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Activating transcription factor 2: Function, Interactions & Overview

Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene.

Language: English [EN]
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Activating transcription factor 2 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around Activating transcription factor 2. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
27
Source areas
3
Connected nodes
31
Extracted relationships
126
Concept neighborhoods
14
Bridge connections
31

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 14 topics
Interactions · 12 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHI, 1T2K, 4H36
Band
2q31.1 · 2|2 C3
Bgee
endothelial cell · germinal epithelium · Brodmann area 23 · corpus epididymis · caput epididymis
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Activating transcription factor 2 connects Entity context

The extracted context around Activating transcription factor 2 shows recurring relationship patterns in the source. For example, Activating transcription factor 2 → adipose tissue development, amelogenesis, cAMP response element binding, cAMP response element binding protein binding, cellular response to DNA damage stimulus, chromatin binding, cis-regulatory region sequence-specific DNA binding, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, fat cell differentiation, histone acetylation, histone acetyltransferase activity, membrane, metal ion binding, mitochondrial outer membrane, mitochondrion, mitotic intra-S DNA damage checkpoint signaling Another extracted example is Activating transcription factor 2 → anterior amygdaloid area, arcuate nucleus, Brodmann area 23, caput epididymis, corpus epididymis, dorsomedial hypothalamic nucleus, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, germinal epithelium, habenula, lateral septal nucleus, medial dorsal nucleus, mucosa of paranasal sinus, olfactory tubercle, paraventricular nucleus of hypothalamus, pars compacta, subiculum, tail of epididymis, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.

Activating transcription factor 2

Top relations

Gene ontology · 52
Activating transcription factor 2 → adipose tissue development, amelogenesis, cAMP response element binding, cAMP response element binding protein binding, cellular response to DNA damage stimulus, chromatin binding, cis-regulatory region sequence-specific DNA binding, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, fat cell differentiation, histone acetylation, histone acetyltransferase activity, membrane, metal ion binding, mitochondrial outer membrane, mitochondrion, mitotic intra-S DNA damage checkpoint signaling
Bgee · 20
Activating transcription factor 2 → anterior amygdaloid area, arcuate nucleus, Brodmann area 23, caput epididymis, corpus epididymis, dorsomedial hypothalamic nucleus, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, germinal epithelium, habenula, lateral septal nucleus, medial dorsal nucleus, mucosa of paranasal sinus, olfactory tubercle, paraventricular nucleus of hypothalamus, pars compacta, subiculum, tail of epididymis, ventral tegmental area
RNA expression pattern · 20
Activating transcription factor 2 → anterior amygdaloid area, arcuate nucleus, Brodmann area 23, caput epididymis, corpus epididymis, dorsomedial hypothalamic nucleus, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, germinal epithelium, habenula, lateral septal nucleus, medial dorsal nucleus, mucosa of paranasal sinus, olfactory tubercle, paraventricular nucleus of hypothalamus, pars compacta, subiculum, tail of epididymis, ventral tegmental area
related to Interactions · 11
Activating transcription factor 2 → Activating, C-jun, Casein, CREB, CSNK2A2, JDP2, MAPK14, MAPK8, Mothers, RUVBL2, UBE2I
Band · 2
Activating transcription factor 2 → 2q31.1, 2|2 C3
Chr. · 2
Activating transcription factor 2 → Chromosome 2 (human), Chromosome 2 (mouse)
End · 2
Activating transcription factor 2 → 175,168,382 bp, 73,892,639 bp
Aliases · 1
Activating transcription factor 2 → ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2
Available structures · 1
Activating transcription factor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHI, 1T2K, 4H36
BioGPS · 1
Activating transcription factor 2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human protein transcription gene atf2 factor bp chr band atf-2 chromosome also activating location mouse response function external search 168

Activating transcription factor 2 relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around Activating transcription factor 2. Examples in this analysis include Activating transcription factor 2 → Aliases → ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2 and Activating transcription factor 2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHI, 1T2K, 4H36. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Activating transcription factor 2AliasesATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 21.00infobox
Activating transcription factor 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHI, 1T2K, 4H361.00infobox
Activating transcription factor 2Band2q31.11.00infobox
Activating transcription factor 2Band2|2 C31.00infobox
Activating transcription factor 2Bgeeendothelial cell1.00infobox
Activating transcription factor 2Bgeegerminal epithelium1.00infobox
Activating transcription factor 2BgeeBrodmann area 231.00infobox
Activating transcription factor 2Bgeecorpus epididymis1.00infobox
Activating transcription factor 2Bgeecaput epididymis1.00infobox
Activating transcription factor 2Bgeemucosa of paranasal sinus1.00infobox
Activating transcription factor 2Bgeepars compacta1.00infobox
Activating transcription factor 2Bgeetail of epididymis1.00infobox
Activating transcription factor 2Bgeeganglionic eminence1.00infobox
Activating transcription factor 2BgeeEpithelium of choroid plexus1.00infobox
Activating transcription factor 2Bgeeparaventricular nucleus of hypothalamus1.00infobox
Activating transcription factor 2Bgeemedial dorsal nucleus1.00infobox
Activating transcription factor 2Bgeedorsomedial hypothalamic nucleus1.00infobox
Activating transcription factor 2Bgeehabenula1.00infobox
Activating transcription factor 2Bgeearcuate nucleus1.00infobox
Activating transcription factor 2Bgeeventral tegmental area1.00infobox
Activating transcription factor 2Bgeeolfactory tubercle1.00infobox
Activating transcription factor 2Bgeelateral septal nucleus1.00infobox
Activating transcription factor 2Bgeeanterior amygdaloid area1.00infobox
Activating transcription factor 2Bgeesubiculum1.00infobox
Activating transcription factor 2BioGPSMore reference expression data1.00infobox
Activating transcription factor 2Chr.Chromosome 2 (human)1.00infobox
Activating transcription factor 2Chr.Chromosome 2 (mouse)1.00infobox
Activating transcription factor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Activating transcription factor 2End175,168,382 bp1.00infobox
Activating transcription factor 2End73,892,639 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Activating transcription factor 2 bring nearby vocabulary together. In this analysis, examples include Factor, Activating and Transcription. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Activating transcription factor 2
    • Factor
    • Activating
    • Transcription
    • Atf2
    • Gene
    • Also
    • Location
    • Acetyltransferase
    • Chromatin
    • Histone
    • Sequence-specific
    • External
  • activating transcription factor 2
    • Factor
    • Transcription
    • Activating
    • Atf2
    • Gene
    • Location
    • Human
    • Also
    • Available
    • Binding
    • Function
    • Kinase
  • protein
    • Transcription
    • Atf-2
    • Acetyltransferase
    • Binding
    • C-jun
    • Chromatin
    • Element
    • Epithelial
    • Histone
    • Kinase
    • Sequence-specific
    • Response
  • gene
    • Location
    • Chromosome
    • Human
    • Transcription
    • Bp
    • Chr
    • End
    • Function
    • Search
    • Mouse
    • Band
    • Dna-binding
  • transcription factor
    • Factor
    • Transcription
    • Activating
    • Atf2
    • Gene
    • Location
    • Human
    • Also
    • Available
    • Binding
    • Function
    • Kinase
  • histone acetyltransferase
    • Chromatin
    • Histone
    • Sequence-specific
    • Dna-binding
    • Binding
    • Biological
    • Development
    • Element
    • End
    • Epithelial
    • Function
    • Growth
  • stress-activated protein kinases p38
    • Transcription
    • Atf-2
    • Acetyltransferase
    • Binding
    • C-jun
    • Chromatin
    • Element
    • Epithelial
    • Histone
    • Kinase
    • Sequence-specific
    • Response
  • ras protein
    • Transcription
    • Atf-2
    • Acetyltransferase
    • Binding
    • C-jun
    • Chromatin
    • Element
    • Epithelial
    • Histone
    • Kinase
    • Sequence-specific
    • Response

Connections between topic areas Semantic bridges

For Activating transcription factor 2, one of the stronger structural bridges in this analysis connects Activating transcription factor 2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Activating transcription factor 2Function · splits 17 ⟂ 15
Activating transcription factor 2Interactions · splits 19 ⟂ 13
Activating transcription factor 2Overview · splits 29 ⟂ 3

Map overview Semantic statistics

Activating transcription factor 2

Nodes32
Edges31
Triples126
Avg. degree1.94
Density0.0625
Components1

Source & methodology

TTTA analyzes the structure around Activating transcription factor 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Activating transcription factor 2 · EN edition · Analysis: TopicsToTalkAbout

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