TRADD

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Function

Death domain TNFRSF1A TNFR1 Programmed cell death NF-κB

8 related topics

Interactions

Interact Keratin 18 RIPK1 STAT1 TNFRSF25

5 related topics

Overview

Protein Gene Adaptor protein

3 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TRADD, Hs.89862, TNFRSF1A associated via death domain
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2H, 1F3V
Band: 16q22.1 · 8 D3|8 53.04 cM
Bgee: pancreatic ductal cell · granulocyte · right uterine tube · mucosa of transverse colon · amniotic fluid
BioGPS: More reference expression data
Chr.: Chromosome 16 (human) · Chromosome 8 (mouse)

Topics to explore

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Overview

Protein
Gene
Adaptor protein Signal transducing adaptor protein

Function

Interactions

Interact Protein-protein interaction
Keratin 18
RIPK1
STAT1
TNFRSF25

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes20

Edges19

Triples109

Avg. degree1.9

Density0.1

Components1

How this topic connects Entity context

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TRADD

Top relations

Gene ontology · 38

TRADD → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to tumor necrosis factor, cytoplasm, cytoskeleton, cytosol, death domain binding, death-inducing signaling complex, death-inducing signaling complex assembly, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, I-kappaB kinase/NF-kappaB signaling, identical protein binding, kinase binding, membrane raft, molecular adaptor activity, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, nucleus, plasma membrane, positive regulation of apoptotic process

Bgee · 19

TRADD → amniotic fluid, blood, duodenum, epithelium of nasopharynx, epithelium of stomach, extensor digitorum longus muscle, gingival epithelium, granulocyte, Ileal epithelium, intestinal villus, jejunum, left colon, lumbar spinal ganglion, mucosa of transverse colon, palpebral conjunctiva, pancreatic ductal cell, parotid gland, plantaris muscle, right uterine tube

RNA expression pattern · 19

related to Interactions · 5

TRADD → FADD, Keratin, STAT1, TNFRSF1A, TNFRSF25

related to External links · 4

TRADD → Medicine Medical Subject Headings, MeSH, National Library, Protein

Band · 2

TRADD → 16q22.1, 8 D3|8 53.04 cM

Chr. · 2

TRADD → Chromosome 16 (human), Chromosome 8 (mouse)

End · 2

TRADD → 105,991,241 bp, 67,159,909 bp

Aliases · 1

TRADD → TRADD, Hs.89862, TNFRSF1A associated via death domain

Available structures · 1

TRADD → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2H, 1F3V

Important terminology Word statistics

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Important terminology

protein bp gene chr human band death adaptor domain chromosome 16 receptor location tnfrsf1a mouse cell tumor necrosis factor function

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
TRADD	Aliases	TRADD, Hs.89862, TNFRSF1A associated via death domain	1.00	infobox
TRADD	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2H, 1F3V	1.00	infobox
TRADD	Band	16q22.1	1.00	infobox
TRADD	Band	8 D3\|8 53.04 cM	1.00	infobox
TRADD	Bgee	pancreatic ductal cell	1.00	infobox
TRADD	Bgee	granulocyte	1.00	infobox
TRADD	Bgee	right uterine tube	1.00	infobox
TRADD	Bgee	mucosa of transverse colon	1.00	infobox
TRADD	Bgee	amniotic fluid	1.00	infobox
TRADD	Bgee	parotid gland	1.00	infobox
TRADD	Bgee	blood	1.00	infobox
TRADD	Bgee	palpebral conjunctiva	1.00	infobox
TRADD	Bgee	epithelium of nasopharynx	1.00	infobox
TRADD	Bgee	gingival epithelium	1.00	infobox
TRADD	Bgee	intestinal villus	1.00	infobox
TRADD	Bgee	left colon	1.00	infobox
TRADD	Bgee	Ileal epithelium	1.00	infobox
TRADD	Bgee	lumbar spinal ganglion	1.00	infobox
TRADD	Bgee	jejunum	1.00	infobox
TRADD	Bgee	plantaris muscle	1.00	infobox
TRADD	Bgee	extensor digitorum longus muscle	1.00	infobox
TRADD	Bgee	duodenum	1.00	infobox
TRADD	Bgee	epithelium of stomach	1.00	infobox
TRADD	BioGPS	More reference expression data	1.00	infobox
TRADD	Chr.	Chromosome 16 (human)	1.00	infobox
TRADD	Chr.	Chromosome 8 (mouse)	1.00	infobox
TRADD	Databases	NCBI: entry; OMA: entry	1.00	infobox
TRADD	End	67,159,909 bp	1.00	infobox
TRADD	End	105,991,241 bp	1.00	infobox
TRADD	Ensembl	ENSG00000102871	1.00	infobox

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