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Fas receptor: Regions, Function & Protein

The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is encoded by the FAS gene. Fas was first identified using a monoclonal antibody generated by immunizing mice with the FS-7 cell line. Thus, the…

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Fas receptor topic overview

The analysis highlights Regions, Function and Protein as prominent areas in the source structure around Fas receptor.

Related topics
47
Source areas
6
Connected nodes
53
Extracted relationships
162
Concept neighborhoods
19
Bridge connections
53

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 13 topics
Overview · 8 topics
Protein · 8 topics
Role in apoptosis · 8 topics
Gene · 5 topics
Interactions · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DDF, 3EWT, 3EZQ, 3THM, 3TJE, 2NA7
Band
10q23.31 · 19 C1|19 29.48 cM
Bgee
rectum · left ovary · right ovary · gallbladder · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Protein

Function

Role in apoptosis

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fas receptor connects Entity context

The extracted context around Fas receptor shows recurring relationship patterns in the source. For example, Fas receptor → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, activation-induced cell death of T cells, apoptotic process, apoptotic signaling pathway, B cell mediated immunity, calmodulin binding, CD95 death-inducing signaling complex, cell surface, cellular response to amino acid starvation, cellular response to hyperoxia, cellular response to lithium ion, cellular response to mechanical stimulus, circadian rhythm, cytosol, death-inducing signaling complex, external side of plasma membrane, extracellular exosome, extracellular region, extrinsic apoptotic signaling pathway Another extracted example is Fas receptor → brown adipose tissue, duodenum, epithelium of nasopharynx, gallbladder, granulocyte, intercostal muscle, jejunum, left adrenal cortex, left adrenal gland, left ovary, rectum, right adrenal cortex, right lung, right lung lobe, right ovary, seminal vesicula, stromal cell of endometrium, thymus, tunica media of zone of aorta, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fas receptor

Top relations

Gene ontology · 76
Fas receptor → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, activation-induced cell death of T cells, apoptotic process, apoptotic signaling pathway, B cell mediated immunity, calmodulin binding, CD95 death-inducing signaling complex, cell surface, cellular response to amino acid starvation, cellular response to hyperoxia, cellular response to lithium ion, cellular response to mechanical stimulus, circadian rhythm, cytosol, death-inducing signaling complex, external side of plasma membrane, extracellular exosome, extracellular region, extrinsic apoptotic signaling pathway
Bgee · 20
Fas receptor → brown adipose tissue, duodenum, epithelium of nasopharynx, gallbladder, granulocyte, intercostal muscle, jejunum, left adrenal cortex, left adrenal gland, left ovary, rectum, right adrenal cortex, right lung, right lung lobe, right ovary, seminal vesicula, stromal cell of endometrium, thymus, tunica media of zone of aorta, white adipose tissue
RNA expression pattern · 20
Fas receptor → brown adipose tissue, duodenum, epithelium of nasopharynx, gallbladder, granulocyte, intercostal muscle, jejunum, left adrenal cortex, left adrenal gland, left ovary, rectum, right adrenal cortex, right lung, right lung lobe, right ovary, seminal vesicula, stromal cell of endometrium, thymus, tunica media of zone of aorta, white adipose tissue
related to Protein · 10
Fas receptor → Apoptosis-inducing Fas, Exon, Exons, Fas, However, Many, Previous, RNA, The, TIA1
related to Interactions · 5
Fas receptor → Caspase, CFLAR, FADD, Fas, PDCD6
related to Gene · 4
Fas receptor → FAS, Similar, The, Watson
Band · 2
Fas receptor → 10q23.31, 19 C1|19 29.48 cM
Chr. · 2
Fas receptor → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
Fas receptor → 34,327,772 bp, 89,029,605 bp
Aliases · 1
Fas receptor → FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fas apoptosis receptor cell protein tumor cells gene human death bp 10 surface ligand chr band chromosome mouse domain also

Fas receptor relationships Subject–Predicate–Object triples

TTTA extracted 162 structured relationships around Fas receptor. Examples in this analysis include Fas receptor → Aliases → FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor and Fas receptor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DDF, 3EWT, 3EZQ, 3THM, 3TJE, 2NA7. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fas receptorAliasesFAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor1.00infobox
Fas receptorAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DDF, 3EWT, 3EZQ, 3THM, 3TJE, 2NA71.00infobox
Fas receptorBand10q23.311.00infobox
Fas receptorBand19 C1|19 29.48 cM1.00infobox
Fas receptorBgeerectum1.00infobox
Fas receptorBgeeleft ovary1.00infobox
Fas receptorBgeeright ovary1.00infobox
Fas receptorBgeegallbladder1.00infobox
Fas receptorBgeeepithelium of nasopharynx1.00infobox
Fas receptorBgeeright lung1.00infobox
Fas receptorBgeeleft adrenal gland1.00infobox
Fas receptorBgeestromal cell of endometrium1.00infobox
Fas receptorBgeeright adrenal cortex1.00infobox
Fas receptorBgeeleft adrenal cortex1.00infobox
Fas receptorBgeegranulocyte1.00infobox
Fas receptorBgeethymus1.00infobox
Fas receptorBgeeright lung lobe1.00infobox
Fas receptorBgeetunica media of zone of aorta1.00infobox
Fas receptorBgeeseminal vesicula1.00infobox
Fas receptorBgeeintercostal muscle1.00infobox
Fas receptorBgeeduodenum1.00infobox
Fas receptorBgeejejunum1.00infobox
Fas receptorBgeebrown adipose tissue1.00infobox
Fas receptorBgeewhite adipose tissue1.00infobox
Fas receptorBioGPSMore reference expression data1.00infobox
Fas receptorChr.Chromosome 10 (human)1.00infobox
Fas receptorChr.Chromosome 19 (mouse)1.00infobox
Fas receptorDatabasesNCBI: entry; OMA: entry1.00infobox
Fas receptorEnd89,029,605 bp1.00infobox
Fas receptorEnd34,327,772 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fas receptor bring nearby vocabulary together. In this analysis, examples include Cell, Necrosis and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fas receptor
    • Cell
    • Necrosis
    • Receptor
    • Apoptosis
    • Pdb
    • Uniprot
    • Ligand
    • Cells
    • Protein
    • Tumor
    • Surface
    • Death
  • fas receptor
    • Cell
    • Necrosis
    • Receptor
    • Apoptosis
    • Death
    • Pdb
    • Uniprot
    • Protein
    • Tumor
    • Ligand
    • Gene
    • Surface
  • tumor necrosis factor receptor superfamily
    • Necrosis
    • Uniprot
    • Tumor
    • Pdb
    • Receptor
    • Shown
    • Gene
    • Mouse
    • Death
    • Human
    • Protein
    • Cell
  • protein
    • Gene
    • Transmembrane
    • Receptor
    • External
    • Function
    • Location
    • Cell
    • Chromosome
    • Extracellular
    • Amino
    • Binding
    • Bp
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • External
    • Protein
    • Human
    • Function
    • Band
    • Necrosis
    • Mouse
    • Surface
  • death receptor
    • Domain
    • Function
    • Necrosis
    • Surface
    • External
    • Death
    • Receptor
    • Location
    • Pdb
    • Uniprot
    • Protein
    • Tumor
  • fas ligand
    • Surface
    • Cell
    • Receptor
    • Apoptosis
    • Region
    • Ligand
    • Binding
    • Citation
    • Needed
    • Cells
    • Protein
    • Tumor
  • chromosome 10
    • Bp
    • Location
    • Human
    • Band
    • External
    • Gene
    • Function
    • Mouse
    • Surface
    • Death
    • Protein
    • Pathway

Connections between topic areas Semantic bridges

For Fas receptor, one of the stronger structural bridges in this analysis connects Fas receptor with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Fas receptorFunction · splits 40 ⟂ 14
Fas receptorOverview · splits 45 ⟂ 9
Fas receptorProtein · splits 45 ⟂ 9
Fas receptorRole in apoptosis · splits 45 ⟂ 9
Fas receptorGene · splits 48 ⟂ 6
Fas receptorInteractions · splits 48 ⟂ 6

Map overview Semantic statistics

Fas receptor

Nodes54
Edges53
Triples162
Avg. degree1.96
Density0.037037
Components1

Source & methodology

TTTA analyzes the structure around Fas receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Protein, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fas receptor · EN edition · Analysis: TopicsToTalkAbout

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