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Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. CYP2A6 is the primary enzyme responsible for the oxidation of nicotine and cotinine. It is also involved in the metabolism of several pharmaceuticals, carcinogens, and a number of…
The analysis highlights Induction, Distribution and Overview as prominent areas in the source structure around CYP2A6.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CYP2A6 shows recurring relationship patterns in the source. For example, CYP2A6 → arachidonic acid epoxygenase activity, coumarin 7-hydroxylase activity, coumarin catabolic process, coumarin metabolic process, cytoplasm, cytoplasmic microtubule, endoplasmic reticulum, endoplasmic reticulum membrane, enzyme binding, epoxygenase P450 pathway, heme binding, intracellular membrane-bounded organelle, iron ion binding, membrane, metal ion binding, monooxygenase activity, organelle membrane, organic acid metabolic process, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Another extracted example is CYP2A6 → Brodmann area 10, cerebellar vermis, esophagus, frontal pole, hepatobiliary system, human kidney, liver, male germ cell, middle frontal gyrus, nasal epithelium, olfactory epithelium, paraflocculus of cerebellum, proximal tubule, respiratory epithelium, right kidney, right lobe of liver, sperm, thalamus, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
human gene bp p450 chromosome chr band location cytochrome 19 enzyme also involved metabolism body coumarin mouse ucsc member system
TTTA extracted 92 structured relationships around CYP2A6. Examples in this analysis include CYP2A6 → Aliases → CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, cytochrome P450 family 2 subfamily A member 6 and CYP2A6 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RUI, 1Z10, 1Z11, 2FDU, 2FDV, 2FDW, 2FDY, 3EBS, 3T3Q, 3T3R, 4EJJ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CYP2A6 | Aliases | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, cytochrome P450 family 2 subfamily A member 6 | 1.00 | infobox |
| CYP2A6 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RUI, 1Z10, 1Z11, 2FDU, 2FDV, 2FDW, 2FDY, 3EBS, 3T3Q, 3T3R, 4EJJ | 1.00 | infobox |
| CYP2A6 | Band | 19q13.2 | 1.00 | infobox |
| CYP2A6 | Band | 7 A3|7 15.54 cM | 1.00 | infobox |
| CYP2A6 | Bgee | right lobe of liver | 1.00 | infobox |
| CYP2A6 | Bgee | paraflocculus of cerebellum | 1.00 | infobox |
| CYP2A6 | Bgee | middle frontal gyrus | 1.00 | infobox |
| CYP2A6 | Bgee | frontal pole | 1.00 | infobox |
| CYP2A6 | Bgee | Brodmann area 10 | 1.00 | infobox |
| CYP2A6 | Bgee | nasal epithelium | 1.00 | infobox |
| CYP2A6 | Bgee | cerebellar vermis | 1.00 | infobox |
| CYP2A6 | Bgee | male germ cell | 1.00 | infobox |
| CYP2A6 | Bgee | sperm | 1.00 | infobox |
| CYP2A6 | Bgee | thalamus | 1.00 | infobox |
| CYP2A6 | Bgee | proximal tubule | 1.00 | infobox |
| CYP2A6 | Bgee | human kidney | 1.00 | infobox |
| CYP2A6 | Bgee | right kidney | 1.00 | infobox |
| CYP2A6 | Bgee | hepatobiliary system | 1.00 | infobox |
| CYP2A6 | Bgee | liver | 1.00 | infobox |
| CYP2A6 | Bgee | esophagus | 1.00 | infobox |
| CYP2A6 | Bgee | respiratory epithelium | 1.00 | infobox |
| CYP2A6 | Bgee | thymus | 1.00 | infobox |
| CYP2A6 | Bgee | olfactory epithelium | 1.00 | infobox |
| CYP2A6 | BioGPS | n/a | 1.00 | infobox |
| CYP2A6 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| CYP2A6 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| CYP2A6 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CYP2A6 | End | 40,850,447 bp | 1.00 | infobox |
| CYP2A6 | End | 26,542,973 bp | 1.00 | infobox |
| CYP2A6 | Ensembl | ENSG00000255974 | 1.00 | infobox |
The concept neighborhoods around CYP2A6 bring nearby vocabulary together. In this analysis, examples include Gene, P450 and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CYP2A6, one of the stronger structural bridges in this analysis connects CYP2A6 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CYP2A6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Induction, Distribution & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CYP2A6 · EN edition · Analysis: TopicsToTalkAbout