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DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the DFFA gene.
The analysis highlights Measurement, Overview and Interactions as prominent areas in the source structure around DFFA.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around DFFA shows recurring relationship patterns in the source. For example, DFFA → cardia, cartilage tissue, inferior ganglion of vagus nerve, internal globus pallidus, islet of Langerhans, lip, medulla oblongata, muscle of thigh, nipple, pons, primary motor cortex, quadriceps femoris muscle, renal medulla, soleus muscle, stromal cell of endometrium, subthalamic nucleus, tibialis anterior muscle, ventral tegmental area, yolk sac, zone of skin Another extracted example is DFFA → apoptotic DNA fragmentation, apoptotic process, chaperone-mediated protein folding, cytoplasm, cytosol, deoxyribonuclease inhibitor activity, intracellular anatomical structure, lipid droplet, negative regulation of apoptotic DNA fragmentation, negative regulation of deoxyribonuclease activity, negative regulation of execution phase of apoptosis, nucleoplasm, nucleus, plasma membrane, positive regulation of apoptotic process, protein binding, protein domain specific binding, protein folding chaperone activity, thymocyte apoptotic process. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna fragmentation dffb gene bp chr apoptosis process human band c-terminal protein apoptotic domain chromosome dff factor dnase location also
TTTA extracted 84 structured relationships around DFFA. Examples in this analysis include DFFA → Aliases → DFFA, DFF-45, DFF1, ICAD, DNA fragmentation factor subunit alpha and DFFA → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IBX, 1IYR, 1KOY. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DFFA | Aliases | DFFA, DFF-45, DFF1, ICAD, DNA fragmentation factor subunit alpha | 1.00 | infobox |
| DFFA | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IBX, 1IYR, 1KOY | 1.00 | infobox |
| DFFA | Band | 1p36.22 | 1.00 | infobox |
| DFFA | Band | 4|4 E2 | 1.00 | infobox |
| DFFA | Bgee | internal globus pallidus | 1.00 | infobox |
| DFFA | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| DFFA | Bgee | nipple | 1.00 | infobox |
| DFFA | Bgee | cardia | 1.00 | infobox |
| DFFA | Bgee | ventral tegmental area | 1.00 | infobox |
| DFFA | Bgee | cartilage tissue | 1.00 | infobox |
| DFFA | Bgee | stromal cell of endometrium | 1.00 | infobox |
| DFFA | Bgee | renal medulla | 1.00 | infobox |
| DFFA | Bgee | subthalamic nucleus | 1.00 | infobox |
| DFFA | Bgee | islet of Langerhans | 1.00 | infobox |
| DFFA | Bgee | soleus muscle | 1.00 | infobox |
| DFFA | Bgee | yolk sac | 1.00 | infobox |
| DFFA | Bgee | medulla oblongata | 1.00 | infobox |
| DFFA | Bgee | lip | 1.00 | infobox |
| DFFA | Bgee | pons | 1.00 | infobox |
| DFFA | Bgee | quadriceps femoris muscle | 1.00 | infobox |
| DFFA | Bgee | zone of skin | 1.00 | infobox |
| DFFA | Bgee | muscle of thigh | 1.00 | infobox |
| DFFA | Bgee | primary motor cortex | 1.00 | infobox |
| DFFA | Bgee | tibialis anterior muscle | 1.00 | infobox |
| DFFA | BioGPS | More reference expression data | 1.00 | infobox |
| DFFA | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| DFFA | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| DFFA | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| DFFA | End | 10,472,529 bp | 1.00 | infobox |
| DFFA | End | 149,205,104 bp | 1.00 | infobox |
The concept neighborhoods around DFFA bring nearby vocabulary together. In this analysis, examples include Dna, Fragmentation and Dffb. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For DFFA, one of the stronger structural bridges in this analysis connects DFFA with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around DFFA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Overview & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — DFFA · EN edition · Analysis: TopicsToTalkAbout