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Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around MAPK14.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAPK14 shows recurring relationship patterns in the source. For example, MAPK14 → 3'-UTR-mediated mRNA stabilization, angiogenesis, apoptotic process, ATP binding, cartilage condensation, cell morphogenesis, cell surface receptor signaling pathway, cellular response to DNA damage stimulus, cellular response to ionizing radiation, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to organic substance, cellular response to tumor necrosis factor, cellular response to vascular endothelial growth factor stimulus, chemotaxis, chondrocyte differentiation, cytoplasm, cytosol, DNA damage checkpoint signaling, enzyme binding Another extracted example is MAPK14 → Achilles tendon, blood, bone marrow, bone marrow cell, buccal mucosa cell, conjunctival fornix, endothelial cell, granulocyte, knee joint, masseter muscle, medullary collecting duct, monocyte, primitive streak, renal corpuscle, stromal cell of endometrium, trabecular bone, triceps brachii muscle, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
mapk p38 p38α kinase protein activity activation also gene phosphorylation cell human bp response addition heart mitogen-activated transcription map 14
TTTA extracted 185 structured relationships around MAPK14. Examples in this analysis include MAPK14 → 2.7.11.24 → ↗ and MAPK14 → Aliases → MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAPK14 | 2.7.11.24 | ↗ | 1.00 | infobox |
| MAPK14 | Aliases | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14 | 1.00 | infobox |
| MAPK14 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A9U, 1BL6, 1BL7, 1BMK, 1DI9, 1IAN, 1KV1, 1KV2, 1M7Q, 1OUK, 1OUY, 1OVE, 1OZ1, 1R39, 1R3C, 1W7H, 1W82, 1W83,… | 1.00 | infobox |
| MAPK14 | Band | 6p21.31 | 1.00 | infobox |
| MAPK14 | Band | 17 A3.3|17 14.85 cM | 1.00 | infobox |
| MAPK14 | Bgee | buccal mucosa cell | 1.00 | infobox |
| MAPK14 | Bgee | blood | 1.00 | infobox |
| MAPK14 | Bgee | bone marrow | 1.00 | infobox |
| MAPK14 | Bgee | bone marrow cell | 1.00 | infobox |
| MAPK14 | Bgee | monocyte | 1.00 | infobox |
| MAPK14 | Bgee | trabecular bone | 1.00 | infobox |
| MAPK14 | Bgee | Achilles tendon | 1.00 | infobox |
| MAPK14 | Bgee | endothelial cell | 1.00 | infobox |
| MAPK14 | Bgee | granulocyte | 1.00 | infobox |
| MAPK14 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| MAPK14 | Bgee | renal corpuscle | 1.00 | infobox |
| MAPK14 | Bgee | medullary collecting duct | 1.00 | infobox |
| MAPK14 | Bgee | conjunctival fornix | 1.00 | infobox |
| MAPK14 | Bgee | knee joint | 1.00 | infobox |
| MAPK14 | Bgee | triceps brachii muscle | 1.00 | infobox |
| MAPK14 | Bgee | primitive streak | 1.00 | infobox |
| MAPK14 | Bgee | masseter muscle | 1.00 | infobox |
| MAPK14 | Bgee | vastus lateralis muscle | 1.00 | infobox |
| MAPK14 | BioGPS | More reference expression data | 1.00 | infobox |
| MAPK14 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| MAPK14 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| MAPK14 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAPK14 | End | 36,111,236 bp | 1.00 | infobox |
| MAPK14 | End | 28,967,380 bp | 1.00 | infobox |
| MAPK14 | Ensembl | ENSG00000112062 | 1.00 | infobox |
The concept neighborhoods around MAPK14 bring nearby vocabulary together. In this analysis, examples include Mitogen-activated, Protein and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAPK14, one of the stronger structural bridges in this analysis connects MAPK14 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAPK14 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAPK14 · EN edition · Analysis: TopicsToTalkAbout