Vortioxetine

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Vortioxetine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Vortioxetine.

Related topics: 159
Source areas: 10
Connected nodes: 169
Extracted relationships: 111
Related term clusters: 48
Bridge connections: 169

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 68 topics

Interactions · 31 topics

Overview · 23 topics

Adverse effects · 10 topics

Medical uses · 9 topics

Research · 7 topics

History · 5 topics

Chemistry · 3 topics

Contraindications · 2 topics

Society and culture · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol): Interactive image
AHFS/Drugs.com: Monograph
ATC code: N06AX26 (WHO)
Bioavailability: 75% (peak at 7–11 hours)
CAS Number: 508233-74-7 Y
ChEBI: CHEBI:76016 Y

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Vortioxetine

5Antidepressant · Serotonin modulator and stimulator · Major depressive disorder

8Clearance (pharmacology) · Elimination half-life · Elimination (pharmacology)

6Metabolism · Cytochrome P450 · CYP2D6

18Side effect · Nausea · Dry mouth

6Off-label use · Anxiety · Generalized anxiety disorder

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Medical uses

Contraindications

Adverse effects

Pharmacology

Chemistry

History

Society and culture

Ticagrelor

Research

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Vortioxetine connects Entity context

The extracted context around Vortioxetine shows recurring relationship patterns in the source. For example, Vortioxetine → Brilinta, Brintellix, Drug Administration, FDA, May, Torvox, Trintellix, Trivoxetin, United States, US Food, Vantaxa, Vatoin, Vipca, Vortica, Vortidif, Voxigain, Xomat Another extracted example is Vortioxetine → EC50, HT1A, HT1B, HT1D, HT3, HT7, IC50, Occupancy, REM, SERT, Whereas. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Names · 17

Vortioxetine → Brilinta, Brintellix, Drug Administration, FDA, May, Torvox, Trintellix, Trivoxetin, United States, US Food, Vantaxa, Vatoin, Vipca, Vortica, Vortidif, Voxigain, Xomat

related to Pharmacodynamics · 11

Vortioxetine → EC50, HT1A, HT1B, HT1D, HT3, HT7, IC50, Occupancy, REM, SERT, Whereas

has effect · 10

Vortioxetine → Arizona Sexual Experience Scale, ASEX, Discontinuation, Incidence, Sexual, Significant, SNRI, SNRIs, SSRI, SSRIs

related to Pharmacogenomics · 8

Vortioxetine → Area-under-the-curve, CYP2C19, CYP2D6, Depending, Dosage, Genetic, L/h, P450

Legal status · 7

Vortioxetine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only

related to history · 7

Vortioxetine → Japan, Lu AA21004, Lu AA24530, Lundbeck, Phase II, Takeda, US

related to Interactions · 5

Vortioxetine → Bupropion, CYP2D6, Inhibitors, Lesser, P450

related to Pharmacokinetics · 3

Vortioxetine → Food, Peak, Steady-state

KEGG · 2

Vortioxetine → as salt: D10185 Y, D10184 Y

UNII · 2

Vortioxetine → 3O2K1S3WQV, as salt: TKS641KOAY

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

serotonin may cyp2d6 effects 5-ht3 mg receptor sexual dysfunction levels anxiety found day nausea disorder side pharmacokinetics receptors ssris also

Vortioxetine relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around Vortioxetine. Examples in this analysis include Vortioxetine → 3D model (JSmol) → Interactive image and Vortioxetine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Vortioxetine	3D model (JSmol)	Interactive image	1.00	infobox
Vortioxetine	AHFS/Drugs.com	Monograph	1.00	infobox
Vortioxetine	ATC code	N06AX26 (WHO)	1.00	infobox
Vortioxetine	Bioavailability	75% (peak at 7–11 hours)	1.00	infobox
Vortioxetine	CAS Number	508233-74-7 Y	1.00	infobox
Vortioxetine	ChEBI	CHEBI:76016 Y	1.00	infobox
Vortioxetine	ChEMBL	ChEMBL2204360 Y	1.00	infobox
Vortioxetine	ChemSpider	8141643 Y	1.00	infobox
Vortioxetine	CompTox Dashboard (EPA)	DTXSID80965062	1.00	infobox
Vortioxetine	Drug class	Serotonin modulator and stimulator (SMS)	1.00	infobox
Vortioxetine	DrugBank	DB09068 Y	1.00	infobox
Vortioxetine	ECHA InfoCard	100.258.748	1.00	infobox
Vortioxetine	Elimination half-life	66 hours	1.00	infobox
Vortioxetine	Excretion	59% in urine, 26% in feces	1.00	infobox
Vortioxetine	Formula	C18H22N2S	1.00	infobox
Vortioxetine	IUPHAR/BPS	7351	1.00	infobox
Vortioxetine	KEGG	D10184 Y	1.00	infobox
Vortioxetine	KEGG	as salt: D10185 Y	1.00	infobox
Vortioxetine	Legal status	AU: S4 (Prescription only)	1.00	infobox
Vortioxetine	Legal status	BR: Class C1 (Other controlled substances)	1.00	infobox
Vortioxetine	Legal status	CA: ℞-only	1.00	infobox
Vortioxetine	Legal status	UK: POM (Prescription only)	1.00	infobox
Vortioxetine	Legal status	US: ℞-only	1.00	infobox
Vortioxetine	Legal status	EU: Rx-only	1.00	infobox
Vortioxetine	Legal status	In general: ℞ (Prescription only)	1.00	infobox
Vortioxetine	License data	US DailyMed: Vortioxetine	1.00	infobox
Vortioxetine	MedlinePlus	a614003	1.00	infobox
Vortioxetine	Metabolism	Liver, primarily CYP2D6-mediated oxidation	1.00	infobox
Vortioxetine	Molar mass	298.45 g·mol−1	1.00	infobox
Vortioxetine	Other names	Lu AA21004, Vortioxetine hydrobromide (JAN JP), Vortioxetine hydrobromide (USAN US)	1.00	infobox

Related concept clusters Related term clusters

The concept neighborhoods around Vortioxetine bring nearby vocabulary together. In this analysis, examples include Serotonin, May and Mg. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Vortioxetine
- Serotonin
- May
- Mg
- Cyp2d6
- Day
- Receptor
- Levels
- Cytochrome
- P450
- Treatment
- Anxiety
- Disorder
vortioxetine
- Serotonin
- May
- Mg
- Cyp2d6
- Day
- Receptor
- Levels
- Cytochrome
- P450
- Treatment
- Anxiety
- Disorder
serotonin modulator and stimulator
- Reuptake
- Receptor
- Receptors
- Vortioxetine
- 5-ht3
- May
- Syndrome
- Effects
- Occupancy
- Ssris
- Inhibitors
- Used
side effects
- Side
- Nausea
- Dysfunction
- Sexual
- Serotonin
- Ssris
- May
- Reuptake
- Treatment
- Receptor
- Vortioxetine
- Inhibitors
serotonin syndrome
- Reuptake
- Receptor
- Receptors
- Vortioxetine
- 5-ht3
- May
- Syndrome
- Effects
- Occupancy
- Ssris
- Inhibitors
- Used
serotonin
- Reuptake
- Receptor
- Receptors
- Vortioxetine
- 5-ht3
- May
- Syndrome
- Effects
- Occupancy
- Ssris
- Inhibitors
- Used
serotonin modulators and stimulators
- Reuptake
- Receptor
- Receptors
- Vortioxetine
- 5-ht3
- May
- Syndrome
- Effects
- Occupancy
- Ssris
- Inhibitors
- Used
serotonin transporter
- Reuptake
- Receptor
- Receptors
- Vortioxetine
- 5-ht3
- May
- Syndrome
- Effects
- Occupancy
- Ssris
- Inhibitors
- Used

Connections between topic areas Semantic bridges

For Vortioxetine, one of the stronger structural bridges in this analysis connects Vortioxetine with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Vortioxetine — Pharmacology · splits 101 ⟂ 69

Vortioxetine — Interactions · splits 138 ⟂ 32

Vortioxetine — Overview · splits 146 ⟂ 24

Vortioxetine — Adverse effects · splits 159 ⟂ 11

Vortioxetine — Medical uses · splits 160 ⟂ 10

Vortioxetine — Research · splits 162 ⟂ 8

Vortioxetine — History · splits 164 ⟂ 6

Vortioxetine — Chemistry · splits 166 ⟂ 4

Vortioxetine — Contraindications · splits 167 ⟂ 3

Map overview Semantic statistics

Vortioxetine

Nodes170

Edges169

Triples111

Avg. degree1.99

Density0.011765

Components1

Source & methodology

TTTA analyzes the structure around Vortioxetine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Vortioxetine · EN edition · Analysis: TopicsToTalkAbout

Vortioxetine: History, Community, Culture & Applications

Vortioxetine topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

For the semantics nerds

Advanced semantic analysis

How Vortioxetine connects Entity context

Vortioxetine

Top relations

Important terminology

Important terminology

Vortioxetine relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Vortioxetine

Source & methodology