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P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent…
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p-gp expression protein abcb1 drugs gene also cells drug substrates resistance xenobiotics cell substrate binding multidrug intestinal inhibitors many human
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| P-glycoprotein | 7.6.2.1 | ↗ | 1.00 | infobox |
| P-glycoprotein | 7.6.2.2 | ↗ | 1.00 | infobox |
| P-glycoprotein | Aliases | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, ATP binding cassette subfamily B member 1, P-glycoprotein, P-gp, Pgp | 1.00 | infobox |
| P-glycoprotein | Band | 5 A1|5 3.43 cM | 1.00 | infobox |
| P-glycoprotein | Bgee | left colon | 1.00 | infobox |
| P-glycoprotein | Bgee | iris | 1.00 | infobox |
| P-glycoprotein | Bgee | Paneth cell | 1.00 | infobox |
| P-glycoprotein | Bgee | jejunum | 1.00 | infobox |
| P-glycoprotein | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| P-glycoprotein | Bgee | ileum | 1.00 | infobox |
| P-glycoprotein | Bgee | gallbladder | 1.00 | infobox |
| P-glycoprotein | Bgee | ciliary body | 1.00 | infobox |
| P-glycoprotein | Bgee | intestinal villus | 1.00 | infobox |
| P-glycoprotein | Bgee | substantia nigra | 1.00 | infobox |
| P-glycoprotein | BioGPS | More reference expression data | 1.00 | infobox |
| P-glycoprotein | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| P-glycoprotein | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| P-glycoprotein | End | 8,798,575 bp | 1.00 | infobox |
| P-glycoprotein | Ensembl | ENSG00000085563 | 1.00 | infobox |
| P-glycoprotein | Entrez | 5243 | 1.00 | infobox |
| P-glycoprotein | Enzyme activity | Enzyme activityEC #BRENDAExPASyKEGGMetaCyc7.6.2.1↗↗↗↗7.6.2.2↗↗↗↗ | 1.00 | infobox |
| P-glycoprotein | External IDs | OMIM: 171050; MGI: 97570; GeneCards: ABCB1 | 1.00 | infobox |
| P-glycoprotein | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 5 (mouse)Band5 A1|5 3.43 cMStart8,710,077 bpEnd8,798,575 bp | 1.00 | infobox |
| P-glycoprotein | Gene ontology | ATPase-coupled transmembrane transporter activity | 1.00 | infobox |
| P-glycoprotein | Gene ontology | nucleotide binding | 1.00 | infobox |
| P-glycoprotein | Gene ontology | transporter activity | 1.00 | infobox |
| P-glycoprotein | Gene ontology | ATPase activity | 1.00 | infobox |
| P-glycoprotein | Gene ontology | protein binding | 1.00 | infobox |
| P-glycoprotein | Gene ontology | hydrolase activity | 1.00 | infobox |
| P-glycoprotein | Gene ontology | ATP binding | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
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