DACH1

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Structure

Amino acid Dachshund Family Exons Chromosome 13 Chromatin

20 related topics

Disease relevance

Cyclin D1 Estrogen Progesterone ERa+Podocyte

6 related topics

Function

D. melanogaster Cell proliferation Retinal Pituitary Inhibits migration

5 related topics

Overview

Protein Gene Interact Ubc9

4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: DACH1, DACH, dachshund family transcription factor 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1L8R
Band: 13q21.33 · 14 E2.1|14 48.25 cM
Bgee: ventricular zone · endothelial cell · ganglionic eminence · buccal mucosa cell · glomerulus
BioGPS: More reference expression data
Chr.: Chromosome 13 (human) · Chromosome 14 (mouse)

Topics to explore

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Overview

Protein
Gene
Interact Protein-protein interaction
Ubc9 UBE2I

Structure

Amino acid
Dachshund Family Dachshund (gene)
Exons Exon
Chromosome 13
Chromatin
DNA-binding DNA-binding domain
Transcription factors Transcription factor
Cell Cell (biology)
Isoforms Protein isoform
Alternatively spliced Alternative splicing
MRNA Messenger RNA
Kidney
Heart
Helix–turn–helix family Helix-turn-helix
X-ray crystal structure X-ray crystallography
Oncogenes Oncogene
DNA binding proteins DNA-binding protein
Bone marrow
Leucocyte White blood cell
Pineal gland

Function

Disease relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes40

Edges39

Triples136

Avg. degree1.95

Density0.05

Components1

How this topic connects Entity context

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DACH1

Top relations

Gene ontology · 28

DACH1 → cell population proliferation, cytoplasm, development of primary female sexual characteristics, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, multicellular organism development, negative regulation of cell migration, negative regulation of cell proliferation involved in contact inhibition, negative regulation of DNA biosynthetic process, negative regulation of fibroblast proliferation, negative regulation of transcription by competitive promoter binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleus, protein binding, regulation of nuclear cell cycle DNA replication, regulation of transcription, DNA-templated, respiratory gaseous exchange by respiratory system

Bgee · 18

DACH1 → buccal mucosa cell, dorsal striatum, endothelial cell, ganglionic eminence, glomerulus, gonad, granulocyte, hair follicle, left lung lobe, lobe of prostate, medullary collecting duct, metanephric glomerulus, metanephros, renal corpuscle, vas deferens, ventricular zone, vestibular membrane of cochlear duct, visceral pleura

RNA expression pattern · 18

related to Gene structure · 13

DACH1 → Box-N, DACH, DACH1 Box-N, Dachshund, Dachshund Family, DD1, DNA, DNA-binding, Four, It, Multiple, The X-ray, This

related to Nephropathy · 8

DACH1 → BMP4, Double, Functional, It, R684C, Renal, RHD, TGF-β

related to Protein modification · 7

DACH1 → Acetylation, DACH, EMT, HDAC, Phosphorylation, SUMOYlation, YB-1

related to Transcription · 7

DACH1 → CA150, Curiously, EMT, FKHR, Forkhead-like DNA, Jun, Snail1

related to Cancer · 6

DACH1 → Approximately, Cyclin D1, ERa, Normal, Supporting, These

related to Diabetes · 5

DACH1 → DACH1 Is Increased, HDAC4, Hepatocyte, Nuclear Exclusion, Obese

Band · 2

DACH1 → 13q21.33, 14 E2.1|14 48.25 cM

Important terminology Word statistics

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Important terminology

gene protein cell human bp transcription binding chr band chromosome 13 cancer expression including breast factor prostate dachshund mrna kidney

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
DACH1	Aliases	DACH1, DACH, dachshund family transcription factor 1	1.00	infobox
DACH1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1L8R	1.00	infobox
DACH1	Band	13q21.33	1.00	infobox
DACH1	Band	14 E2.1\|14 48.25 cM	1.00	infobox
DACH1	Bgee	ventricular zone	1.00	infobox
DACH1	Bgee	endothelial cell	1.00	infobox
DACH1	Bgee	ganglionic eminence	1.00	infobox
DACH1	Bgee	buccal mucosa cell	1.00	infobox
DACH1	Bgee	glomerulus	1.00	infobox
DACH1	Bgee	hair follicle	1.00	infobox
DACH1	Bgee	metanephros	1.00	infobox
DACH1	Bgee	gonad	1.00	infobox
DACH1	Bgee	visceral pleura	1.00	infobox
DACH1	Bgee	metanephric glomerulus	1.00	infobox
DACH1	Bgee	renal corpuscle	1.00	infobox
DACH1	Bgee	left lung lobe	1.00	infobox
DACH1	Bgee	medullary collecting duct	1.00	infobox
DACH1	Bgee	vas deferens	1.00	infobox
DACH1	Bgee	granulocyte	1.00	infobox
DACH1	Bgee	dorsal striatum	1.00	infobox
DACH1	Bgee	lobe of prostate	1.00	infobox
DACH1	Bgee	vestibular membrane of cochlear duct	1.00	infobox
DACH1	BioGPS	More reference expression data	1.00	infobox
DACH1	Chr.	Chromosome 13 (human)	1.00	infobox
DACH1	Chr.	Chromosome 14 (mouse)	1.00	infobox
DACH1	Databases	NCBI: entry; OMA: entry	1.00	infobox
DACH1	End	71,867,204 bp	1.00	infobox
DACH1	End	98,407,201 bp	1.00	infobox
DACH1	Ensembl	ENSG00000276644	1.00	infobox
DACH1	Entrez	1602	1.00	infobox

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