PRKCQ

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Function

Protein kinase C Protein kinases Second messenger Diacylglycerol Phorbol esters

32 related topics

Interactions

Interact AKT1 FYN GLRX3 VAV1

5 related topics

Overview

Enzyme Gene Hematopoietic cells Platelets T lymphocytes

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.13: ↗
Aliases: PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XJD, 2ENJ, 2ENN, 2ENZ, 2JED, 4Q9Z, 4RA5, 5F9E
Band: 10p15.1 · 2 A1|2 8.42 cM
Bgee: triceps brachii muscle · glutes · biceps brachii · vastus lateralis muscle · Skeletal muscle tissue of biceps brachii
BioGPS: More reference expression data

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Protein kinase C
Protein kinases Protein kinase
Second messenger
Diacylglycerol
Phorbol esters Phorbol ester
Phospholipid
T-cell
NF-kappaB
AP-1 AP-1 transcription factor
T cell receptor
Transcription factors Transcription factor
Apoptosis
Lymphoid cells
Spectrin
CD28
Antigen presenting cell Antigen-presenting cell
MHC Major histocompatibility complex
LFA-1 Lymphocyte function-associated antigen 1
ICAM-1
SUMO1 Small ubiquitin-related modifier 1
Carma-1 CARD11
Bcl-10 BCL10
Malt-1 MALT1
Th2
Th17 T helper 17 cell
NK cells Natural killer cell
MHCI MHC class I
NF-κB
NF-AT
IL-2 Interleukin 2

Interactions

Interact Protein-protein interaction
AKT1
FYN
GLRX3
VAV1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes46

Edges45

Triples110

Avg. degree1.96

Density0.043478

Components1

How this topic connects Entity context

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PRKCQ

Top relations

Gene ontology · 45

PRKCQ → aggresome, ATP binding, axon guidance, cell chemotaxis, cytoplasm, cytosol, Fc-epsilon receptor signaling pathway, immune system process, immunological synapse, inflammatory response, intracellular anatomical structure, intracellular signal transduction, kinase activity, membrane, membrane protein ectodomain proteolysis, metal ion binding, microtubule organizing center, negative regulation of insulin receptor signaling pathway, negative regulation of T cell apoptotic process, nucleotide binding

Bgee · 19

PRKCQ → ankle, biceps brachii, choroid plexus of fourth ventricle, deltoid muscle, digastric muscle, Epithelium of choroid plexus, glutes, habenula, muscle of thigh, retinal pigment epithelium, seminiferous tubule, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle

RNA expression pattern · 19

Band · 2

PRKCQ → 10p15.1, 2 A1|2 8.42 cM

Chr. · 2

PRKCQ → Chromosome 10 (human), Chromosome 2 (mouse)

End · 2

PRKCQ → 11,306,033 bp, 6,580,301 bp

related to Interactions · 2

PRKCQ → AKT1FYN, GLRX3

2.7.11.13 · 1

PRKCQ → ↗

Aliases · 1

PRKCQ → PRKCQ, PRKCT, nPKC-theta, protein kinase C theta

Available structures · 1

PRKCQ → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XJD, 2ENJ, 2ENN, 2ENZ, 2JED, 4Q9Z, 4RA5, 5F9E

Important terminology Word statistics

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Important terminology

pkc-θ cells kinase protein role bp gene inhibitors activation chr human band transcription tcr pkc chromosome 10 immunological synapse family

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PRKCQ	2.7.11.13	↗	1.00	infobox
PRKCQ	Aliases	PRKCQ, PRKCT, nPKC-theta, protein kinase C theta	1.00	infobox
PRKCQ	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XJD, 2ENJ, 2ENN, 2ENZ, 2JED, 4Q9Z, 4RA5, 5F9E	1.00	infobox
PRKCQ	Band	10p15.1	1.00	infobox
PRKCQ	Band	2 A1\|2 8.42 cM	1.00	infobox
PRKCQ	Bgee	triceps brachii muscle	1.00	infobox
PRKCQ	Bgee	glutes	1.00	infobox
PRKCQ	Bgee	biceps brachii	1.00	infobox
PRKCQ	Bgee	vastus lateralis muscle	1.00	infobox
PRKCQ	Bgee	Skeletal muscle tissue of biceps brachii	1.00	infobox
PRKCQ	Bgee	Skeletal muscle tissue of rectus abdominis	1.00	infobox
PRKCQ	Bgee	thoracic diaphragm	1.00	infobox
PRKCQ	Bgee	deltoid muscle	1.00	infobox
PRKCQ	Bgee	muscle of thigh	1.00	infobox
PRKCQ	Bgee	tibialis anterior muscle	1.00	infobox
PRKCQ	Bgee	habenula	1.00	infobox
PRKCQ	Bgee	ankle	1.00	infobox
PRKCQ	Bgee	temporal muscle	1.00	infobox
PRKCQ	Bgee	retinal pigment epithelium	1.00	infobox
PRKCQ	Bgee	sternocleidomastoid muscle	1.00	infobox
PRKCQ	Bgee	digastric muscle	1.00	infobox
PRKCQ	Bgee	Epithelium of choroid plexus	1.00	infobox
PRKCQ	Bgee	seminiferous tubule	1.00	infobox
PRKCQ	Bgee	choroid plexus of fourth ventricle	1.00	infobox
PRKCQ	BioGPS	More reference expression data	1.00	infobox
PRKCQ	Chr.	Chromosome 10 (human)	1.00	infobox
PRKCQ	Chr.	Chromosome 2 (mouse)	1.00	infobox
PRKCQ	Databases	NCBI: entry; OMA: entry	1.00	infobox
PRKCQ	End	6,580,301 bp	1.00	infobox
PRKCQ	End	11,306,033 bp	1.00	infobox

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