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SENP1: Geography, Features & General

Sentrin-specific protease 1 is an enzyme that in humans is encoded by the SENP1 gene.

Language: English [EN]
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SENP1 topic overview

The analysis highlights Geography, Features and General as prominent areas in the source structure around SENP1.

Related topics
17
Source areas
5
Connected nodes
22
Extracted relationships
108
Concept neighborhoods
10
Bridge connections
22

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Features · 7 topics
General · 4 topics
Function · 2 topics
Location · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SENP1, SuPr-2, SUMO1/sentrin specific peptidase 1, SUMO specific peptidase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CKG, 2CKH, 2G4D, 2IY0, 2IY1, 2IYC, 2IYD, 2XPH, 2XRE
Band
12q13.11 · 15 F1|15 54.04 cM
Bgee
testicle · right testis · left testis · sperm · buccal mucosa cell
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

General

Features

Location

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SENP1 connects Entity context

The extracted context around SENP1 shows recurring relationship patterns in the source. For example, SENP1 → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cysteine-type peptidase activity, cytoplasm, endopeptidase activity, focal adhesion, hydrolase activity, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nuclear membrane, nucleoplasm, nucleus, peptidase activity, positive regulation of transcription by RNA polymerase II, protein binding, protein desumoylation, protein sumoylation, proteolysis, regulation of definitive erythrocyte differentiation, SUMO-specific endopeptidase activity, SUMO-specific protease activity Another extracted example is SENP1 → Achilles tendon, aortic valve, ascending aorta, bone marrow cell, buccal mucosa cell, epiblast, ganglionic eminence, genital tubercle, left testis, right testis, Rostral migratory stream, secondary oocyte, sperm, spermatid, spermatocyte, tail of embryo, testicle, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

SENP1

Top relations

Gene ontology · 20
SENP1 → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cysteine-type peptidase activity, cytoplasm, endopeptidase activity, focal adhesion, hydrolase activity, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nuclear membrane, nucleoplasm, nucleus, peptidase activity, positive regulation of transcription by RNA polymerase II, protein binding, protein desumoylation, protein sumoylation, proteolysis, regulation of definitive erythrocyte differentiation, SUMO-specific endopeptidase activity, SUMO-specific protease activity
Bgee · 19
SENP1 → Achilles tendon, aortic valve, ascending aorta, bone marrow cell, buccal mucosa cell, epiblast, ganglionic eminence, genital tubercle, left testis, right testis, Rostral migratory stream, secondary oocyte, sperm, spermatid, spermatocyte, tail of embryo, testicle, ventricular zone, zygote
RNA expression pattern · 19
SENP1 → Achilles tendon, aortic valve, ascending aorta, bone marrow cell, buccal mucosa cell, epiblast, ganglionic eminence, genital tubercle, left testis, right testis, Rostral migratory stream, secondary oocyte, sperm, spermatid, spermatocyte, tail of embryo, testicle, ventricular zone, zygote
related to General · 9
SENP1 → C-terminal, N-terminal, SENP1-3, SENP5-7, SUMO, SUMO-specific, The, The C-terminal, There
related to Function · 7
SENP1 → Ala-Thr-Tyr, C-terminus, Gly-Gly, In, SUMO, SUMO-1, This
related to Features · 6
SENP1 → B70, EC, It, N-terminal, Sentrin-specific, The
related to Location · 4
SENP1 → Both SENP1, C-terminus, NES, The
Band · 2
SENP1 → 12q13.11, 15 F1|15 54.04 cM
Chr. · 2
SENP1 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
SENP1 → 48,106,079 bp, 97,991,625 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human chr band gene sumo protease location chromosome 12 protein nucleus sentrin-specific humans end proteases n-terminal mouse cell function

SENP1 relationships Subject–Predicate–Object triples

TTTA extracted 108 structured relationships around SENP1. Examples in this analysis include SENP1 → Aliases → SENP1, SuPr-2, SUMO1/sentrin specific peptidase 1, SUMO specific peptidase 1 and SENP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CKG, 2CKH, 2G4D, 2IY0, 2IY1, 2IYC, 2IYD, 2XPH, 2XRE. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SENP1AliasesSENP1, SuPr-2, SUMO1/sentrin specific peptidase 1, SUMO specific peptidase 11.00infobox
SENP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CKG, 2CKH, 2G4D, 2IY0, 2IY1, 2IYC, 2IYD, 2XPH, 2XRE1.00infobox
SENP1Band12q13.111.00infobox
SENP1Band15 F1|15 54.04 cM1.00infobox
SENP1Bgeetesticle1.00infobox
SENP1Bgeeright testis1.00infobox
SENP1Bgeeleft testis1.00infobox
SENP1Bgeesperm1.00infobox
SENP1Bgeebuccal mucosa cell1.00infobox
SENP1BgeeAchilles tendon1.00infobox
SENP1Bgeeventricular zone1.00infobox
SENP1Bgeebone marrow cell1.00infobox
SENP1Bgeeganglionic eminence1.00infobox
SENP1Bgeezygote1.00infobox
SENP1Bgeesecondary oocyte1.00infobox
SENP1Bgeespermatocyte1.00infobox
SENP1Bgeespermatid1.00infobox
SENP1Bgeetail of embryo1.00infobox
SENP1Bgeeascending aorta1.00infobox
SENP1Bgeegenital tubercle1.00infobox
SENP1Bgeeaortic valve1.00infobox
SENP1BgeeRostral migratory stream1.00infobox
SENP1Bgeeepiblast1.00infobox
SENP1BioGPSn/a1.00infobox
SENP1Chr.Chromosome 12 (human)1.00infobox
SENP1Chr.Chromosome 15 (mouse)1.00infobox
SENP1DatabasesNCBI: entry; OMA: entry1.00infobox
SENP1End48,106,079 bp1.00infobox
SENP1End97,991,625 bp1.00infobox
SENP1EnsemblENSG000000793871.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SENP1 bring nearby vocabulary together. In this analysis, examples include Sumo, Nucleus and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SENP1
    • Sumo
    • Nucleus
    • Gene
    • Human
    • Function
    • Peptidase
    • Search
    • Cell
    • Location
    • Sentrin-specific
    • Chromosome
    • Protein
  • senp1
    • Sumo
    • Nucleus
    • Gene
    • Human
    • Function
    • Peptidase
    • Search
    • Cell
    • Location
    • Sentrin-specific
    • Chromosome
    • Protein
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • F1
    • Function
    • Human
    • Mouse
    • Peptidase
    • Search
    • End
    • Humans
  • function
    • Peptidase
    • Search
    • Location
    • Chromosome
    • External
    • Gene
    • Bp
    • Chr
    • Human
    • F1
    • Mouse
    • Pdb
  • location
    • Chromosome
    • F1
    • Mouse
    • Peptidase
    • Search
    • Bp
    • Chr
    • Human
    • End
    • Band
    • Sumo
    • Pdb
  • proteases
    • Q9p0u3
    • Search
    • Uniprot
    • Acids
    • Amino
    • N-terminal
    • Three
    • Protein
    • Sumo
    • Senp1
  • cysteine proteases
    • Q9p0u3
    • Search
    • Uniprot
    • Acids
    • Amino
    • N-terminal
    • Three
    • Protein
    • Sumo
    • Senp1
  • nucleus
    • Senp1
    • Peptidase
    • Q9p0u3
    • Search
    • Uniprot
    • Located
    • Proteases
    • Protease
    • Protein
    • Sumo

Connections between topic areas Semantic bridges

For SENP1, one of the stronger structural bridges in this analysis connects SENP1 with Features. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SENP1Features · splits 15 ⟂ 8
SENP1General · splits 18 ⟂ 5
SENP1Overview · splits 20 ⟂ 3
SENP1Location · splits 20 ⟂ 3
SENP1Function · splits 20 ⟂ 3

Map overview Semantic statistics

SENP1

Nodes23
Edges22
Triples108
Avg. degree1.91
Density0.086957
Components1

Source & methodology

TTTA analyzes the structure around SENP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography, Features & General, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SENP1 · EN edition · Analysis: TopicsToTalkAbout

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