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CFLAR

CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene. Also called c-FLIP (FLICE-like inhibitory protein).

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5 related topics

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Aliases
CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator, cFLIP
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3H11, 3H13, 2N5R
Band
2q33.1 · 1 C1.3|1 29.16 cM
Bgee
right lung · apex of heart · upper lobe of left lung · right auricle of heart · left ventricle
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 1 (mouse)

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Map overview Semantic statistics

CFLAR

Nodes7
Edges6
Triples126
Avg. degree1.71
Density0.285714
Components1

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CFLAR

Top relations

Gene ontology · 58
CFLAR → apoptotic process, CD95 death-inducing signaling complex, cellular response to dexamethasone stimulus, cellular response to epidermal growth factor stimulus, cellular response to estradiol stimulus, cellular response to hypoxia, cellular response to insulin stimulus, cellular response to nitric oxide, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type endopeptidase activity involved in execution phase of apoptosis, cysteine-type peptidase activity, cytoplasm, cytosol, death receptor binding, death-inducing signaling complex, enzyme activator activity, execution phase of apoptosis, membrane raft, negative regulation of apoptotic process
Bgee · 18
CFLAR → aortic valve, apex of heart, ascending aorta, blood, bone marrow cell, ciliary body, epithelium of colon, gastrocnemius muscle, granulocyte, lateral recess, left ventricle, proximal tubule, right auricle of heart, right kidney, right lung, right lung lobe, thymus, upper lobe of left lung
RNA expression pattern · 18
CFLAR → aortic valve, apex of heart, ascending aorta, blood, bone marrow cell, ciliary body, epithelium of colon, gastrocnemius muscle, granulocyte, lateral recess, left ventricle, proximal tubule, right auricle of heart, right kidney, right lung, right lung lobe, thymus, upper lobe of left lung
related to External links · 9
CFLAR → CASP8, FADD-like, Human CFLAR, O15519, Overview, PDB, PDBe-KB, UCSC Genome Browser, UniProt
Band · 2
CFLAR → 1 C1.3|1 29.16 cM, 2q33.1
Chr. · 2
CFLAR → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
CFLAR → 201,176,687 bp, 58,798,043 bp
Aliases · 1
CFLAR → CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator, cFLIP
Available structures · 1
CFLAR → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3H11, 3H13, 2N5R
BioGPS · 1
CFLAR → More reference expression data

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Important terminology

bp human gene chr band protein apoptosis chromosome location casp8 regulator mouse c-flip external pdb uniprot o15519 fadd-like search 176

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CFLARAliasesCFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator, cFLIP1.00infobox
CFLARAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3H11, 3H13, 2N5R1.00infobox
CFLARBand2q33.11.00infobox
CFLARBand1 C1.3|1 29.16 cM1.00infobox
CFLARBgeeright lung1.00infobox
CFLARBgeeapex of heart1.00infobox
CFLARBgeeupper lobe of left lung1.00infobox
CFLARBgeeright auricle of heart1.00infobox
CFLARBgeeleft ventricle1.00infobox
CFLARBgeeepithelium of colon1.00infobox
CFLARBgeeblood1.00infobox
CFLARBgeegranulocyte1.00infobox
CFLARBgeegastrocnemius muscle1.00infobox
CFLARBgeebone marrow cell1.00infobox
CFLARBgeeright kidney1.00infobox
CFLARBgeeascending aorta1.00infobox
CFLARBgeeaortic valve1.00infobox
CFLARBgeeproximal tubule1.00infobox
CFLARBgeeright lung lobe1.00infobox
CFLARBgeeciliary body1.00infobox
CFLARBgeethymus1.00infobox
CFLARBgeelateral recess1.00infobox
CFLARBioGPSMore reference expression data1.00infobox
CFLARChr.Chromosome 2 (human)1.00infobox
CFLARChr.Chromosome 1 (mouse)1.00infobox
CFLARDatabasesNCBI: entry; OMA: entry1.00infobox
CFLAREnd201,176,687 bp1.00infobox
CFLAREnd58,798,043 bp1.00infobox
CFLAREnsemblENSG000000034021.00infobox
CFLAREntrez88371.00infobox

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