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CRADD: Interactions & Overview

Death domain-containing protein CRADD is a protein that in humans is encoded by the CRADD gene.

Language: English [EN]
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CRADD topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around CRADD.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
85
Concept neighborhoods
7
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CRADD, MRT34, RAIDD, CASP2 and RIPK1 domain containing adaptor with death domain
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O71, 2OF5, 3CRD
Band
12q22 · 10 C2|10 49.26 cM
Bgee
testicle · left ventricle · right lobe of liver · apex of heart · gonad
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CRADD connects Entity context

The extracted context around CRADD shows recurring relationship patterns in the source. For example, CRADD → apex of heart, cardiac muscle tissue of left ventricle, embryo, genital tubercle, gonad, granulocyte, Ileal epithelium, islet of Langerhans, left adrenal gland, left testis, left ventricle, medial ganglionic eminence, muscle of thigh, proximal tubule, right auricle of heart, right kidney, right lobe of liver, right testis, tail of embryo, testicle Another extracted example is CRADD → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular response to mechanical stimulus, cytoplasm, cytosol, death domain binding, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, extrinsic apoptotic signaling pathway via death domain receptors, nucleus, positive regulation of apoptotic process, positive regulation of apoptotic signaling pathway, protease binding, protein binding, protein-macromolecule adaptor activity, regulation of apoptotic process, signal transduction. Use these groups to spot repeated connection types before inspecting the individual relationships.

CRADD

Top relations

Bgee · 20
CRADD → apex of heart, cardiac muscle tissue of left ventricle, embryo, genital tubercle, gonad, granulocyte, Ileal epithelium, islet of Langerhans, left adrenal gland, left testis, left ventricle, medial ganglionic eminence, muscle of thigh, proximal tubule, right auricle of heart, right kidney, right lobe of liver, right testis, tail of embryo, testicle
RNA expression pattern · 20
CRADD → apex of heart, cardiac muscle tissue of left ventricle, embryo, genital tubercle, gonad, granulocyte, Ileal epithelium, islet of Langerhans, left adrenal gland, left testis, left ventricle, medial ganglionic eminence, muscle of thigh, proximal tubule, right auricle of heart, right kidney, right lobe of liver, right testis, tail of embryo, testicle
Gene ontology · 17
CRADD → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular response to mechanical stimulus, cytoplasm, cytosol, death domain binding, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, extrinsic apoptotic signaling pathway via death domain receptors, nucleus, positive regulation of apoptotic process, positive regulation of apoptotic signaling pathway, protease binding, protein binding, protein-macromolecule adaptor activity, regulation of apoptotic process, signal transduction
Band · 2
CRADD → 10 C2|10 49.26 cM, 12q22
Chr. · 2
CRADD → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
CRADD → 93,894,840 bp, 95,159,995 bp
related to External links · 2
CRADD → Human CRADD, UCSC Genome Browser
related to Interactions · 2
CRADD → Caspase, RIPK1
Aliases · 1
CRADD → CRADD, MRT34, RAIDD, CASP2 and RIPK1 domain containing adaptor with death domain
Available structures · 1
CRADD → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O71, 2OF5, 3CRD

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human chr band death chromosome 12 protein location domain ripk1 mouse cell function external domain-containing encoded adaptor search

CRADD relationships Subject–Predicate–Object triples

TTTA extracted 85 structured relationships around CRADD. Examples in this analysis include CRADD → Aliases → CRADD, MRT34, RAIDD, CASP2 and RIPK1 domain containing adaptor with death domain and CRADD → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O71, 2OF5, 3CRD. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CRADDAliasesCRADD, MRT34, RAIDD, CASP2 and RIPK1 domain containing adaptor with death domain1.00infobox
CRADDAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O71, 2OF5, 3CRD1.00infobox
CRADDBand12q221.00infobox
CRADDBand10 C2|10 49.26 cM1.00infobox
CRADDBgeetesticle1.00infobox
CRADDBgeeleft ventricle1.00infobox
CRADDBgeeright lobe of liver1.00infobox
CRADDBgeeapex of heart1.00infobox
CRADDBgeegonad1.00infobox
CRADDBgeeislet of Langerhans1.00infobox
CRADDBgeeright auricle of heart1.00infobox
CRADDBgeeright testis1.00infobox
CRADDBgeeleft testis1.00infobox
CRADDBgeeleft adrenal gland1.00infobox
CRADDBgeegranulocyte1.00infobox
CRADDBgeegenital tubercle1.00infobox
CRADDBgeemuscle of thigh1.00infobox
CRADDBgeeright kidney1.00infobox
CRADDBgeeproximal tubule1.00infobox
CRADDBgeetail of embryo1.00infobox
CRADDBgeeIleal epithelium1.00infobox
CRADDBgeecardiac muscle tissue of left ventricle1.00infobox
CRADDBgeemedial ganglionic eminence1.00infobox
CRADDBgeeembryo1.00infobox
CRADDBioGPSn/a1.00infobox
CRADDChr.Chromosome 12 (human)1.00infobox
CRADDChr.Chromosome 10 (mouse)1.00infobox
CRADDDatabasesNCBI: entry; OMA: entry1.00infobox
CRADDEnd93,894,840 bp1.00infobox
CRADDEnd95,159,995 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CRADD bring nearby vocabulary together. In this analysis, examples include Gene, Death and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CRADD
    • Gene
    • Death
    • Location
    • Human
    • Adaptor
    • Encoded
    • Function
    • Search
    • Shown
    • Ucsc
    • Domain
    • Protein
  • cradd
    • Gene
    • Death
    • Location
    • Human
    • Adaptor
    • Encoded
    • Function
    • Search
    • Shown
    • Ucsc
    • Domain
    • Protein
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Adaptor
    • C2
    • End
    • Function
    • Mouse
    • Search
    • Ucsc
  • caspase 2
    • Ripk1
    • Cell
    • Domain-containing
    • Shown
    • Signal
    • Transduction
    • Domain
    • Protein
    • Death
    • Cradd
  • ripk1
    • Caspase
    • Card
    • Cell
    • Search
    • Shown
    • Signal
    • Transduction
    • Protein
  • protein
    • Signal
    • Transduction
    • Caspase
    • Search
    • Shown
    • Ucsc
    • Ripk1
  • interactions
    • References
    • Search
    • Ripk1
    • Location
    • Human

Connections between topic areas Semantic bridges

For CRADD, one of the stronger structural bridges in this analysis connects CRADD with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CRADDInteractions · splits 4 ⟂ 4
CRADDOverview · splits 5 ⟂ 3

Map overview Semantic statistics

CRADD

Nodes8
Edges7
Triples85
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around CRADD to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CRADD · EN edition · Analysis: TopicsToTalkAbout

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