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PEA15: Interactions & Overview

Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene.

Language: English [EN]
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PEA15 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around PEA15.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
81
Concept neighborhoods
6
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Overview · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PEA15, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, phosphoprotein enriched in astrocytes 15, PED-PED/proliferation and apoptosis adaptor protein 15
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IZ5, 4IZA, 1N3K,%%s1N3K
Band
1q23.2 · 1 H3|1 79.54 cM
Bgee
dorsal motor nucleus of vagus nerve · spinal cord · C1 segment · subthalamic nucleus · inferior ganglion of vagus nerve
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PEA15 connects Entity context

The extracted context around PEA15 shows recurring relationship patterns in the source. For example, PEA15 → arcuate nucleus, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsal motor nucleus of vagus nerve, external globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, median eminence, neural layer of retina, optic nerve, pars reticulata, spinal cord, subiculum, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area, ventricular zone, ventromedial nucleus Another extracted example is PEA15 → apoptotic process, carbohydrate transport, cytoplasm, cytosol, DNA damage checkpoint signaling, MAPK cascade, microtubule associated complex, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of glucose import, nucleus, positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, protein binding, regulation of apoptotic process, response to morphine. Use these groups to spot repeated connection types before inspecting the individual relationships.

PEA15

Top relations

Bgee · 20
PEA15 → arcuate nucleus, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsal motor nucleus of vagus nerve, external globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, median eminence, neural layer of retina, optic nerve, pars reticulata, spinal cord, subiculum, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area, ventricular zone, ventromedial nucleus
RNA expression pattern · 20
PEA15 → arcuate nucleus, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsal motor nucleus of vagus nerve, external globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, median eminence, neural layer of retina, optic nerve, pars reticulata, spinal cord, subiculum, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area, ventricular zone, ventromedial nucleus
Gene ontology · 14
PEA15 → apoptotic process, carbohydrate transport, cytoplasm, cytosol, DNA damage checkpoint signaling, MAPK cascade, microtubule associated complex, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of glucose import, nucleus, positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, protein binding, regulation of apoptotic process, response to morphine
related to Interactions · 3
PEA15 → Caspase, FADD, Phospholipase D1
Band · 2
PEA15 → 1 H3|1 79.54 cM, 1q23.2
Chr. · 2
PEA15 → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
PEA15 → 160,215,376 bp, 172,034,371 bp
Aliases · 1
PEA15 → PEA15, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, phosphoprotein enriched in astrocytes 15, PED-PED/proliferation and apoptosis adaptor protein 15
Available structures · 1
PEA15 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IZ5, 4IZA, 1N3K,%%s1N3K
BioGPS · 1
PEA15 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp protein chr human band gene chromosome pea-15 location astrocytes mouse phosphoprotein death domain expressed external search 215 376 end

PEA15 relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around PEA15. Examples in this analysis include PEA15 → Aliases → PEA15, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, phosphoprotein enriched in astrocytes 15, PED-PED/proliferation and apoptosis adaptor protein 15 and PEA15 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IZ5, 4IZA, 1N3K,%%s1N3K. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PEA15AliasesPEA15, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, phosphoprotein enriched in astrocytes 15, PED-PED/proliferation and apoptosis adaptor protein 151.00infobox
PEA15Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IZ5, 4IZA, 1N3K,%%s1N3K1.00infobox
PEA15Band1q23.21.00infobox
PEA15Band1 H3|1 79.54 cM1.00infobox
PEA15Bgeedorsal motor nucleus of vagus nerve1.00infobox
PEA15Bgeespinal cord1.00infobox
PEA15BgeeC1 segment1.00infobox
PEA15Bgeesubthalamic nucleus1.00infobox
PEA15Bgeeinferior ganglion of vagus nerve1.00infobox
PEA15Bgeeinternal globus pallidus1.00infobox
PEA15Bgeesuperior vestibular nucleus1.00infobox
PEA15Bgeeexternal globus pallidus1.00infobox
PEA15Bgeeinferior olivary nucleus1.00infobox
PEA15Bgeepars reticulata1.00infobox
PEA15Bgeeventricular zone1.00infobox
PEA15Bgeeneural layer of retina1.00infobox
PEA15Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PEA15Bgeesubiculum1.00infobox
PEA15Bgeeoptic nerve1.00infobox
PEA15Bgeecerebellar cortex1.00infobox
PEA15Bgeearcuate nucleus1.00infobox
PEA15Bgeeventromedial nucleus1.00infobox
PEA15Bgeeventral tegmental area1.00infobox
PEA15Bgeemedian eminence1.00infobox
PEA15BioGPSMore reference expression data1.00infobox
PEA15Chr.Chromosome 1 (human)1.00infobox
PEA15Chr.Chromosome 1 (mouse)1.00infobox
PEA15DatabasesNCBI: entry; OMA: entry1.00infobox
PEA15End160,215,376 bp1.00infobox
PEA15End172,034,371 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PEA15 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Astrocytes. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PEA15
    • Protein
    • Gene
    • Astrocytes
    • Death
    • Domain
    • Expressed
    • External
    • Phosphoprotein
    • Search
    • Location
    • Chromosome
    • Human
  • pea15
    • Protein
    • Gene
    • Astrocytes
    • Death
    • Domain
    • Expressed
    • External
    • Phosphoprotein
    • Search
    • Location
    • Chromosome
    • Human
  • astrocytes
    • Central
    • Ded
    • Effector
    • Nervous
    • Particularly
    • Pea15
    • Predominantly
    • Protein
    • System
    • Death
    • Domain
    • Expressed
  • gene
    • Location
    • Chromosome
    • Human
    • Pea15
    • Protein
    • Bp
    • Chr
    • End
    • External
    • H3
    • Mouse
    • Phosphoprotein
  • central nervous system
    • -containing
    • Central
    • Ded
    • Effector
    • Nervous
    • Particularly
    • Predominantly
    • System
    • Astrocytes
    • Death
    • Domain
    • Expressed
  • protein
    • External
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • System
    • End
    • H3
    • Mouse
    • Band

Connections between topic areas Semantic bridges

For PEA15, one of the stronger structural bridges in this analysis connects PEA15 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PEA15Interactions · splits 6 ⟂ 7
PEA15Overview · splits 8 ⟂ 5

Map overview Semantic statistics

PEA15

Nodes13
Edges12
Triples81
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around PEA15 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PEA15 · EN edition · Analysis: TopicsToTalkAbout

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