ZEB1

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Clinical significance

Posterior polymorphous corneal dystrophy 3 E-cadherin Epithelial to mesenchymal transition Carcinomas Lung cancer

5 related topics

Overview

Protein Gene Zinc finger Homeodomain Transcription factor

9 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ZEB1, zinc finger E-box binding homeobox 1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E19
Band: 10p11.22 · 18 4.42 cM|18 A1
Bgee: Achilles tendon · epithelium of colon · decidua · optic nerve · glutes
BioGPS: More reference expression data
Chr.: Chromosome 10 (human) · Chromosome 18 (mouse)

Topics to explore

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Overview

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes17

Edges16

Triples113

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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ZEB1

Top relations

Gene ontology · 46

ZEB1 → animal organ development, cartilage development, cell differentiation, cell population proliferation, cellular response to amino acid stimulus, central nervous system development, chromatin binding, cochlea morphogenesis, cytokine-mediated signaling pathway, cytosol, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, E-box binding, embryonic camera-type eye morphogenesis, embryonic morphogenesis, embryonic skeletal system morphogenesis, immune response, metal ion binding

Bgee · 20

ZEB1 → Achilles tendon, ascending aorta, biceps brachii, carotid body, decidua, endothelial cell, epithelium of colon, external carotid artery, glutes, Gonadal ridge, internal carotid artery, motor neuron, optic nerve, Rostral migratory stream, semi-lunar valve, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, substantia nigra, suprachiasmatic nucleus, tendon of biceps brachii

RNA expression pattern · 20

related to Clinical significance · 3

ZEB1 → E-cadherin, Mutations, Overexpression

Band · 2

ZEB1 → 10p11.22, 18 4.42 cM|18 A1

Chr. · 2

ZEB1 → Chromosome 10 (human), Chromosome 18 (mouse)

End · 2

ZEB1 → 31,529,814 bp, 5,775,467 bp

Aliases · 1

ZEB1 → ZEB1, zinc finger E-box binding homeobox 1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A

Available structures · 1

ZEB1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E19

BioGPS · 1

ZEB1 → More reference expression data

Important terminology Word statistics

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Important terminology

zinc gene homeodomain bp chr finger human band protein chromosome 10 transcription binding external factor location mouse homeobox tcf8 expression

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
ZEB1	Aliases	ZEB1, zinc finger E-box binding homeobox 1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A	1.00	infobox
ZEB1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E19	1.00	infobox
ZEB1	Band	10p11.22	1.00	infobox
ZEB1	Band	18 4.42 cM\|18 A1	1.00	infobox
ZEB1	Bgee	Achilles tendon	1.00	infobox
ZEB1	Bgee	epithelium of colon	1.00	infobox
ZEB1	Bgee	decidua	1.00	infobox
ZEB1	Bgee	optic nerve	1.00	infobox
ZEB1	Bgee	glutes	1.00	infobox
ZEB1	Bgee	endothelial cell	1.00	infobox
ZEB1	Bgee	Skeletal muscle tissue of rectus abdominis	1.00	infobox
ZEB1	Bgee	biceps brachii	1.00	infobox
ZEB1	Bgee	tendon of biceps brachii	1.00	infobox
ZEB1	Bgee	Skeletal muscle tissue of biceps brachii	1.00	infobox
ZEB1	Bgee	internal carotid artery	1.00	infobox
ZEB1	Bgee	substantia nigra	1.00	infobox
ZEB1	Bgee	motor neuron	1.00	infobox
ZEB1	Bgee	external carotid artery	1.00	infobox
ZEB1	Bgee	semi-lunar valve	1.00	infobox
ZEB1	Bgee	carotid body	1.00	infobox
ZEB1	Bgee	ascending aorta	1.00	infobox
ZEB1	Bgee	Rostral migratory stream	1.00	infobox
ZEB1	Bgee	suprachiasmatic nucleus	1.00	infobox
ZEB1	Bgee	Gonadal ridge	1.00	infobox
ZEB1	BioGPS	More reference expression data	1.00	infobox
ZEB1	Chr.	Chromosome 10 (human)	1.00	infobox
ZEB1	Chr.	Chromosome 18 (mouse)	1.00	infobox
ZEB1	Databases	NCBI: entry; OMA: entry	1.00	infobox
ZEB1	End	31,529,814 bp	1.00	infobox
ZEB1	End	5,775,467 bp	1.00	infobox

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