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MAPK14

Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.

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2.7.11.24
Aliases
MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A9U, 1BL6, 1BL7, 1BMK, 1DI9, 1IAN, 1KV1, 1KV2, 1M7Q, 1OUK, 1OUY, 1OVE, 1OZ1, 1R39, 1R3C, 1W7H, 1W82, 1W83,…
Band
6p21.31 · 17 A3.3|17 14.85 cM
Bgee
buccal mucosa cell · blood · bone marrow · bone marrow cell · monocyte
BioGPS
More reference expression data

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MAPK14

Nodes48
Edges47
Triples185
Avg. degree1.96
Density0.041667
Components1

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MAPK14

Top relations

Gene ontology · 89
MAPK14 → 3'-UTR-mediated mRNA stabilization, angiogenesis, apoptotic process, ATP binding, cartilage condensation, cell morphogenesis, cell surface receptor signaling pathway, cellular response to DNA damage stimulus, cellular response to ionizing radiation, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to organic substance, cellular response to tumor necrosis factor, cellular response to vascular endothelial growth factor stimulus, chemotaxis, chondrocyte differentiation, cytoplasm, cytosol, DNA damage checkpoint signaling, enzyme binding
Bgee · 18
MAPK14 → Achilles tendon, blood, bone marrow, bone marrow cell, buccal mucosa cell, conjunctival fornix, endothelial cell, granulocyte, knee joint, masseter muscle, medullary collecting duct, monocyte, primitive streak, renal corpuscle, stromal cell of endometrium, trabecular bone, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 18
MAPK14 → Achilles tendon, blood, bone marrow, bone marrow cell, buccal mucosa cell, conjunctival fornix, endothelial cell, granulocyte, knee joint, masseter muscle, medullary collecting duct, monocyte, primitive streak, renal corpuscle, stromal cell of endometrium, trabecular bone, triceps brachii muscle, vastus lateralis muscle
related to Interactions · 17
MAPK14 → AKT1, ATF2, CDC25B, CDC25C, CSNK2A1, DUSP1, DUSP10, DUSP16, FUBP1, HTRA2, KRT8MAP2K6, MAPK1, MAPKAPK2, MAPKAPK3, MEF2A, RPS6KA4, TAB1
Band · 2
MAPK14 → 17 A3.3|17 14.85 cM, 6p21.31
Chr. · 2
MAPK14 → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
MAPK14 → 28,967,380 bp, 36,111,236 bp
2.7.11.24 · 1
MAPK14 → ↗
Aliases · 1
MAPK14 → MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14
Available structures · 1
MAPK14 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A9U, 1BL6, 1BL7, 1BMK, 1DI9, 1IAN, 1KV1, 1KV2, 1M7Q, 1OUK, 1OUY, 1OVE, 1OZ1, 1R39, 1R3C, 1W7H, 1W82, 1W83,…

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Important terminology

mapk p38 p38α kinase protein activity activation also gene phosphorylation cell human bp response addition heart mitogen-activated transcription map 14

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MAPK142.7.11.241.00infobox
MAPK14AliasesMAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 141.00infobox
MAPK14Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A9U, 1BL6, 1BL7, 1BMK, 1DI9, 1IAN, 1KV1, 1KV2, 1M7Q, 1OUK, 1OUY, 1OVE, 1OZ1, 1R39, 1R3C, 1W7H, 1W82, 1W83,…1.00infobox
MAPK14Band6p21.311.00infobox
MAPK14Band17 A3.3|17 14.85 cM1.00infobox
MAPK14Bgeebuccal mucosa cell1.00infobox
MAPK14Bgeeblood1.00infobox
MAPK14Bgeebone marrow1.00infobox
MAPK14Bgeebone marrow cell1.00infobox
MAPK14Bgeemonocyte1.00infobox
MAPK14Bgeetrabecular bone1.00infobox
MAPK14BgeeAchilles tendon1.00infobox
MAPK14Bgeeendothelial cell1.00infobox
MAPK14Bgeegranulocyte1.00infobox
MAPK14Bgeestromal cell of endometrium1.00infobox
MAPK14Bgeerenal corpuscle1.00infobox
MAPK14Bgeemedullary collecting duct1.00infobox
MAPK14Bgeeconjunctival fornix1.00infobox
MAPK14Bgeeknee joint1.00infobox
MAPK14Bgeetriceps brachii muscle1.00infobox
MAPK14Bgeeprimitive streak1.00infobox
MAPK14Bgeemasseter muscle1.00infobox
MAPK14Bgeevastus lateralis muscle1.00infobox
MAPK14BioGPSMore reference expression data1.00infobox
MAPK14Chr.Chromosome 6 (human)1.00infobox
MAPK14Chr.Chromosome 17 (mouse)1.00infobox
MAPK14DatabasesNCBI: entry; OMA: entry1.00infobox
MAPK14End36,111,236 bp1.00infobox
MAPK14End28,967,380 bp1.00infobox
MAPK14EnsemblENSG000001120621.00infobox

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