Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Bis(5'-adenosyl)-triphosphatase also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around FHIT.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FHIT shows recurring relationship patterns in the source. For example, FHIT → apex of heart, C1 segment, choroid plexus of fourth ventricle, Epithelium of choroid plexus, gallbladder, human kidney, left adrenal cortex, lumbar spinal ganglion, morula, motor neuron, oocyte, proximal tubule, right adrenal cortex, right adrenal gland, right auricle of heart, right kidney, saccule, seminal vesicula, testicle, transitional epithelium of urinary bladder Another extracted example is FHIT → apoptotic process, bis(5'-adenosyl)-triphosphatase activity, catalytic activity, cytoplasm, cytosol, fibrillar center, hydrolase activity, identical protein binding, intrinsic apoptotic signaling pathway by p53 class mediator, mitochondrion, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nucleotide binding, nucleotide metabolic process, nucleus, plasma membrane, protein binding, purine nucleotide metabolic process, regulation of transcription, DNA-templated, transcription, DNA-templated, ubiquitin protein ligase binding. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp human chr band chromosome 5'-adenosyl bis -triphosphatase fragile histidine triad location function also enzyme mouse protein external pdb
TTTA extracted 95 structured relationships around FHIT. Examples in this analysis include FHIT → 2.7.7.51 → ↗ and FHIT → Aliases → FHIT, AP3Aase, FRA3B, fragile histidine triad, tríada histidina fràgil, fragile histidine triad diadenosine triphosphatase. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FHIT | 2.7.7.51 | ↗ | 1.00 | infobox |
| FHIT | 3.6.1.29 | ↗ | 1.00 | infobox |
| FHIT | 3.6.2.1 | ↗ | 1.00 | infobox |
| FHIT | Aliases | FHIT, AP3Aase, FRA3B, fragile histidine triad, tríada histidina fràgil, fragile histidine triad diadenosine triphosphatase | 1.00 | infobox |
| FHIT | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FHI, 2FHI, 2FIT, 5FIT, 3FIT, 1FIT, 4FIT, 6FIT | 1.00 | infobox |
| FHIT | Band | 3p14.2 | 1.00 | infobox |
| FHIT | Band | 14 A1|14 5.61 cM | 1.00 | infobox |
| FHIT | Bgee | right adrenal gland | 1.00 | infobox |
| FHIT | Bgee | right adrenal cortex | 1.00 | infobox |
| FHIT | Bgee | left adrenal cortex | 1.00 | infobox |
| FHIT | Bgee | apex of heart | 1.00 | infobox |
| FHIT | Bgee | C1 segment | 1.00 | infobox |
| FHIT | Bgee | gallbladder | 1.00 | infobox |
| FHIT | Bgee | oocyte | 1.00 | infobox |
| FHIT | Bgee | right auricle of heart | 1.00 | infobox |
| FHIT | Bgee | testicle | 1.00 | infobox |
| FHIT | Bgee | human kidney | 1.00 | infobox |
| FHIT | Bgee | right kidney | 1.00 | infobox |
| FHIT | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| FHIT | Bgee | transitional epithelium of urinary bladder | 1.00 | infobox |
| FHIT | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| FHIT | Bgee | motor neuron | 1.00 | infobox |
| FHIT | Bgee | saccule | 1.00 | infobox |
| FHIT | Bgee | proximal tubule | 1.00 | infobox |
| FHIT | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| FHIT | Bgee | seminal vesicula | 1.00 | infobox |
| FHIT | Bgee | morula | 1.00 | infobox |
| FHIT | BioGPS | More reference expression data | 1.00 | infobox |
| FHIT | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| FHIT | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
The concept neighborhoods around FHIT bring nearby vocabulary together. In this analysis, examples include Function, Suppressor and Tumor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FHIT, one of the stronger structural bridges in this analysis connects FHIT with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FHIT to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FHIT · EN edition · Analysis: TopicsToTalkAbout