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IPO13: Interactions, Nucleocytoplasmic transport & Function

Importin-13 is a protein encoded by the IPO13 gene in humans. Importin-13 is a member of the importin-β family of nuclear transport receptors (NTRs) and was first identified as a transport receptor in 2000. According to PSI-blast based secondary structure PREDiction (PSIPRED), importin-13 contains 38 α-helices. Importin-13 accommodates a range of cargoes…

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IPO13 topic overview

The analysis highlights Interactions, Nucleocytoplasmic transport and Function as prominent areas in the source structure around IPO13.

Related topics
31
Source areas
4
Connected nodes
35
Extracted relationships
70
Concept neighborhoods
10
Bridge connections
35

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 14 topics
Nucleocytoplasmic transport · 9 topics
Function · 4 topics
Overview · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IPO13, IMP13, KAP13, LGL2, RANBP13, importin 13
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2X19, 2XWU, 3ZJY
Band
1p34.1 · 4|4 D1
Bgee
C1 segment · gastrocnemius muscle · apex of heart · muscle of thigh · putamen
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Nucleocytoplasmic transport

Interactions

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IPO13 connects Entity context

The extracted context around IPO13 shows recurring relationship patterns in the source. For example, IPO13 → ankle, apex of heart, C1 segment, corpus callosum, external globus pallidus, extraocular muscle, gastrocnemius muscle, inferior ganglion of vagus nerve, knee joint, medial head of gastrocnemius muscle, muscle of thigh, neural layer of retina, putamen, right frontal lobe, right hemisphere of cerebellum, skeletal muscle tissue, temporal muscle, triceps brachii muscle, vastus lateralis muscle Another extracted example is IPO13 → cytoplasm, intracellular protein transport, nuclear localization sequence binding, nuclear membrane, nucleus, protein binding, protein import into nucleus, protein transport. Use these groups to spot repeated connection types before inspecting the individual relationships.

IPO13

Top relations

Bgee · 19
IPO13 → ankle, apex of heart, C1 segment, corpus callosum, external globus pallidus, extraocular muscle, gastrocnemius muscle, inferior ganglion of vagus nerve, knee joint, medial head of gastrocnemius muscle, muscle of thigh, neural layer of retina, putamen, right frontal lobe, right hemisphere of cerebellum, skeletal muscle tissue, temporal muscle, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 19
IPO13 → ankle, apex of heart, C1 segment, corpus callosum, external globus pallidus, extraocular muscle, gastrocnemius muscle, inferior ganglion of vagus nerve, knee joint, medial head of gastrocnemius muscle, muscle of thigh, neural layer of retina, putamen, right frontal lobe, right hemisphere of cerebellum, skeletal muscle tissue, temporal muscle, triceps brachii muscle, vastus lateralis muscle
Gene ontology · 8
IPO13 → cytoplasm, intracellular protein transport, nuclear localization sequence binding, nuclear membrane, nucleus, protein binding, protein import into nucleus, protein transport
Band · 2
IPO13 → 1p34.1, 4|4 D1
Chr. · 2
IPO13 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
IPO13 → 117,772,196 bp, 43,968,022 bp
Aliases · 1
IPO13 → IPO13, IMP13, KAP13, LGL2, RANBP13, importin 13
Available structures · 1
IPO13 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2X19, 2XWU, 3ZJY
BioGPS · 1
IPO13 → More reference expression data
Databases · 1
IPO13 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

importin-13 nuclear import transport cargoes human bp chr band export binding gene receptors chromosome cargo nucleus location importins receptor release

IPO13 relationships Subject–Predicate–Object triples

TTTA extracted 70 structured relationships around IPO13. Examples in this analysis include IPO13 → Aliases → IPO13, IMP13, KAP13, LGL2, RANBP13, importin 13 and IPO13 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2X19, 2XWU, 3ZJY. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IPO13AliasesIPO13, IMP13, KAP13, LGL2, RANBP13, importin 131.00infobox
IPO13Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2X19, 2XWU, 3ZJY1.00infobox
IPO13Band1p34.11.00infobox
IPO13Band4|4 D11.00infobox
IPO13BgeeC1 segment1.00infobox
IPO13Bgeegastrocnemius muscle1.00infobox
IPO13Bgeeapex of heart1.00infobox
IPO13Bgeemuscle of thigh1.00infobox
IPO13Bgeeputamen1.00infobox
IPO13Bgeecorpus callosum1.00infobox
IPO13Bgeeright hemisphere of cerebellum1.00infobox
IPO13Bgeeinferior ganglion of vagus nerve1.00infobox
IPO13Bgeeright frontal lobe1.00infobox
IPO13Bgeeexternal globus pallidus1.00infobox
IPO13Bgeeneural layer of retina1.00infobox
IPO13Bgeeskeletal muscle tissue1.00infobox
IPO13Bgeeknee joint1.00infobox
IPO13Bgeemedial head of gastrocnemius muscle1.00infobox
IPO13Bgeevastus lateralis muscle1.00infobox
IPO13Bgeeextraocular muscle1.00infobox
IPO13Bgeetemporal muscle1.00infobox
IPO13Bgeetriceps brachii muscle1.00infobox
IPO13Bgeeankle1.00infobox
IPO13BioGPSMore reference expression data1.00infobox
IPO13Chr.Chromosome 1 (human)1.00infobox
IPO13Chr.Chromosome 4 (mouse)1.00infobox
IPO13DatabasesNCBI: entry; OMA: entry1.00infobox
IPO13End43,968,022 bp1.00infobox
IPO13End117,772,196 bp1.00infobox
IPO13EnsemblENSG000001174081.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IPO13 bring nearby vocabulary together. In this analysis, examples include Expressed, External and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • nuclear pore complexes
    • Import
    • Transport
    • Export
    • Receptors
    • Ntrs
    • Bind
    • Factors
    • Receptor
    • Cargoes
    • Cargo
    • Importins
    • Nucleus
  • nuclear envelope
    • Import
    • Transport
    • Export
    • Receptors
    • Ntrs
    • Bind
    • Factors
    • Receptor
    • Cargoes
    • Cargo
    • Importins
    • Nucleus
  • nucleocytoplasmic transport
    • Receptors
    • Nuclear
    • Import
    • Due
    • Export
    • External
    • Function
    • Ntrs
    • Location
    • Receptor
    • Cargo
    • Chromosome
  • IPO13
    • Expressed
    • External
    • Function
    • Heart
    • Human
    • Protein
    • Location
    • Chromosome
    • Bp
    • Chr
    • Brain
    • Lung
  • ipo13
    • Expressed
    • External
    • Function
    • Heart
    • Human
    • Protein
    • Location
    • Chromosome
    • Bp
    • Chr
    • Brain
    • Lung
  • function
    • External
    • Location
    • Chromosome
    • Gene
    • Ipo13
    • Bp
    • Chr
    • Human
    • Heart
    • Mouse
    • Protein
    • Cytoplasm
  • transcription factors
    • Ntrs
    • Known
    • Rangtp
    • Receptor
    • Importins
    • Nuclear
    • Export
    • Importin-13
    • Transport
    • Import
  • glucocorticoid receptor
    • Transport
    • Factors
    • Known
    • Cargoes
    • Import
    • Importins
    • Receptors
    • Export

Connections between topic areas Semantic bridges

For IPO13, one of the stronger structural bridges in this analysis connects IPO13 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IPO13 — Interactions · splits 21 ⟂ 15
IPO13 — Nucleocytoplasmic transport · splits 26 ⟂ 10
IPO13 — Overview · splits 31 ⟂ 5
IPO13 — Function · splits 31 ⟂ 5

Map overview Semantic statistics

IPO13

Nodes36
Edges35
Triples70
Avg. degree1.94
Density0.055556
Components1

Source & methodology

TTTA analyzes the structure around IPO13 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Nucleocytoplasmic transport & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IPO13 · EN edition · Analysis: TopicsToTalkAbout

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