Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Vortioxetine: History, Community, Culture & Applications

Vortioxetine, sold under the brand names Trintellix (in the US) and Brintellix (in Europe) among others, is an antidepressant medication of the serotonin modulator and stimulator (SMS) class used in the treatment of major depressive disorder. Its effectiveness is viewed as similar to that of other antidepressants. It is taken orally.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Vortioxetine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Vortioxetine.

Related topics
159
Source areas
10
Connected nodes
169
Extracted relationships
135
Concept neighborhoods
48
Bridge connections
169

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 68 topics
Interactions · 31 topics
Overview · 23 topics
Adverse effects · 10 topics
Medical uses · 9 topics
Research · 7 topics
History · 5 topics
Chemistry · 3 topics
Contraindications · 2 topics
Society and culture · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06AX26 (WHO)
Bioavailability
75% (peak at 7–11 hours)
CAS Number
508233-74-7 Y
ChEBI
CHEBI:76016 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Vortioxetine connects Entity context

The extracted context around Vortioxetine shows recurring relationship patterns in the source. For example, Vortioxetine → Brilinta, Brintellix, Drug Administration, FDA, May, Other, Torvox, Trintellix, Trivoxetin, United States, US Food, Vantaxa, Vatoin, Vipca, Vortica, Vortidif, Voxigain, Xomat Another extracted example is Vortioxetine → Arizona Sexual Experience Scale, ASEX, Discontinuation, However, In, Incidence, Sexual, Significant, SNRI, SNRIs, SSRI, SSRIs, The, These, With. Use these groups to spot repeated connection types before inspecting the individual relationships.

Vortioxetine

Top relations

related to Names · 18
Vortioxetine → Brilinta, Brintellix, Drug Administration, FDA, May, Other, Torvox, Trintellix, Trivoxetin, United States, US Food, Vantaxa, Vatoin, Vipca, Vortica, Vortidif, Voxigain, Xomat
has effect · 15
Vortioxetine → Arizona Sexual Experience Scale, ASEX, Discontinuation, However, In, Incidence, Sexual, Significant, SNRI, SNRIs, SSRI, SSRIs, The, These, With
related to Pharmacodynamics · 15
Vortioxetine → EC50, HT1A, HT1B, HT1D, HT3, HT7, IC50, In, More, Occupancy, REM, SERT, The, This, Whereas
related to Pharmacogenomics · 11
Vortioxetine → Area-under-the-curve, CYP2C19, CYP2D6, Depending, Dosage, Genetic, However, In, L/h, P450, The
related to history · 9
Vortioxetine → In, Japan, Lu AA21004, Lu AA24530, Lundbeck, Phase II, Takeda, The, US
Legal status · 7
Vortioxetine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Interactions · 7
Vortioxetine → Bupropion, CYP2D6, Inhibitors, Lesser, Other, P450, The
related to Pharmacokinetics · 5
Vortioxetine → Food, It, Peak, Steady-state, The
related to Research · 5
Vortioxetine → As, August, II, It, There
related to Medical uses · 3
Vortioxetine → Cochrane, However, SSRIs

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

serotonin may cyp2d6 effects 5-ht3 mg receptor sexual dysfunction levels anxiety found day nausea disorder side pharmacokinetics receptors ssris also

Vortioxetine relationships Subject–Predicate–Object triples

TTTA extracted 135 structured relationships around Vortioxetine. Examples in this analysis include Vortioxetine → 3D model (JSmol) → Interactive image and Vortioxetine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Vortioxetine3D model (JSmol)Interactive image1.00infobox
VortioxetineAHFS/Drugs.comMonograph1.00infobox
VortioxetineATC codeN06AX26 (WHO)1.00infobox
VortioxetineBioavailability75% (peak at 7–11 hours)1.00infobox
VortioxetineCAS Number508233-74-7 Y1.00infobox
VortioxetineChEBICHEBI:76016 Y1.00infobox
VortioxetineChEMBLChEMBL2204360 Y1.00infobox
VortioxetineChemSpider8141643 Y1.00infobox
VortioxetineCompTox Dashboard (EPA)DTXSID809650621.00infobox
VortioxetineDrug classSerotonin modulator and stimulator (SMS)1.00infobox
VortioxetineDrugBankDB09068 Y1.00infobox
VortioxetineECHA InfoCard100.258.7481.00infobox
VortioxetineElimination half-life66 hours1.00infobox
VortioxetineExcretion59% in urine, 26% in feces1.00infobox
VortioxetineFormulaC18H22N2S1.00infobox
VortioxetineIUPHAR/BPS73511.00infobox
VortioxetineKEGGD10184 Y1.00infobox
VortioxetineKEGGas salt: D10185 Y1.00infobox
VortioxetineLegal statusAU: S4 (Prescription only)1.00infobox
VortioxetineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
VortioxetineLegal statusCA: ℞-only1.00infobox
VortioxetineLegal statusUK: POM (Prescription only)1.00infobox
VortioxetineLegal statusUS: ℞-only1.00infobox
VortioxetineLegal statusEU: Rx-only1.00infobox
VortioxetineLegal statusIn general: ℞ (Prescription only)1.00infobox
VortioxetineLicense dataUS DailyMed: Vortioxetine1.00infobox
VortioxetineMedlinePlusa6140031.00infobox
VortioxetineMetabolismLiver, primarily CYP2D6-mediated oxidation1.00infobox
VortioxetineMolar mass298.45 g·mol−11.00infobox
VortioxetineOther namesLu AA21004, Vortioxetine hydrobromide (JAN JP), Vortioxetine hydrobromide (USAN US)1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Vortioxetine bring nearby vocabulary together. In this analysis, examples include Serotonin, May and Mg. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Vortioxetine
    • Serotonin
    • May
    • Mg
    • Cyp2d6
    • Day
    • Receptor
    • Levels
    • Cytochrome
    • P450
    • Treatment
    • Anxiety
    • Disorder
  • vortioxetine
    • Serotonin
    • May
    • Mg
    • Cyp2d6
    • Day
    • Receptor
    • Levels
    • Cytochrome
    • P450
    • Treatment
    • Anxiety
    • Disorder
  • serotonin modulator and stimulator
    • Reuptake
    • Receptor
    • Receptors
    • Vortioxetine
    • 5-ht3
    • May
    • Syndrome
    • Effects
    • Occupancy
    • Ssris
    • Inhibitors
    • Used
  • side effects
    • Side
    • Nausea
    • Dysfunction
    • Sexual
    • Serotonin
    • Ssris
    • May
    • Reuptake
    • Treatment
    • Receptor
    • Vortioxetine
    • Inhibitors
  • serotonin syndrome
    • Reuptake
    • Receptor
    • Receptors
    • Vortioxetine
    • 5-ht3
    • May
    • Syndrome
    • Effects
    • Occupancy
    • Ssris
    • Inhibitors
    • Used
  • serotonin
    • Reuptake
    • Receptor
    • Receptors
    • Vortioxetine
    • 5-ht3
    • May
    • Syndrome
    • Effects
    • Occupancy
    • Ssris
    • Inhibitors
    • Used
  • selective serotonin reuptake inhibitors
    • Reuptake
    • Serotonin
    • Receptor
    • Receptors
    • Vortioxetine
    • 5-ht3
    • May
    • Syndrome
    • Pharmacokinetics
    • Dosage
    • Inhibitors
    • Effects
  • serotonin–norepinephrine reuptake inhibitors
    • Reuptake
    • Serotonin
    • Receptor
    • Receptors
    • Vortioxetine
    • 5-ht3
    • May
    • Syndrome
    • Pharmacokinetics
    • Dosage
    • Inhibitors
    • Effects

Connections between topic areas Semantic bridges

For Vortioxetine, one of the stronger structural bridges in this analysis connects Vortioxetine with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Vortioxetine — Pharmacology · splits 101 ⟂ 69
Vortioxetine — Interactions · splits 138 ⟂ 32
Vortioxetine — Overview · splits 146 ⟂ 24
Vortioxetine — Adverse effects · splits 159 ⟂ 11
Vortioxetine — Medical uses · splits 160 ⟂ 10
Vortioxetine — Research · splits 162 ⟂ 8
Vortioxetine — History · splits 164 ⟂ 6
Vortioxetine — Chemistry · splits 166 ⟂ 4
Vortioxetine — Contraindications · splits 167 ⟂ 3

Map overview Semantic statistics

Vortioxetine

Nodes170
Edges169
Triples135
Avg. degree1.99
Density0.011765
Components1

Source & methodology

TTTA analyzes the structure around Vortioxetine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Vortioxetine · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.