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SENP1

Sentrin-specific protease 1 is an enzyme that in humans is encoded by the SENP1 gene.

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Explore the main themes, entities and connections around SENP1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Features

7 related topics

General

4 related topics

Location

2 related topics

Function

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SENP1, SuPr-2, SUMO1/sentrin specific peptidase 1, SUMO specific peptidase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CKG, 2CKH, 2G4D, 2IY0, 2IY1, 2IYC, 2IYD, 2XPH, 2XRE
Band
12q13.11 · 15 F1|15 54.04 cM
Bgee
testicle · right testis · left testis · sperm · buccal mucosa cell
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 15 (mouse)

Topics to explore

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Overview

General

Features

Location

Function

Advanced semantic analysis

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Map overview Semantic statistics

SENP1

Nodes23
Edges22
Triples108
Avg. degree1.91
Density0.086957
Components1

How this topic connects Entity context

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SENP1

Top relations

Gene ontology · 20
SENP1 → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cysteine-type peptidase activity, cytoplasm, endopeptidase activity, focal adhesion, hydrolase activity, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nuclear membrane, nucleoplasm, nucleus, peptidase activity, positive regulation of transcription by RNA polymerase II, protein binding, protein desumoylation, protein sumoylation, proteolysis, regulation of definitive erythrocyte differentiation, SUMO-specific endopeptidase activity, SUMO-specific protease activity
Bgee · 19
SENP1 → Achilles tendon, aortic valve, ascending aorta, bone marrow cell, buccal mucosa cell, epiblast, ganglionic eminence, genital tubercle, left testis, right testis, Rostral migratory stream, secondary oocyte, sperm, spermatid, spermatocyte, tail of embryo, testicle, ventricular zone, zygote
RNA expression pattern · 19
SENP1 → Achilles tendon, aortic valve, ascending aorta, bone marrow cell, buccal mucosa cell, epiblast, ganglionic eminence, genital tubercle, left testis, right testis, Rostral migratory stream, secondary oocyte, sperm, spermatid, spermatocyte, tail of embryo, testicle, ventricular zone, zygote
related to General · 9
SENP1 → C-terminal, N-terminal, SENP1-3, SENP5-7, SUMO, SUMO-specific, The, The C-terminal, There
related to Function · 7
SENP1 → Ala-Thr-Tyr, C-terminus, Gly-Gly, In, SUMO, SUMO-1, This
related to Features · 6
SENP1 → B70, EC, It, N-terminal, Sentrin-specific, The
related to Location · 4
SENP1 → Both SENP1, C-terminus, NES, The
Band · 2
SENP1 → 12q13.11, 15 F1|15 54.04 cM
Chr. · 2
SENP1 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
SENP1 → 48,106,079 bp, 97,991,625 bp

Important terminology Word statistics

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Important terminology

bp human chr band gene sumo protease location chromosome 12 protein nucleus sentrin-specific humans end proteases n-terminal mouse cell function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SENP1AliasesSENP1, SuPr-2, SUMO1/sentrin specific peptidase 1, SUMO specific peptidase 11.00infobox
SENP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CKG, 2CKH, 2G4D, 2IY0, 2IY1, 2IYC, 2IYD, 2XPH, 2XRE1.00infobox
SENP1Band12q13.111.00infobox
SENP1Band15 F1|15 54.04 cM1.00infobox
SENP1Bgeetesticle1.00infobox
SENP1Bgeeright testis1.00infobox
SENP1Bgeeleft testis1.00infobox
SENP1Bgeesperm1.00infobox
SENP1Bgeebuccal mucosa cell1.00infobox
SENP1BgeeAchilles tendon1.00infobox
SENP1Bgeeventricular zone1.00infobox
SENP1Bgeebone marrow cell1.00infobox
SENP1Bgeeganglionic eminence1.00infobox
SENP1Bgeezygote1.00infobox
SENP1Bgeesecondary oocyte1.00infobox
SENP1Bgeespermatocyte1.00infobox
SENP1Bgeespermatid1.00infobox
SENP1Bgeetail of embryo1.00infobox
SENP1Bgeeascending aorta1.00infobox
SENP1Bgeegenital tubercle1.00infobox
SENP1Bgeeaortic valve1.00infobox
SENP1BgeeRostral migratory stream1.00infobox
SENP1Bgeeepiblast1.00infobox
SENP1BioGPSn/a1.00infobox
SENP1Chr.Chromosome 12 (human)1.00infobox
SENP1Chr.Chromosome 15 (mouse)1.00infobox
SENP1DatabasesNCBI: entry; OMA: entry1.00infobox
SENP1End48,106,079 bp1.00infobox
SENP1End97,991,625 bp1.00infobox
SENP1EnsemblENSG000000793871.00infobox

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