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Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around IRF7.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around IRF7 shows recurring relationship patterns in the source. For example, IRF7 → cellular response to DNA damage stimulus, cis-regulatory region sequence-specific DNA binding, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endosome membrane, establishment of viral latency, immune system process, immunoglobulin mediated immune response, innate immune response, interferon-alpha production, interferon-beta production, interferon-gamma-mediated signaling pathway, MDA-5 signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of transcription by RNA polymerase II, nucleoplasm Another extracted example is IRF7 → apex of heart, blood, bone marrow, bone marrow cell, colon, duodenum, gastrula, granulocyte, ileum, jejunum, large intestine, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, right lobe of liver, spleen, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp human interferon chr band factor chromosome 11 regulatory gene shown also transcription location mouse cell protein pathway function external
TTTA extracted 117 structured relationships around IRF7. Examples in this analysis include IRF7 → Aliases → IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7 and IRF7 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O61. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRF7 | Aliases | IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7 | 1.00 | infobox |
| IRF7 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O61 | 1.00 | infobox |
| IRF7 | Band | 11p15.5 | 1.00 | infobox |
| IRF7 | Band | 7|7 F5 | 1.00 | infobox |
| IRF7 | Bgee | granulocyte | 1.00 | infobox |
| IRF7 | Bgee | blood | 1.00 | infobox |
| IRF7 | Bgee | right lobe of liver | 1.00 | infobox |
| IRF7 | Bgee | spleen | 1.00 | infobox |
| IRF7 | Bgee | monocyte | 1.00 | infobox |
| IRF7 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| IRF7 | Bgee | apex of heart | 1.00 | infobox |
| IRF7 | Bgee | lymph node | 1.00 | infobox |
| IRF7 | Bgee | bone marrow | 1.00 | infobox |
| IRF7 | Bgee | bone marrow cell | 1.00 | infobox |
| IRF7 | Bgee | gastrula | 1.00 | infobox |
| IRF7 | Bgee | mucous cell of stomach | 1.00 | infobox |
| IRF7 | Bgee | ileum | 1.00 | infobox |
| IRF7 | Bgee | jejunum | 1.00 | infobox |
| IRF7 | Bgee | duodenum | 1.00 | infobox |
| IRF7 | Bgee | large intestine | 1.00 | infobox |
| IRF7 | Bgee | colon | 1.00 | infobox |
| IRF7 | Bgee | thymus | 1.00 | infobox |
| IRF7 | BioGPS | More reference expression data | 1.00 | infobox |
| IRF7 | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| IRF7 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| IRF7 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRF7 | End | 615,983 bp | 1.00 | infobox |
| IRF7 | End | 140,846,394 bp | 1.00 | infobox |
| IRF7 | Ensembl | ENSG00000276561 ENSG00000185507 | 1.00 | infobox |
| IRF7 | Entrez | 3665 | 1.00 | infobox |
The concept neighborhoods around IRF7 bring nearby vocabulary together. In this analysis, examples include Shown, Regulatory and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IRF7, one of the stronger structural bridges in this analysis connects IRF7 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IRF7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IRF7 · EN edition · Analysis: TopicsToTalkAbout
