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FHIT

Bis(5'-adenosyl)-triphosphatase also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene.

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7 related topics

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Key facts & relationships

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2.7.7.51
3.6.1.29
3.6.2.1
Aliases
FHIT, AP3Aase, FRA3B, fragile histidine triad, tríada histidina fràgil, fragile histidine triad diadenosine triphosphatase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FHI, 2FHI, 2FIT, 5FIT, 3FIT, 1FIT, 4FIT, 6FIT
Band
3p14.2 · 14 A1|14 5.61 cM

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Map overview Semantic statistics

FHIT

Nodes15
Edges14
Triples95
Avg. degree1.87
Density0.133333
Components1

How this topic connects Entity context

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FHIT

Top relations

Bgee · 20
FHIT → apex of heart, C1 segment, choroid plexus of fourth ventricle, Epithelium of choroid plexus, gallbladder, human kidney, left adrenal cortex, lumbar spinal ganglion, morula, motor neuron, oocyte, proximal tubule, right adrenal cortex, right adrenal gland, right auricle of heart, right kidney, saccule, seminal vesicula, testicle, transitional epithelium of urinary bladder
Gene ontology · 20
FHIT → apoptotic process, bis(5'-adenosyl)-triphosphatase activity, catalytic activity, cytoplasm, cytosol, fibrillar center, hydrolase activity, identical protein binding, intrinsic apoptotic signaling pathway by p53 class mediator, mitochondrion, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nucleotide binding, nucleotide metabolic process, nucleus, plasma membrane, protein binding, purine nucleotide metabolic process, regulation of transcription, DNA-templated, transcription, DNA-templated, ubiquitin protein ligase binding
RNA expression pattern · 20
FHIT → apex of heart, C1 segment, choroid plexus of fourth ventricle, Epithelium of choroid plexus, gallbladder, human kidney, left adrenal cortex, lumbar spinal ganglion, morula, motor neuron, oocyte, proximal tubule, right adrenal cortex, right adrenal gland, right auricle of heart, right kidney, saccule, seminal vesicula, testicle, transitional epithelium of urinary bladder
related to Function · 7
FHIT → FRA3B, In, It, P1, P3-bis, The, This
Band · 2
FHIT → 14 A1|14 5.61 cM, 3p14.2
Chr. · 2
FHIT → Chromosome 14 (mouse), Chromosome 3 (human)
End · 2
FHIT → 12,919,681 bp, 61,251,459 bp
2.7.7.51 · 1
FHIT → ↗
3.6.1.29 · 1
FHIT → ↗
3.6.2.1 · 1
FHIT → ↗

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Important terminology

gene bp human chr band chromosome 5'-adenosyl bis -triphosphatase fragile histidine triad location function also enzyme mouse protein external pdb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FHIT2.7.7.511.00infobox
FHIT3.6.1.291.00infobox
FHIT3.6.2.11.00infobox
FHITAliasesFHIT, AP3Aase, FRA3B, fragile histidine triad, tríada histidina fràgil, fragile histidine triad diadenosine triphosphatase1.00infobox
FHITAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FHI, 2FHI, 2FIT, 5FIT, 3FIT, 1FIT, 4FIT, 6FIT1.00infobox
FHITBand3p14.21.00infobox
FHITBand14 A1|14 5.61 cM1.00infobox
FHITBgeeright adrenal gland1.00infobox
FHITBgeeright adrenal cortex1.00infobox
FHITBgeeleft adrenal cortex1.00infobox
FHITBgeeapex of heart1.00infobox
FHITBgeeC1 segment1.00infobox
FHITBgeegallbladder1.00infobox
FHITBgeeoocyte1.00infobox
FHITBgeeright auricle of heart1.00infobox
FHITBgeetesticle1.00infobox
FHITBgeehuman kidney1.00infobox
FHITBgeeright kidney1.00infobox
FHITBgeelumbar spinal ganglion1.00infobox
FHITBgeetransitional epithelium of urinary bladder1.00infobox
FHITBgeeEpithelium of choroid plexus1.00infobox
FHITBgeemotor neuron1.00infobox
FHITBgeesaccule1.00infobox
FHITBgeeproximal tubule1.00infobox
FHITBgeechoroid plexus of fourth ventricle1.00infobox
FHITBgeeseminal vesicula1.00infobox
FHITBgeemorula1.00infobox
FHITBioGPSMore reference expression data1.00infobox
FHITChr.Chromosome 3 (human)1.00infobox
FHITChr.Chromosome 14 (mouse)1.00infobox

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