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IRF7: Function, Interactions & Overview

Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors.

Language: English [EN]
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IRF7 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around IRF7.

Related topics
11
Source areas
3
Connected nodes
14
Extracted relationships
128
Concept neighborhoods
10
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O61
Band
11p15.5 · 7|7 F5
Bgee
granulocyte · blood · right lobe of liver · spleen · monocyte
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 7 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IRF7 connects Entity context

The extracted context around IRF7 shows recurring relationship patterns in the source. For example, IRF7 → cellular response to DNA damage stimulus, cis-regulatory region sequence-specific DNA binding, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endosome membrane, establishment of viral latency, immune system process, immunoglobulin mediated immune response, innate immune response, interferon-alpha production, interferon-beta production, interferon-gamma-mediated signaling pathway, MDA-5 signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of transcription by RNA polymerase II, nucleoplasm Another extracted example is IRF7 → apex of heart, blood, bone marrow, bone marrow cell, colon, duodenum, gastrula, granulocyte, ileum, jejunum, large intestine, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, right lobe of liver, spleen, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.

IRF7

Top relations

Gene ontology · 45
IRF7 → cellular response to DNA damage stimulus, cis-regulatory region sequence-specific DNA binding, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endosome membrane, establishment of viral latency, immune system process, immunoglobulin mediated immune response, innate immune response, interferon-alpha production, interferon-beta production, interferon-gamma-mediated signaling pathway, MDA-5 signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of transcription by RNA polymerase II, nucleoplasm
Bgee · 18
IRF7 → apex of heart, blood, bone marrow, bone marrow cell, colon, duodenum, gastrula, granulocyte, ileum, jejunum, large intestine, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, right lobe of liver, spleen, thymus
RNA expression pattern · 18
IRF7 → apex of heart, blood, bone marrow, bone marrow cell, colon, duodenum, gastrula, granulocyte, ileum, jejunum, large intestine, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, right lobe of liver, spleen, thymus
related to External links · 10
IRF7 → Interferon, Media, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library, Wikimedia CommonsIRF7, Wiktionary-logo-en-v2
related to Function · 6
IRF7 → Constitutive, In, IRF, Multiple IRF7, Restoring IRF7, The IRF7
related to Interactions · 5
IRF7 → AIP, Also, Aryl Hydrocarbon Receptor Interacting, IRF3, Protein
Band · 2
IRF7 → 11p15.5, 7|7 F5
Chr. · 2
IRF7 → Chromosome 11 (human), Chromosome 7 (mouse)
End · 2
IRF7 → 140,846,394 bp, 615,983 bp
Aliases · 1
IRF7 → IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human interferon chr band factor chromosome 11 regulatory gene shown also transcription location mouse cell protein pathway function external

IRF7 relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around IRF7. Examples in this analysis include IRF7 → Aliases → IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7 and IRF7 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O61. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IRF7AliasesIRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-71.00infobox
IRF7Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O611.00infobox
IRF7Band11p15.51.00infobox
IRF7Band7|7 F51.00infobox
IRF7Bgeegranulocyte1.00infobox
IRF7Bgeeblood1.00infobox
IRF7Bgeeright lobe of liver1.00infobox
IRF7Bgeespleen1.00infobox
IRF7Bgeemonocyte1.00infobox
IRF7Bgeemucosa of transverse colon1.00infobox
IRF7Bgeeapex of heart1.00infobox
IRF7Bgeelymph node1.00infobox
IRF7Bgeebone marrow1.00infobox
IRF7Bgeebone marrow cell1.00infobox
IRF7Bgeegastrula1.00infobox
IRF7Bgeemucous cell of stomach1.00infobox
IRF7Bgeeileum1.00infobox
IRF7Bgeejejunum1.00infobox
IRF7Bgeeduodenum1.00infobox
IRF7Bgeelarge intestine1.00infobox
IRF7Bgeecolon1.00infobox
IRF7Bgeethymus1.00infobox
IRF7BioGPSMore reference expression data1.00infobox
IRF7Chr.Chromosome 11 (human)1.00infobox
IRF7Chr.Chromosome 7 (mouse)1.00infobox
IRF7DatabasesNCBI: entry; OMA: entry1.00infobox
IRF7End615,983 bp1.00infobox
IRF7End140,846,394 bp1.00infobox
IRF7EnsemblENSG00000276561 ENSG000001855071.00infobox
IRF7Entrez36651.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IRF7 bring nearby vocabulary together. In this analysis, examples include Shown, Regulatory and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IRF7
    • Shown
    • Regulatory
    • Cell
    • Pathway
    • Protein
    • Gene
    • Human
    • Cellular
    • Expression
    • Function
    • Genes
    • Immune
  • irf7
    • Shown
    • Regulatory
    • Cell
    • Pathway
    • Protein
    • Gene
    • Human
    • Cellular
    • Expression
    • Function
    • Genes
    • Immune
  • interferon regulatory factor
    • Regulatory
    • Family
    • Function
    • Member
    • Search
    • Transcription
    • Factor
    • Interferon
    • Also
    • Human
    • Location
    • Cellular
  • virus-inducible cellular genes
    • Type
    • Interferon
    • End
    • Expression
    • Family
    • Function
    • Genes
    • Immune
    • Interferon-alpha
    • Member
    • Mouse
    • Negative
  • type i interferon
    • Regulatory
    • Factor
    • Human
    • Cellular
    • Factors
    • Family
    • Function
    • Member
    • Search
    • Transcription
    • Type
    • Irf7
  • function
    • Search
    • Location
    • Chromosome
    • Gene
    • Regulatory
    • Bp
    • Chr
    • Human
    • Interferon
    • Cellular
    • End
    • Expression
  • interferon-alpha
    • Genes
    • Immune
    • Member
    • Mouse
    • Negative
    • Receptor
    • Response
    • Search
    • Transcription
    • Type
    • Viral
    • Location
  • transcription factors
    • Regulatory
    • Interferon
    • Family
    • Member
    • Negative
    • Receptor
    • Response
    • Search
    • Transcription
    • Type
    • Viral
    • Pathway

Connections between topic areas Semantic bridges

For IRF7, one of the stronger structural bridges in this analysis connects IRF7 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IRF7Function · splits 8 ⟂ 7
IRF7Interactions · splits 11 ⟂ 4
IRF7Overview · splits 12 ⟂ 3

Map overview Semantic statistics

IRF7

Nodes15
Edges14
Triples128
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around IRF7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IRF7 · EN edition · Analysis: TopicsToTalkAbout

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