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MAP3K11: Interactions, Function & Overview

Mitogen-activated protein kinase kinase kinase 11 is an enzyme that in humans is encoded by the MAP3K11 gene.

Language: English [EN]
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MAP3K11 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around MAP3K11.

Related topics
9
Source areas
3
Connected nodes
12
Extracted relationships
98
Concept neighborhoods
8
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.25
Aliases
MAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK, mitogen-activated protein kinase kinase kinase 11
Band
11q13.1 · 19 A|19 4.34 cM
Bgee
sural nerve · granulocyte · apex of heart · mucosa of transverse colon · right lobe of liver
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAP3K11 connects Entity context

The extracted context around MAP3K11 shows recurring relationship patterns in the source. For example, MAP3K11 → ATP binding, cell death, cell population proliferation, centrosome, cytoplasm, cytoskeleton, identical protein binding, intracellular anatomical structure, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, membrane, microtubule, microtubule organizing center, microtubule-based process, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, nucleotide binding Another extracted example is MAP3K11 → apex of heart, C1 segment, crypt of lieberkuhn of small intestine, external carotid artery, granulocyte, internal carotid artery, intestinal villus, lip, monocyte, mucosa of transverse colon, right kidney, right lobe of liver, right lung, spleen, sural nerve, thymus, upper lobe of left lung, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAP3K11

Top relations

Gene ontology · 34
MAP3K11 → ATP binding, cell death, cell population proliferation, centrosome, cytoplasm, cytoskeleton, identical protein binding, intracellular anatomical structure, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, membrane, microtubule, microtubule organizing center, microtubule-based process, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, nucleotide binding
Bgee · 19
MAP3K11 → apex of heart, C1 segment, crypt of lieberkuhn of small intestine, external carotid artery, granulocyte, internal carotid artery, intestinal villus, lip, monocyte, mucosa of transverse colon, right kidney, right lobe of liver, right lung, spleen, sural nerve, thymus, upper lobe of left lung, yolk sac, zygote
RNA expression pattern · 19
MAP3K11 → apex of heart, C1 segment, crypt of lieberkuhn of small intestine, external carotid artery, granulocyte, internal carotid artery, intestinal villus, lip, monocyte, mucosa of transverse colon, right kidney, right lobe of liver, right lung, spleen, sural nerve, thymus, upper lobe of left lung, yolk sac, zygote
related to Interactions · 4
MAP3K11 → AKT1, CDC42, MAPK8IP1, MAPK8IP2
Band · 2
MAP3K11 → 11q13.1, 19 A|19 4.34 cM
Chr. · 2
MAP3K11 → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
MAP3K11 → 5,752,893 bp, 65,615,382 bp
2.7.11.25 · 1
MAP3K11 → ↗
Aliases · 1
MAP3K11 → MAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK, mitogen-activated protein kinase kinase kinase 11
BioGPS · 1
MAP3K11 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

kinase bp 11 gene chr human band protein chromosome mitogen-activated location activity enzyme mouse jnk function encoded external 615 382

MAP3K11 relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around MAP3K11. Examples in this analysis include MAP3K11 → 2.7.11.25 → ↗ and MAP3K11 → Aliases → MAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK, mitogen-activated protein kinase kinase kinase 11. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAP3K112.7.11.251.00infobox
MAP3K11AliasesMAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK, mitogen-activated protein kinase kinase kinase 111.00infobox
MAP3K11Band11q13.11.00infobox
MAP3K11Band19 A|19 4.34 cM1.00infobox
MAP3K11Bgeesural nerve1.00infobox
MAP3K11Bgeegranulocyte1.00infobox
MAP3K11Bgeeapex of heart1.00infobox
MAP3K11Bgeemucosa of transverse colon1.00infobox
MAP3K11Bgeeright lobe of liver1.00infobox
MAP3K11Bgeemonocyte1.00infobox
MAP3K11Bgeeright lung1.00infobox
MAP3K11Bgeespleen1.00infobox
MAP3K11BgeeC1 segment1.00infobox
MAP3K11Bgeeupper lobe of left lung1.00infobox
MAP3K11Bgeeyolk sac1.00infobox
MAP3K11Bgeelip1.00infobox
MAP3K11Bgeeexternal carotid artery1.00infobox
MAP3K11Bgeeinternal carotid artery1.00infobox
MAP3K11Bgeeintestinal villus1.00infobox
MAP3K11Bgeeright kidney1.00infobox
MAP3K11Bgeethymus1.00infobox
MAP3K11Bgeecrypt of lieberkuhn of small intestine1.00infobox
MAP3K11Bgeezygote1.00infobox
MAP3K11BioGPSMore reference expression data1.00infobox
MAP3K11Chr.Chromosome 11 (human)1.00infobox
MAP3K11Chr.Chromosome 19 (mouse)1.00infobox
MAP3K11DatabasesNCBI: entry; OMA: entry1.00infobox
MAP3K11End65,615,382 bp1.00infobox
MAP3K11End5,752,893 bp1.00infobox
MAP3K11EnsemblENSG000001733271.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAP3K11 bring nearby vocabulary together. In this analysis, examples include Mitogen-activated, Protein and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAP3K11
    • Mitogen-activated
    • Protein
    • Gene
    • External
    • Function
    • Mlk3
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • map3k11
    • Mitogen-activated
    • Protein
    • Gene
    • External
    • Function
    • Mlk3
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • gene
    • Location
    • Mitogen-activated
    • Protein
    • Chromosome
    • Human
    • Map3k11
    • Bp
    • Chr
    • End
    • External
    • Function
    • Mlk3
  • kinase
    • Activity
    • Jnk
    • Mitogen-activated
    • Protein
    • Gene
    • Map3k11
    • Activates
    • Encoded
    • Enzyme
    • External
    • Family
    • Function
  • function
    • External
    • Mlk3
    • Activity
    • Location
    • Mitogen-activated
    • Protein
    • Chromosome
    • Gene
    • Human
    • Interactions
    • Map3k11
    • Reading
  • enzyme
    • Mitogen-activated
    • Protein
    • Gene
    • Humans
    • Interactions
    • Map3k11
    • Reading
    • References
    • Encoded
    • External
    • Function
    • Kinase
  • interactions
    • Reading
    • References
    • Mlk3
    • Location
    • Mitogen-activated
    • Protein
    • Human
    • Map3k11
    • Kinase
  • cdc42
    • Family
    • Jnk
    • Map3k11
    • Kinase

Connections between topic areas Semantic bridges

For MAP3K11, one of the stronger structural bridges in this analysis connects MAP3K11 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAP3K11Interactions · splits 6 ⟂ 7
MAP3K11Overview · splits 10 ⟂ 3

Map overview Semantic statistics

MAP3K11

Nodes13
Edges12
Triples98
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around MAP3K11 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAP3K11 · EN edition · Analysis: TopicsToTalkAbout

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