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Tuberous sclerosis complex 2 (TSC2), also known as tuberin, is a protein that in humans is encoded by the TSC2 gene.
The analysis highlights Interactions, Function and Cell pathology as prominent areas in the source structure around TSC2. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TSC2 shows recurring relationship patterns in the source. For example, TSC2 → anoikis, cytoplasm, cytosol, development of the heart, endocytosis, Golgi apparatus, GTPase activator activity, Hsp90 protein binding, insulin-like growth factor receptor signaling pathway, lysosome, membrane, negative regulation of cell population proliferation, negative regulation of insulin receptor signaling pathway, negative regulation of mitophagy, negative regulation of phosphatidylinositol 3-kinase signaling, negative regulation of protein kinase activity, negative regulation of protein kinase B signaling, negative regulation of TOR signaling, negative regulation of Wnt signaling pathway, neural tube closure Another extracted example is TSC2 → anterior pituitary, CA3 field, cardiac muscle tissue of left ventricle, dentate gyrus of hippocampal formation granule cell, genital tubercle, left lobe of thyroid gland, left ovary, left testis, muscle of thigh, neural layer of retina, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right testis, right uterine tube, superior frontal gyrus, sural nerve, tail of embryo, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp complex protein chr human band tuberous sclerosis chromosome 16 location cell hsp90 mutations tuberin tsc1 also mouse tsc
TTTA extracted 115 structured relationships around TSC2. Examples in this analysis include TSC2 → Aliases → TSC2, LAM, PPP1R160, TSC4, tuberous sclerosis 2, TSC complex subunit 2 and TSC2 → Band → 16p13.3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TSC2 | Aliases | TSC2, LAM, PPP1R160, TSC4, tuberous sclerosis 2, TSC complex subunit 2 | 1.00 | infobox |
| TSC2 | Band | 16p13.3 | 1.00 | infobox |
| TSC2 | Band | 17 A3.3|17 12.41 cM | 1.00 | infobox |
| TSC2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| TSC2 | Bgee | anterior pituitary | 1.00 | infobox |
| TSC2 | Bgee | right uterine tube | 1.00 | infobox |
| TSC2 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| TSC2 | Bgee | sural nerve | 1.00 | infobox |
| TSC2 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| TSC2 | Bgee | right testis | 1.00 | infobox |
| TSC2 | Bgee | left testis | 1.00 | infobox |
| TSC2 | Bgee | right frontal lobe | 1.00 | infobox |
| TSC2 | Bgee | left ovary | 1.00 | infobox |
| TSC2 | Bgee | tail of embryo | 1.00 | infobox |
| TSC2 | Bgee | genital tubercle | 1.00 | infobox |
| TSC2 | Bgee | superior frontal gyrus | 1.00 | infobox |
| TSC2 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| TSC2 | Bgee | primary visual cortex | 1.00 | infobox |
| TSC2 | Bgee | neural layer of retina | 1.00 | infobox |
| TSC2 | Bgee | muscle of thigh | 1.00 | infobox |
| TSC2 | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| TSC2 | Bgee | ventricular zone | 1.00 | infobox |
| TSC2 | Bgee | CA3 field | 1.00 | infobox |
| TSC2 | BioGPS | More reference expression data | 1.00 | infobox |
| TSC2 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| TSC2 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| TSC2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TSC2 | End | 2,089,491 bp | 1.00 | infobox |
| TSC2 | End | 24,851,604 bp | 1.00 | infobox |
| TSC2 | Ensembl | ENSG00000103197 | 1.00 | infobox |
The concept neighborhoods around TSC2 bring nearby vocabulary together. In this analysis, examples include Mutations, Cell and Tsc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TSC2, one of the stronger structural bridges in this analysis connects TSC2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TSC2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Cell pathology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TSC2 · EN edition · Analysis: TopicsToTalkAbout