RANGAP1

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Function

Homodimeric GTPase RAN GTP/GDP cycle RAS RCC1

8 related topics

Interactions

Interact Ran UBE2I

3 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: RANGAP1, Fug1, RANGAP, SD, Ran GTPase activating protein 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2IY0, 3UIN, 3UIO, 3UIP, 5D2M, 2IO2, 2IO3
Band: 22q13.2 · 15 E1|15 38.21 cM
Bgee: left testis · right testis · Brodmann area 10 · right frontal lobe · cingulate gyrus
BioGPS: More reference expression data
Chr.: Chromosome 22 (human) · Chromosome 15 (mouse)

Topics to explore

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Overview

Function

Homodimeric
GTPase
RAN GTP/GDP cycle Ran (protein)
RAS Ras GTPase
RCC1
GTP Guanosine triphosphate
GTPase activators GTPase activator
RAS-related proteins Ras superfamily

Interactions

Interact Protein-protein interaction
Ran Ran (gene)
UBE2I

Advanced semantic analysis

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Map overview Semantic statistics

Nodes17

Edges16

Triples111

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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RANGAP1

Top relations

Gene ontology · 33

RANGAP1 → activation of GTPase activity, aggresome, axon cytoplasm, cadherin binding, cellular response to peptide hormone stimulus, cellular response to vasopressin, chromosome, chromosome, centromeric region, cytoplasm, cytoplasmic periphery of the nuclear pore complex, cytoskeleton, cytosol, dendrite, GTPase activator activity, intracellular membrane-bounded organelle, kinetochore, mitotic spindle, negative regulation of protein export from nucleus, nuclear envelope, nuclear membrane

Bgee · 20

RANGAP1 → anterior cingulate cortex, Brodmann area 10, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, epiblast, gallbladder, left testis, middle frontal gyrus, primary visual cortex, right frontal lobe, right testis, seminiferous tubule, skin of abdomen, skin of leg, spermatid, superior frontal gyrus, superior surface of tongue, visual cortex, yolk sac

RNA expression pattern · 20

related to Function · 12

RANGAP1 → Fug1, GTP-bound, GTPase, RAN, RAN GTP/GDP, RAN-dependent, RAS, RAS-related, RCC1, Rna1p, The, The RANGAP1

Band · 2

RANGAP1 → 15 E1|15 38.21 cM, 22q13.2

Chr. · 2

RANGAP1 → Chromosome 15 (mouse), Chromosome 22 (human)

End · 2

RANGAP1 → 41,286,187 bp, 81,629,731 bp

is a · 2

RANGAP1 → immediate antagonist of RCC1, key regulator of the RAN GTP/GDP cycle

Aliases · 1

RANGAP1 → RANGAP1, Fug1, RANGAP, SD, Ran GTPase activating protein 1

Available structures · 1

RANGAP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2IY0, 3UIN, 3UIO, 3UIP, 5D2M, 2IO2, 2IO3

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ran bp gene chr human chromosome band protein 22 gtpase location nucleus cytoplasm mouse function search 286 187 end 41

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
RANGAP1	Aliases	RANGAP1, Fug1, RANGAP, SD, Ran GTPase activating protein 1	1.00	infobox
RANGAP1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2IY0, 3UIN, 3UIO, 3UIP, 5D2M, 2IO2, 2IO3	1.00	infobox
RANGAP1	Band	22q13.2	1.00	infobox
RANGAP1	Band	15 E1\|15 38.21 cM	1.00	infobox
RANGAP1	Bgee	left testis	1.00	infobox
RANGAP1	Bgee	right testis	1.00	infobox
RANGAP1	Bgee	Brodmann area 10	1.00	infobox
RANGAP1	Bgee	right frontal lobe	1.00	infobox
RANGAP1	Bgee	cingulate gyrus	1.00	infobox
RANGAP1	Bgee	anterior cingulate cortex	1.00	infobox
RANGAP1	Bgee	skin of abdomen	1.00	infobox
RANGAP1	Bgee	Brodmann area 9	1.00	infobox
RANGAP1	Bgee	skin of leg	1.00	infobox
RANGAP1	Bgee	middle frontal gyrus	1.00	infobox
RANGAP1	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
RANGAP1	Bgee	superior surface of tongue	1.00	infobox
RANGAP1	Bgee	spermatid	1.00	infobox
RANGAP1	Bgee	yolk sac	1.00	infobox
RANGAP1	Bgee	visual cortex	1.00	infobox
RANGAP1	Bgee	superior frontal gyrus	1.00	infobox
RANGAP1	Bgee	seminiferous tubule	1.00	infobox
RANGAP1	Bgee	gallbladder	1.00	infobox
RANGAP1	Bgee	primary visual cortex	1.00	infobox
RANGAP1	Bgee	epiblast	1.00	infobox
RANGAP1	BioGPS	More reference expression data	1.00	infobox
RANGAP1	Chr.	Chromosome 22 (human)	1.00	infobox
RANGAP1	Chr.	Chromosome 15 (mouse)	1.00	infobox
RANGAP1	Databases	NCBI: entry; OMA: entry	1.00	infobox
RANGAP1	End	41,286,187 bp	1.00	infobox
RANGAP1	End	81,629,731 bp	1.00	infobox

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