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Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene.
The analysis highlights Function, Clinical significance in cancer and Structure as prominent areas in the source structure around MBD4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MBD4 shows recurring relationship patterns in the source. For example, MBD4 → caput epididymis, cardia, corpus epididymis, ejaculatory duct, embryo, epiblast, epithelium of male urethra, epithelium of nasopharynx, genital tubercle, lumbar spinal ganglion, optic nerve, pelvic part of vagina, pylorus, renal medulla, Rostral migratory stream, secondary oocyte, tail of embryo, trabecular bone, vagina, visceral pleura Another extracted example is MBD4 → catalytic activity, cellular response to DNA damage stimulus, chromatin, depyrimidination, DNA binding, DNA N-glycosylase activity, DNA repair, endodeoxyribonuclease activity, hydrolase activity, nuclear speck, nucleoplasm, nucleus, protein binding, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, response to estradiol, response to radiation, satellite DNA binding. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
mutations dna human gene deamination bp protein chr band repair cpg cancers chromosome domain mlh1 function colorectal cancer expression base
TTTA extracted 141 structured relationships around MBD4. Examples in this analysis include MBD4 → Aliases → MBD4, MED1, methyl-CpG binding domain 4, DNA glycosylase and MBD4 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2MOE, 3IHO, 4DK9, 4E9E, 4E9F, 4E9G, 4E9H, 4EA4, 4EA5, 4LG7, 4OFA, 4OFE, 4OFH, 5CHZ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MBD4 | Aliases | MBD4, MED1, methyl-CpG binding domain 4, DNA glycosylase | 1.00 | infobox |
| MBD4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2MOE, 3IHO, 4DK9, 4E9E, 4E9F, 4E9G, 4E9H, 4EA4, 4EA5, 4LG7, 4OFA, 4OFE, 4OFH, 5CHZ | 1.00 | infobox |
| MBD4 | Band | 3q21.3 | 1.00 | infobox |
| MBD4 | Band | 6 E3|6 53.72 cM | 1.00 | infobox |
| MBD4 | Bgee | secondary oocyte | 1.00 | infobox |
| MBD4 | Bgee | pylorus | 1.00 | infobox |
| MBD4 | Bgee | visceral pleura | 1.00 | infobox |
| MBD4 | Bgee | trabecular bone | 1.00 | infobox |
| MBD4 | Bgee | caput epididymis | 1.00 | infobox |
| MBD4 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| MBD4 | Bgee | optic nerve | 1.00 | infobox |
| MBD4 | Bgee | cardia | 1.00 | infobox |
| MBD4 | Bgee | renal medulla | 1.00 | infobox |
| MBD4 | Bgee | corpus epididymis | 1.00 | infobox |
| MBD4 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| MBD4 | Bgee | epithelium of male urethra | 1.00 | infobox |
| MBD4 | Bgee | genital tubercle | 1.00 | infobox |
| MBD4 | Bgee | tail of embryo | 1.00 | infobox |
| MBD4 | Bgee | vagina | 1.00 | infobox |
| MBD4 | Bgee | Rostral migratory stream | 1.00 | infobox |
| MBD4 | Bgee | ejaculatory duct | 1.00 | infobox |
| MBD4 | Bgee | pelvic part of vagina | 1.00 | infobox |
| MBD4 | Bgee | epiblast | 1.00 | infobox |
| MBD4 | Bgee | embryo | 1.00 | infobox |
| MBD4 | BioGPS | More reference expression data | 1.00 | infobox |
| MBD4 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| MBD4 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| MBD4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MBD4 | End | 129,440,179 bp | 1.00 | infobox |
| MBD4 | End | 115,830,332 bp | 1.00 | infobox |
The concept neighborhoods around MBD4 bring nearby vocabulary together. In this analysis, examples include Protein, Repair and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MBD4, one of the stronger structural bridges in this analysis connects MBD4 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MBD4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance in cancer & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MBD4 · EN edition · Analysis: TopicsToTalkAbout