EIF2AEnd150,586,016 bp1.00infobox
EIF2AEnd58,464,922 bp1.00infobox
EIF2AEnsemblENSG000001448951.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around EIF2A bring nearby vocabulary together. In this analysis, examples include Eukaryotic, Translation and Factor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • EIF2A
    • Eukaryotic
    • Translation
    • Factor
    • Initiation
    • Protein
    • Gene
    • Complex
    • Function
    • Omim
    • Subunit
    • Location
    • Chromosome
  • eif2a
    • Eukaryotic
    • Translation
    • Factor
    • Initiation
    • Protein
    • Gene
    • Complex
    • Function
    • Omim
    • Subunit
    • Location
    • Chromosome
  • eukaryotic translation
    • Eukaryotic
    • Translation
    • Eif2a
    • Factor
    • Initiation
    • Gene
    • 2a
    • Function
    • Omim
    • Location
    • Protein
    • Chromosome
  • protein
    • Complex
    • Subunit
    • Gene
    • Translation
    • Confused
    • Eif2
    • Eif2α
    • Heterotrimeric
    • Humans
    • End
    • Function
    • Mouse
  • gene
    • Initiation
    • Location
    • Chromosome
    • Human
    • Translation
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Omim
    • Protein
  • function
    • Omim
    • Initiation
    • Location
    • Chromosome
    • Gene
    • Human
    • Reading
    • References
    • Translation
    • Bp
    • Chr
    • End
  • eif2
    • Eif2α
    • Heterotrimeric
    • Complex
    • Subunit
    • Protein
    • Eif2a
  • eif2α
    • Heterotrimeric
    • Subunit
    • Protein

Connections between topic areas Semantic bridges

For EIF2A, one of the stronger structural bridges in this analysis connects EIF2A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EIF2AOverview · splits 6 ⟂ 6
EIF2AFunction · splits 7 ⟂ 5

Map overview Semantic statistics

EIF2A

Nodes12
Edges11
Triples83
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around EIF2A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EIF2A · EN edition · Analysis: TopicsToTalkAbout

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